Search Results - "Huang, Junju"
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Transposable elements activation triggers necroptosis in mouse embryonic stem cells
Published in Cell death & disease (07-03-2023)“…Deficiency of the histone H3K9 methyltransferase SETDB1 induces RIPK3-dependent necroptosis in mouse embryonic stem cells (mESCs). However, how necroptosis…”
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Fast and Efficient Mouse Pluripotency Reprogramming Using a Chemically-Defined Medium
Published in Methods and protocols (24-03-2022)“…The reprogramming of somatic cells to obtain induced pluripotent stem cells (iPSCs) is an important biological and medical breakthrough, providing important…”
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Establishing national reference materials for genetic testing of cytochrome P450
Published in Pharmacogenetics and genomics (01-08-2024)“…Reference materials for in-vitro diagnostic reagents play a critical role in determining the quality of reagents and ensuring the accuracy of clinical test…”
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KMT2D deficiency leads to cellular developmental disorders and enhancer dysregulation in neural-crest-containing brain organoids
Published in Science bulletin (Beijing) (30-11-2024)“…[Display omitted] KMT2D, a H3K4me1 methyltransferase primarily regulating enhancers, is a leading cause of KABUKI syndrome. This multisystem disorder leads to…”
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