Search Results - "Huang, Kexin"

MolTrans: Molecular Interaction Transformer for drug–target interaction prediction by Huang, Kexin, Xiao, Cao, Glass, Lucas M, Sun, Jimeng

“…Abstract Motivation Drug–target interaction (DTI) prediction is a foundational task for in-silico drug discovery, which is costly and time-consuming due to the…”
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Building a knowledge graph to enable precision medicine by Chandak, Payal, Huang, Kexin, Zitnik, Marinka

“…Developing personalized diagnostic strategies and targeted treatments requires a deep understanding of disease biology and the ability to dissect the…”
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DeepPurpose: a deep learning library for drug–target interaction prediction by Huang, Kexin, Fu, Tianfan, Glass, Lucas M, Zitnik, Marinka, Xiao, Cao, Sun, Jimeng

“…Abstract Summary Accurate prediction of drug–target interactions (DTI) is crucial for drug discovery. Recently, deep learning (DL) models for show promising…”
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Preparation and characterization of carboxymethyl cellulose containing quaternized chitosan for potential drug carrier by Wang, Fang, Zhang, Qian, Huang, Kexin, Li, Jiarui, Wang, Kun, Zhang, Kai, Tang, Xinyue

“…[Display omitted] •CMC blended HACC composite hydrogel film with redox and pH responsive is designed.•CMC/HACC composite hydrogel film has good mechanical and…”
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Comparison study on different SOFC hybrid systems with zero-CO2 emission by Duan, Liqiang, Huang, Kexin, Zhang, Xiaoyuan, Yang, Yongping

“…Based on a traditional SOFC (solid oxide fuel cell) hybrid power system, three different SOFC hybrid power systems with zero-CO2 emission are proposed in this…”
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Experimental Study of the Response of Sheared E × B Flow to Varying Ion–Neutral Collisions by Zhang, Xiao, Liu, Yu, Lei, Jiuhou, Huang, Wenlong, Huang, Kexin, Jin, Rong

“…Abstract Partially ionized plasma is a common occurrence in astrophysical and space environments. The emergence and development of plasma instabilities are…”
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Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human by Wu, Jun, Boström, Pontus, Sparks, Lauren M., Ye, Li, Choi, Jang Hyun, Giang, An-Hoa, Khandekar, Melin, Virtanen, Kirsi A., Nuutila, Pirjo, Schaart, Gert, Huang, Kexin, Tu, Hua, van Marken Lichtenbelt, Wouter D., Hoeks, Joris, Enerbäck, Sven, Schrauwen, Patrick, Spiegelman, Bruce M.

“…Brown fat generates heat via the mitochondrial uncoupling protein UCP1, defending against hypothermia and obesity. Recent data suggest that there are two…”
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Existence of Electrostatic Ion Cyclotron Waves in a Laboratory Created E Region Ionospheric‐Like Plasma by Liu, Yu, Jin, Rong, Li, Minchi, Huang, Wenlong, Huang, Kexin, Jiang, Junnan, Yu, Pengcheng, Lei, Jiuhou

“…Molecular ions are relatively cold in the E region ionosphere; however, they can upwell to the magnetosphere during geomagnetically active times. Resonance…”
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Understanding the Relationship Between Shrinking Cities and Land Prices: Spatial Pattern, Effectiveness, and Policy Implications by Wang, Xiaohui, Peng, Li, Huang, Kexin, Deng, Wei

“…Urban shrinkage has emerged as a widespread phenomenon globally and has a significant impact on land, particularly in terms of land use and price. This study…”
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Inferring evolutionary trajectories from cross-sectional transcriptomic data to mirror lung adenocarcinoma progression by Huang, Kexin, Zhang, Yun, Gong, Haoran, Qiao, Zhengzheng, Wang, Tiangang, Zhao, Weiling, Huang, Liyu, Zhou, Xiaobo

“…Lung adenocarcinoma (LUAD) is a deadly tumor with dynamic evolutionary process. Although much endeavors have been made in identifying the temporal patterns of…”
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Generalized Additive Model Reveals Nonlinear Trade-Offs/Synergies between Relationships of Ecosystem Services for Mountainous Areas of Southwest China by Huang, Qi, Peng, Li, Huang, Kexin, Deng, Wei, Liu, Ying

“…Ecosystem services (ESs) are an essential link between ecosystems and human well-being, and trade-offs/synergies happen in ESs at different temporal and…”
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Research on blasting mechanism and blasting effect of aqueous media in open pit coal mines by Ding, Xiaohua, Liu, Xin, Ao, Zhongchen, Qin, Hao, Li, Xiaoshuang, Huang, Kexin, Xiao, Shuangshuang, Wu, Mao, Zhang, Donghua, Zhu, Chun

“…Surface coal mining procedures include piercing—blasting—mining and loading—transportation—discharging, blasting link exists due to the poor blasting effect…”
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Identifying the influence of disaster education on the risk perception of rural residents in geohazard-prone areas: A propensity score-matched study by Wang, Xiaohui, Peng, Li, Huang, Kexin, Deng, Wei

“…Improving the risk perception of rural residents is an important factor in disaster risk reduction (DRR) activities. For residents in geohazard-prone areas,…”
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A nomogram for individualized prediction of mild cognitive impairment in patients with subjective cognitive decline during physical examinations: a cross-sectional study by Zhong, Tangsheng, Dou, Le, Liu, Peiqi, Huang, Kexin, Wang, Yonghong, Chen, Li

“…To develop a nomogram for mild cognitive impairment (MCI) in patients with subjective cognitive decline (SCD) undergoing physical examinations in China. We…”
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A Non-Enzymatic Sensor Based on Fc-CHIT/CNT@Cu Nanohybrids for Electrochemical Detection of Glucose by Wang, Fang, Hu, Sheng, Shi, Fengna, Huang, Kexin, Li, Jiarui

“…Herein, a composite structure, consisting of Cu nanoparticles (NPs) deposited onto carbon nanotubes and modified with ferrocene-branched chitosan, was prepared…”
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Biomedical Big Data Technologies, Applications, and Challenges for Precision Medicine: A Review by Yang, Xue, Huang, Kexin, Yang, Dewei, Zhao, Weiling, Zhou, Xiaobo

“…The explosive growth of biomedical Big Data presents both significant opportunities and challenges in the realm of knowledge discovery and translational…”
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Expression, regulation, and function of atypical chemerin receptor CCRL2 on endothelial cells by Monnier, Justin, Lewén, Susanna, O'Hara, Edward, Huang, Kexin, Tu, Hua, Butcher, Eugene C, Zabel, Brian A

“…Chemokine (CC motif) receptor-like 2 (CCRL2) binds leukocyte chemoattractant chemerin and can regulate local levels of the attractant, but does not itself…”
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Comparative Transcriptome Analysis of Two Peach Rootstocks Uncovers the Effect of Gene Differential Expression on Nitrogen Use Efficiency by Chen, Qiuju, Lian, Min, Guo, Jian, Zhang, Binbin, Yang, Sankui, Huang, Kexin, Peng, Futian, Xiao, Yuansong

“…Nitrogen is an important nutrient element that limits plant growth and yield formation, but excessive nitrogen has negative effects on plants and the…”
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Integrating Landscape Connectivity and Natural-Anthropogenic Interaction to Understand Karst Vegetation Restoration: A Case Study of Guizhou Province, China by Huang, Kexin, Peng, Li, Wang, Xiaohui, Chen, Tiantian

“…Because of implementation of ecological projects, the restoration of vegetation not only changes the typological composition and spatial structure of the…”
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Deep learning to predict long-term mortality in patients requiring 7 days of mechanical ventilation by George, Naomi, Moseley, Edward, Eber, Rene, Siu, Jennifer, Samuel, Mathew, Yam, Jonathan, Huang, Kexin, Celi, Leo Anthony, Lindvall, Charlotta

“…Background Among patients with acute respiratory failure requiring prolonged mechanical ventilation, tracheostomies are typically placed after approximately 7…”
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