Search Results - "Huang, PL"

Targeted disruption of the neuronal nitric oxide synthase gene by Huang, P L, Dawson, T M, Bredt, D S, Snyder, S H, Fishman, M C

“…By homologous recombination, we have generated mice that lack the neuronal nitric oxide synthase (NOS) gene. Neuronal NOS expression and NADPH-diaphorase (NDP)…”
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A saturated map of common genetic variants associated with human height by Vedantam, Sailaja, Sidorenko, Julia, Raghavan, Sridharan, Spracklen, Cassandra N., Yin, Xianyong, Highland, Heather H., Ahluwalia, Tarunveer S., Bollepalli, Sailalitha, Chang, Li-Ching, Chang, Yi-Cheng, Dietl, Alexander, Dorajoo, Rajkumar, Forer, Lukas, Gao, Yan, Gordon, Scott D., Hindy, George, Huo, Shaofeng, Hwang, Mi Yeong, Isono, Masato, Jackson, Anne U., Kentistou, Katherine A., Kim, Han-Na, Kleber, Marcus E., Lee, Jong-Young, Lin, Honghuang, Lin, Shih-Yi, Lyssenko, Valeriya, Mahajan, Anubha, McDaid, Aaron F., Mercader, Josep M., Nethander, Maria, Noordam, Raymond, Pandit, Anita, Petersen, Liselotte V., Poveda, Alaitz, Pyarajan, Saiju, Rasheed, Asif, Shen, Botong, Shi, Jingchunzi, Smit, Roelof A. J., Tallapragada, Divya Sri Priyanka, van der Laan, Sander W., van Setten, Jessica, Wong, Andrew, Zimmermann, Martina E., Al-Mulla, Fahd, Bharadwaj, Dwaipayan, Boerwinkle, Eric, Borja, Judith B., Brumpton, Ben, Cheng, Ching-Yu, Christophersen, Ingrid E., Ciullo, Marina, Damrauer, Scott M., Dantoft, Thomas M., De Jager, Philip L., de Kleijn, Dominique P. V., Du, Shufa, Easton, Douglas F., Ferrucci, Luigi, Ford, Ian, Fornage, Myriam, Gieger, Christian, Haiman, Christopher, Hansen, Torben, Heckbert, Susan R., Hengstenberg, Christian, Hewitt, Alex W., Huang, Wei, Jin, Zi-Bing, Joshi, Peter K., Kim, Eung Kweon, Kirchhof, Paulus, Kolovou, Genovefa D., Lehtimäki, Terho, Li, Huaixing, Lin, Xu, Lind, Lars, McGue, Matt, Newton-Cheh, Christopher, Nielsen, Christopher S., Ohlsson, Claes, Pajukanta, Päivi, Penninx, Brenda W. J. H., Pramstaller, Peter P., Province, Michael A., Ripatti, Samuli, Roden, Dan M., Schmidt, Börge, Schmidt, Reinhold, Sims, Mario, Vitart, Veronique, Vollenweider, Peter, Wilson, James F., Yokota, Mitsuhiro, Zheng, Wei, Deloukas, Panos, Loos, Ruth J. F., Abecasis, Goncalo R., Okada, Yukinori

“…Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50% of phenotypic variation in human height, but identifying the…”
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HSD21 Relationships Between Census Tract-Level Social Determinants of Health and Cardiovascular Care Among Individuals Diagnosed With Breast Cancer by Huang, PL, MΜ, Mysore, Barr, B, Onukwugha, E

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The role of neuronal nitric oxide synthase in cocaine-induced conditioned place preference by Itzhak, Yossef, Martin, Julio L, Black, M Dean, Huang, Paul L

“…PREVIOUS studies suggested the involvement of the neuronal nitric oxide synthase (nNOS) in the development of sensitization to psychostimulants. In the present…”
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Lipopolysaccharide-induced diaphragmatic contractile dysfunction and sarcolemmal injury in mice lacking the neuronal nitric oxide synthase by COMTOIS, Alain S, BARREIRO, Esther, HUANG, Paul L, MARETTE, André, PERRAULT, Mylène, HUSSAIN, Sabah N. A

“…In this study we evaluated the role of the neuronal nitric oxide synthase (nNOS) in lipopolysaccharide (LPS)-induced diaphragmatic contractile dysfunction and…”
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Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice by Dawson, VL, Kizushi, VM, Huang, PL, Snyder, SH, Dawson, TM

“…In addition to its functions as a neuronal messenger molecule, nitric oxide (NO) has also been implicated in playing a major role in ischemic damage and…”
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Genital tuberculosis presenting as acute scrotum mimicking Fournier's gangrene by Pong, YH, Chang, CJ, Tsai, VFS, Tsai, DC, Tsai, JH, Lee, IC, Huang, PL

“…Genital tuberculosis usually presents as local symptoms such as lower abdominal pain and a sensation of scrotal bloating. We report a rare case of genital…”
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Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction by JIQIU CHEN, TUNG, Ching-Hsuan, ALLPORT, Jennifer R, SI CHEN, WEISSLEDER, Ralph, HUANG, Paul L

“…We used a molecular probe activated by protease cleavage to image expression of matrix metalloproteinases (MMPs) in the heart after myocardial infarction. We…”
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Predominant Role of Endothelial Nitric Oxide Synthase in Vascular Endothelial Growth Factor-Induced Angiogenesis and Vascular Permeability by Fukumura, Dai, Gohongi, Takeshi, Kadambi, Ananth, Izumi, Yotaro, Ang, Jennifer, Yun, Chae-Ok, Buerk, Donald G., Huang, Paul L., Jain, Rakesh K.

“…Nitric oxide (NO) plays a critical role in vascular endothelial growth factor (VEGF)-induced angiogenesis and vascular hyperpermeability. However, the relative…”
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Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia by TSUJI, Kiyoshi, AOKI, Toshiaki, TEJIMA, Emiri, ARAI, Ken, LEE, Sun-Ryung, ATOCHIN, Dmitriy N, HUANG, Paul L, XIAOYING WANG, MONTANER, Joan, LO, Eng H

“…Thrombolytic therapy with tissue plasminogen activator (tPA) in ischemic stroke is limited by increased risks of cerebral hemorrhage and brain injury. In part,…”
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Deletion of exon 6 of the neuronal nitric oxide synthase gene in mice results in hypogonadism and infertility by Gyurko, Robert, Leupen, Sarah, Huang, Paul L

“…Nitric oxide (NO) has been recognized as a modulator in reproductive functions, but it is not clear whether NO is required for fertility. The first line of…”
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In vivo imaging of proteolytic activity in atherosclerosis by JIQIU CHEN, TUNG, Ching-Hsuan, MAHMOOD, Umar, NTZIACHRISTOS, Vasilis, GYURKO, Robert, FISHMAN, Mark C, HUANG, Paul L, WEISSLEDER, Ralph

“…Atherosclerotic plaque rupture, the most important cause of acute cardiovascular incidents, has been strongly associated with vascular inflammation. On the…”
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NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels by Kashiwagi, Satoshi, Izumi, Yotaro, Gohongi, Takeshi, Demou, Zoe N, Xu, Lei, Huang, Paul L, Buerk, Donald G, Munn, Lance L, Jain, Rakesh K, Fukumura, Dai

“…NO has been shown to mediate angiogenesis; however, its role in vessel morphogenesis and maturation is not known. Using intravital microscopy, histological…”
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Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms by Hare, Joshua M, Barouch, Lili A, Harrison, Robert W, Skaf, Michel W, Rosas, Gisele O, Cappola, Thomas P, Kobeissi, Zoulficar A, Hobai, Ion A, Lemmon, Christopher A, Burnett, Arthur L, O'Rourke, Brian, Rodriguez, E. Rene, Huang, Paul L, Lima, João A. C, Berkowitz, Dan E

“…Subcellular localization of nitric oxide (NO) synthases with effector molecules is an important regulatory mechanism for NO signalling. In the heart, NO…”
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Accelerated atherosclerosis, aortic aneurysm formation, and ischemic heart disease in apolipoprotein E/endothelial nitric oxide synthase double-knockout mice by KUHLENCORDT, Peter J, GYURKO, Robert, HAN, Fred, SCHERRER-CROSBIE, Marielle, ARETZ, Thomas H, HAJJAR, Roger, PICARD, Michael H, HUANG, Paul L

“…To test whether deficiency in endothelial nitric oxide synthase (eNOS) affects atherosclerosis development, we compared lesion formation in apolipoprotein E…”
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Inducible Nitric-oxide Synthase Is an Important Contributor to Prolonged Protective Effects of Ischemic Preconditioning in the Mouse Kidney by Park, Kwon Moo, Byun, Ji-Yeon, Kramers, Cornelis, Kim, Jee In, Huang, Paul L., Bonventre, Joseph V.

“…Ischemic preconditioning renders the mouse kidney resistant to subsequent ischemia. Understanding the mechanisms responsible for ischemic preconditioning is…”
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Nitric oxide synthase modulates angiogenesis in response to tissue ischemia by Murohara, T, Asahara, T, Silver, M, Bauters, C, Masuda, H, Kalka, C, Kearney, M, Chen, D, Symes, J F, Fishman, M C, Huang, P L, Isner, J M

“…We tested the hypothesis that endothelial nitric oxide synthase (eNOS) modulates angiogenesis in two animal models in which therapeutic angiogenesis has been…”
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Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice by Amin-Hanjani, S, Stagliano, N E, Yamada, M, Huang, P L, Liao, J K, Moskowitz, M A

“…The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) lower serum cholesterol and decrease the incidence of stroke and…”
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Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes by Pulit, Sara L, Weng, Lu-Chen, McArdle, Patrick F, Trinquart, Ludovic, Choi, Seung Hoan, Mitchell, Braxton D, Rosand, Jonathan, de Bakker, Paul I W, Benjamin, Emelia J, Ellinor, Patrick T, Kittner, Steven J, Lubitz, Steven A, Anderson, Christopher D

“…We sought to assess whether genetic risk factors for atrial fibrillation (AF) can explain cardioembolic stroke risk. We evaluated genetic correlations between…”
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Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment by Lee-Huang, Sylvia, Zhang, Li, Lin Huang, Philip, Chang, Young-Tae, Huang, Paul L

“…We investigated the antiviral activity of olive leaf extract (OLE) preparations standardized by liquid chromatography-coupled mass spectrometry (LC-MS) against…”
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