Search Results - "Huang, Lotien Richard"
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Continuous Particle Separation through Deterministic Lateral Displacement
Published in Science (American Association for the Advancement of Science) (14-05-2004)“…We report on a microfluidic particle-separation device that makes use of the asymmetric bifurcation of laminar flow around obstacles. A particle chooses its…”
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Journal Article -
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A DNA prism for high-speed continuous fractionation of large DNA molecules
Published in Nature biotechnology (01-10-2002)“…The analysis and fractionation of large DNA molecules plays a key role in many genome projects. The standard method, pulsed-field gel electrophoresis (PFGE),…”
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Journal Article -
3
Tilted Brownian Ratchet for DNA Analysis
Published in Analytical chemistry (Washington) (15-12-2003)“…In this paper, we report a factor of 3 improvement in the resolution and a factor of 10 improvement in the speed of fractionation of ∼100-kb DNA molecules in…”
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Journal Article -
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Role of molecular size in ratchet fractionation
Published in Physical review letters (21-10-2002)“…We show the importance of finite particle size in microfluidic asymmetric continuous-flow diffusion arrays, specifically the critical nature of the particle…”
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Journal Article -
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Microfluidic devices for genomic analysis
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Dissertation -
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Microfluidic devices for genomic analysis
Published 01-01-2004“…Separation by size is a fundamental analytical and preparative technique in biology, medicine, chemistry, and industry. The fractionation of biological…”
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Dissertation -
7
A DNA prism for high-speed continuous fractionation of large DNA molecules
Published in Nature biotechnology (01-10-2002)“…The analysis and fractionation of large DNA molecules plays a key role in many genome projects. The standard method, pulsed-field gel electrophoresis (PFGE),…”
Get full text
Technical Report -
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A DNA prism: physical principles for optimizing a microfabricated DNA separation device
Published in Digest. International Electron Devices Meeting (2002)“…Recently, we reported a microfabricated "DNA prism" device that continuously sorts large DNA molecules (61 kilo-base pair to 209 kb) according to size in 15…”
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Conference Proceeding