Search Results - "Huang, Rongqin"

Multifunctional Mesoporous Silica-Coated Graphene Nanosheet Used for Chemo-Photothermal Synergistic Targeted Therapy of Glioma by Wang, Yi, Wang, Kaiyuan, Zhao, Jianfeng, Liu, Xingang, Bu, Juan, Yan, Xueying, Huang, Rongqin

“…Current therapy of malignant glioma in clinic is unsatisfactory with poor patient compliance due to low therapeutic efficiency and strong systemic side…”
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Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma by Huang, Shixian, Li, Jianfeng, Han, Liang, Liu, Shuhuan, Ma, Haojun, Huang, Rongqin, Jiang, Chen

“…Abstract Gene therapy offers a promising cure of brain glioma and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is able to induce cell…”
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Plasmid pORF-hTRAIL and doxorubicin co-delivery targeting to tumor using peptide-conjugated polyamidoamine dendrimer by Han, Liang, Huang, Rongqin, Li, Jianfeng, Liu, Shuhuan, Huang, Shixian, Jiang, Chen

“…Abstract A combination cancer therapy was investigated via co-delivery of therapeutic gene encoding human tumor necrosis factor-related apoptosis-inducing…”
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Angiopep-2 modified PE-PEG based polymeric micelles for amphotericin B delivery targeted to the brain by Shao, Kun, Huang, Rongqin, Li, Jianfeng, Han, Liang, Ye, Liya, Lou, Jinning, Jiang, Chen

“…Amphotericin B (AmB) is a poorly water soluble antibiotic and is used to treat fungal infections of the central nervous system (CNS). However, AmB shows poor…”
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MRI-Visualized, Dual-Targeting, Combined Tumor Therapy Using Magnetic Graphene-Based Mesoporous Silica by Wang, Yi, Huang, Rongqin, Liang, Guohai, Zhang, Zhengyong, Zhang, Peng, Yu, Shaoning, Kong, Jilie

“…Targeting peptide‐modified magnetic graphene‐based mesoporous silica (MGMSPI) are synthesized, characterized, and developed as a multifunctional theranostic…”
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Enhanced blood–brain barrier penetration and glioma therapy mediated by a new peptide modified gene delivery system by Yao, Hui, Wang, Kaiyuan, Wang, Yi, Wang, Shanshan, Li, Jianfeng, Lou, Jinning, Ye, Liya, Yan, Xueying, Lu, Weiyue, Huang, Rongqin

“…Abstract Successful glioma gene therapy lays on two important factors, the therapeutic genes and efficient delivery vehicles to cross the blood–brain barrier…”
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Gene delivery targeted to the brain using an Angiopep-conjugated polyethyleneglycol-modified polyamidoamine dendrimer by Ke, Weilun, Shao, Kun, Huang, Rongqin, Han, Liang, Liu, Yang, Li, Jianfeng, Kuang, Yuyang, Ye, Liya, Lou, Jinning, Jiang, Chen

“…Abstract Angiopep targeting to the low-density lipoprotein receptor-related protein-1 (LRP1) was identified to exhibit high transcytosis capacity and…”
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Enhanced oral bioavailability of doxorubicin in a dendrimer drug delivery system by Ke, Weilun, Zhao, Yansong, Huang, Rongqin, Jiang, Chen, Pei, Yuanying

“…PAMAM dendrimers can permeate across intestinal epithelial barriers suggesting their potential as oral drug carriers. In the present study, we have developed a…”
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Recent Developments in CaCO3 Nano-Drug Delivery Systems: Advancing Biomedicine in Tumor Diagnosis and Treatment by Lin, Chenteng, Akhtar, Muhammad, Li, Yingjie, Ji, Min, Huang, Rongqin

“…Calcium carbonate (CaCO3), a natural common inorganic material with good biocompatibility, low toxicity, pH sensitivity, and low cost, has a widespread use in…”
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Targeted delivery of chlorotoxin-modified DNA-loaded nanoparticles to glioma via intravenous administration by Huang, Rongqin, Ke, Weilun, Han, Liang, Li, Jianfeng, Liu, Shuhuan, Jiang, Chen

“…Abstract Gene therapy offers great potential for brain glioma. However, therapeutic genes could not reach glioma spontaneously. A glioma-targeting gene…”
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CircPLXNA2 Affects the Proliferation and Apoptosis of Myoblast through circPLXNA2 / gga-miR-12207-5P / MDM4 Axis by Dong, Xu, Xing, Jiabao, Liu, Qingchun, Ye, Mao, Zhou, Zhen, Li, Yantao, Huang, Rongqin, Li, Zhenhui, Nie, Qinghua

“…CircRNAs are newly identified special endogenous RNA molecules that covalently close a loop by back-splicing with pre-mRNA. In the cytoplasm, circRNAs would…”
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Gene therapy using lactoferrin-modified nanoparticles in a rotenone-induced chronic Parkinson model by Huang, Rongqin, Ke, Weilun, Liu, Yang, Wu, Dongdong, Feng, Linyin, Jiang, Chen, Pei, Yuanying

“…Abstract Background Gene therapy is considered one of the most promising approaches to develop an effective treatment for Parkinson's disease (PD). The…”
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Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma by Wang, Shanshan, Reinhard, Sören, Li, Chengyi, Qian, Min, Jiang, Huiling, Du, Yilin, Lächelt, Ulrich, Lu, Weiyue, Wagner, Ernst, Huang, Rongqin

“…The effective treatment of glioma is largely hindered by the poor transfer of drug delivery systems across the blood-brain barrier (BBB) and the difficulty in…”
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Tumor-Targeted Fluorescence Imaging and Mechanisms of Tumor Cell-Derived Carbon Nanodots by Huo, Taotao, Li, Wenshuai, Liang, Dong, Huang, Rongqin

“…An ideal cancer diagnostic probe should possess precise tumor-targeted accumulation with negligible sojourn in normal tissues. Herein, tumor cell-derived…”
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The use of lactoferrin as a ligand for targeting the polyamidoamine-based gene delivery system to the brain by Huang, Rongqin, Ke, Weilun, Liu, Yang, Jiang, Chen, Pei, Yuanying

“…Abstract Development of an efficient gene vector is a key-limiting factor of brain gene therapy. In this study, lactoferrin (Lf), for the first time, was…”
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Targeted peptide-modified oxidized mesoporous carbon nanospheres for chemo-thermo combined therapy of ovarian cancer in vitro by Wang, Shanshan, Wu, Wei, Liu, Ying, Wang, Chunhui, Xu, Qing, Lv, Qianzhou, Huang, Rongqin, Li, Xiaoyu

“…Ovarian cancer remains one of serious hazards to human health due to many drawbacks of existing available treatment options. In this study, a multifunctional…”
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Receptor-Mediated Drug Delivery Systems Targeting to Glioma by Wang, Shanshan, Meng, Ying, Li, Chengyi, Qian, Min, Huang, Rongqin

“…Glioma has been considered to be the most frequent primary tumor within the central nervous system (CNS). The complexity of glioma, especially the existence of…”
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Transcriptome Data Revealed the circRNA-miRNA-mRNA Regulatory Network during the Proliferation and Differentiation of Myoblasts in Shitou Goose by Huang, Rongqin, Chen, Jiahui, Dong, Xu, Zhang, Xiquan, Luo, Wen

“…CircRNA, a recently characterized non-coding RNA (ncRNA) variant, functions as a molecular sponge, exerting regulatory control by binding to microRNA (miRNA)…”
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Antioxidant Cascade Nanoenzyme Antagonize Inflammatory Pain by Modulating MAPK/p‐65 Signaling Pathway by Ling, Yuejuan, Nie, Dekang, Huang, Yue, Deng, Mengyuan, Liu, Qianqian, Shi, Jinlong, Ouyang, Siguang, Yang, Yu, Deng, Song, Lu, Zhichao, Yang, Junling, Wang, Yi, Huang, Rongqin, Shi, Wei

“…Chronic pain has attracted wide interest because it is a major obstacle affecting the quality of life. Consequently, safe, efficient, and low‐addictive drugs…”
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Receptor-Targeted Carbon Nanodot Delivery through Polymer Caging and Click Chemistry-Supported LRP1 Ligand Attachment by Zhang, Fengrong, Benli-Hoppe, Teoman, Guo, Wei, Seidl, Johanna, Wang, Yi, Huang, Rongqin, Wagner, Ernst

“…Carbon nanodots present resistance to photobleaching, bright photoluminescence, and superior biocompatibility, making them highly promising for bioimaging…”
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