Search Results - "Huang, Kun D."
-
1
Analysis of 1321 Eubacterium rectale genomes from metagenomes uncovers complex phylogeographic population structure and subspecies functional adaptations
Published in Genome Biology (08-06-2020)“…Eubacterium rectale is one of the most prevalent human gut bacteria, but its diversity and population genetics are not well understood because large-scale…”
Get full text
Journal Article -
2
Metagenomic analysis of ancient dental calculus reveals unexplored diversity of oral archaeal Methanobrevibacter
Published in Microbiome (30-09-2021)“…Dental calculus (mineralised dental plaque) preserves many types of microfossils and biomolecules, including microbial and host DNA, and ancient calculus are…”
Get full text
Journal Article -
3
MetaPhlAn 4 profiling of unknown species-level genome bins improves the characterization of diet-associated microbiome changes in mice
Published in Cell reports (Cambridge) (30-05-2023)“…Mouse models are key tools for investigating host-microbiome interactions. However, shotgun metagenomics can only profile a limited fraction of the mouse gut…”
Get full text
Journal Article -
4
Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4
Published in Nature biotechnology (01-11-2023)“…Metagenomic assembly enables new organism discovery from microbial communities, but it can only capture few abundant organisms from most metagenomes. Here we…”
Get full text
Journal Article -
5
The person-to-person transmission landscape of the gut and oral microbiomes
Published in Nature (London) (02-02-2023)“…The human microbiome is an integral component of the human body and a co-determinant of several health conditions 1 , 2 . However, the extent to which…”
Get full text
Journal Article -
6
The Prevotella copri Complex Comprises Four Distinct Clades Underrepresented in Westernized Populations
Published in Cell host & microbe (13-11-2019)“…Prevotella copri is a common human gut microbe that has been both positively and negatively associated with host health. In a cross-continent meta-analysis…”
Get full text
Journal Article -
7
Rates of Mutation and Recombination in Siphoviridae Phage Genome Evolution over Three Decades
Published in Molecular biology and evolution (01-05-2018)“…The evolution of asexual organisms is driven not only by the inheritance of genetic modification but also by the acquisition of foreign DNA. The contribution…”
Get full text
Journal Article -
8
Maternal and food microbial sources shape the infant microbiome of a rural Ethiopian population
Published in Current biology (22-05-2023)“…The human microbiome seeding starts at birth, when pioneer microbes are acquired mainly from the mother. Mode of delivery, antibiotic prophylaxis, and feeding…”
Get full text
Journal Article -
9
Hallstatt miners consumed blue cheese and beer during the Iron Age and retained a non-Westernized gut microbiome until the Baroque period
Published in Current biology (06-12-2021)“…We subjected human paleofeces dating from the Bronze Age to the Baroque period (18th century AD) to in-depth microscopic, metagenomic, and proteomic analyses…”
Get full text
Journal Article -
10
Extension of the Segatella copri complex to 13 species with distinct large extrachromosomal elements and associations with host conditions
Published in Cell host & microbe (08-11-2023)“…The Segatella copri (formerly Prevotella copri) complex (ScC) comprises taxa that are key members of the human gut microbiome. It was previously described to…”
Get full text
Journal Article -
11
Establishment of a non-Westernized gut microbiota in men who have sex with men is associated with sexual practices
Published in Cell reports. Medicine (19-03-2024)“…The human gut microbiota is influenced by various factors, including health status and environmental conditions, yet considerable inter-individual differences…”
Get full text
Journal Article -
12
Reconstruction of ancient microbial genomes from the human gut
Published in Nature (London) (10-06-2021)“…Loss of gut microbial diversity 1 – 6 in industrial populations is associated with chronic diseases 7 , underscoring the importance of studying our ancestral…”
Get full text
Journal Article -
13
Application of Ultrasonography in the Diagnosis and Management of Papillary Thyroid Microcarcinoma
Published in Advanced ultrasound in diagnosis and therapy (30-12-2020)“…Thyroid carcinoma is the most common malignant tumor of the endocrine system. Nearly 90% of thyroid carcinomas are papillary type, of which many are thyroid…”
Get full text
Journal Article -
14
Early Cardiovascular Disease After the Diagnosis of Systemic Sclerosis
Published in The American journal of medicine (01-03-2016)“…Abstract Purpose The purpose of this study is to assess risk and time trends of newly recorded myocardial infarction and stroke in cases with systemic…”
Get full text
Journal Article -
15
Use of Masquelet’s technique for treating the first metatarsophalangeal joint in cases of gout combined with a massive bone defect
Published in Foot and ankle surgery (01-04-2018)“…Highlights • To examine the safety and efficacy of Masquelet’s technique as a surgical method for treating the first metatarsophalangeal joint in cases of gout…”
Get full text
Journal Article -
16
Inhibition of Na-K-Cl cotransporter isoform 1 reduces lung injury induced by ischemia–reperfusion
Published in The Journal of thoracic and cardiovascular surgery (01-01-2017)“…Abstract Objectives Ischemia–reperfusion acute lung injury is characterized by increased vascular permeability, lung edema, and neutrophil sequestration…”
Get full text
Journal Article -
17
Functional Outcome in Acute Stroke Patients with Oropharyngeal Dysphagia after Swallowing Therapy
Published in Journal of stroke and cerebrovascular diseases (01-11-2014)“…Dysphagia after stroke is associated with mortality and increased pulmonary complications. Swallowing therapies may decrease pulmonary complications and…”
Get full text
Journal Article -
18
Derivation and validation of a scoring system for predicting nonalcoholic steatohepatitis in Taiwanese patients with severe obesity
Published in Surgery for obesity and related diseases (01-04-2017)“…Abstract Background Nonalcoholic steatohepatitis (NASH) is common in severely obese Asians and may progress to advanced liver disease. Although invasive, liver…”
Get full text
Journal Article -
19
Cancer Incidence Trend in Chinese Longevity Town Cenxi City from 2016 to 2020
Published in Zhongguo quanke yixue (01-11-2022)“…Background Along with the acceleration of population aging and the increase in average life expectancy, how to improve the quality of life of residents has…”
Get full text
Journal Article -
20
Hypercapnic acidosis prolongs survival of skin allografts
Published in The Journal of surgical research (01-05-2015)“…Abstract Background Evidence reveals that hypercapnic acidosis (HCA) modulates immune responses. However, the effect of HCA on allogenic skin graft rejection…”
Get full text
Journal Article