Search Results - "Huang, JuFang"

Integrated Bioinformatics-Based Identification and Validation of Neuroinflammation-Related Hub Genes in Primary Open-Angle Glaucoma by Ullah, Zakir, Tao, Yuanyuan, Huang, Jufang

“…Glaucoma is a leading cause of permanent blindness, affecting 80 million people worldwide. Recent studies have emphasized the importance of neuroinflammation…”
Get full text

The Application of MicroRNAs in Glaucoma Research: A Bibliometric and Visualized Analysis by Zhang, Ruqi, Tao, Yuanyuan, Huang, Jufang

“…Glaucoma is similar to a neurodegenerative disorder and leads to global irreversible loss of vision. Despite extensive research, the pathophysiological…”
Get full text

Hepatocellular Carcinoma Cell-Derived Exosomal miR-21-5p Induces Macrophage M2 Polarization by Targeting RhoB by Yu, Haiyang, Pan, Jing, Zheng, Siyue, Cai, Deyang, Luo, Aixiang, Xia, Zanxian, Huang, Jufang

“…M2-like polarized tumor-associated macrophages (TAMs) are the major component of infiltrating immune cells in hepatocellular carcinoma (HCC), which have been…”
Get full text

Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy by Rong, Rong, Xia, Xiaobo, Peng, Haiqin, Li, Haibo, You, Mengling, Liang, Zhuotao, Yao, Fei, Yao, Xueyan, Xiong, Kun, Huang, Jufang, Zhou, Rongrong, Ji, Dan

“…Radiation-induced optic neuropathy (RION) is a devastating complication following external beam radiation therapy (EBRT) that leads to acute vision loss. To…”
Get full text

Exploring Zika Virus Impact on Endothelial Permeability: Insights into Transcytosis Mechanisms and Vascular Leakage by Henrio Marcellin, Dama Faniriantsoa, Huang, Jufang

“…Treating brain disease is challenging, and the Zika virus (ZIKV) presents a unique obstacle due to its neuroinvasive nature. In this review, we discuss the…”
Get full text

Valdecoxib Protects against Cell Apoptosis Induced by Endoplasmic Reticulum Stress via the Inhibition of PERK-ATF4-CHOP Pathway in Experimental Glaucoma by Gao, Zhaolin, Li, Min, Yao, Fei, Xia, Xiaobo, Duan, Tianqi, Meng, Jingzhuo, Huang, Yanxia, He, Ye, Saro, Adonira, Huang, Jufang

“…The purpose of this study was to investigate the effects of valdecoxib on the retina in retinal ischemia-reperfusion injury (IRI) and R28 cells following…”
Get full text

Melatonin Alleviates Pyroptosis of Retinal Neurons Following Acute Intraocular Hypertension by Zhang, Yu, Huang, Yanxia, Guo, Limin, Zhang, Yun, Zhao, Mingxuan, Xue, Fuyao, Tan, Cheng, Huang, Jufang, Chen, Dan

“…Glaucoma is a multifactorial optic neuropathy progressively characterized by structural loss of Retinal Ganglion Cells (RGCs) and irreversible loss of vision…”
Get more information

Targeting microRNA-23a to inhibit glioma cell invasion via HOXD10 by Hu, Xing, Chen, Dan, Cui, Yanhui, Li, Zhiyuan, Huang, Jufang

“…Glioma is the most frequent primary brain tumor. Recently, the upregulation of microRNA (miR)-23a was found to be associated with glioma, but the molecular…”
Get full text

A bibliometric analysis of the application of stem cells in glaucoma research from 1999 to 2022 by Tao, Yuanyuan, Zhang, Qian, Meng, Ming, Huang, Jufang

“…Glaucoma, a neurodegenerative disease of the retina, is the leading cause of irreversible blindness. Stem cells have therapeutic potential for glaucoma…”
Get full text

Necroptosis contributes to methamphetamine-induced cytotoxicity in rat cortical neurons by Xiong, Kun, Liao, Huidan, Long, Lingling, Ding, Yanjun, Huang, Jufang, Yan, Jie

“…Necroptosis, a programmed necrosis, is involved in various types of neurodegenerative diseases. In this study, we investigated whether necroptosis contributed…”
Get full text

HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death by Saro, Adonira, Gao, Zhaolin, Kambey, Piniel Alphayo, Li, Min, Huang, Jufang

“…Human immunodeficiency virus-1 (HIV-1)-associated neurodegenerative disorder (HAND) is frequently reported in HIV-infected individuals. The gp120 envelope…”
Get full text

Model informed dose regimen optimizing in development of leritrelvir for the treatment of mild or moderate COVID-19 by Wang, Kun, Li, Haijun, Li, Youyun, Xu, Fengyan, Sun, Zhongyi, Yang, Yuting, Huang, Jufang, Chen, Xiaoxin

“…Leritrelvir (RAY1216) acts as a main protease inhibitor that hinders the cleavage of viral precursor proteins, thereby inhibiting virus replication of…”
Get full text

Microbiome Profiling Using Shotgun Metagenomic Sequencing Identified Unique Microorganisms in COVID-19 Patients With Altered Gut Microbiota by Li, Sijia, Yang, Siyuan, Zhou, Yuzheng, Disoma, Cyrollah, Dong, Zijun, Du, Ashuai, Zhang, Yongxing, Chen, Yong, Huang, Weiliang, Chen, Junru, Song, Deqiang, Chen, Zongpeng, Liu, Pinjia, Li, Shiqin, Zheng, Rong, Liu, Sixu, Razzaq, Aroona, Chen, Xuan, Tao, Siyi, Yu, Chengping, Feng, Tianxu, Liao, Wenyan, Peng, Yousong, Jiang, Taijiao, Huang, Jufang, Wu, Wei, Hu, Liqiang, Wang, Linghang, Li, Shanni, Xia, Zanxian

“…COVID-19 is mainly associated with respiratory distress syndrome, but a subset of patients often present gastrointestinal (GI) symptoms. Imbalances of gut…”
Get full text

Gestational stress induced differential expression of HDAC2 in male rat offspring hippocampus during development by Liao, Libin, Wang, Xueqin, Yao, Xueping, Zhang, Bin, Zhou, Lihong, Huang, Jufang

“…•Stress during pregnancy inhibits hippocampal HDAC2 expression in male rat offspring.•Gestational stress inhibits hippocampal HDAC2 expression in male rat…”
Get full text

Astrocyte derived TSP2 contributes to synaptic alteration and visual dysfunction in retinal ischemia/reperfusion injury by Hu, Tu, Meng, Shuhan, Zhang, Qianyue, Song, Shuang, Tan, Cheng, Huang, Jufang, Chen, Dan

“…Despite current intervention measures/therapies are able to ameliorate neuronal death following retinal injuries/diseases, the recovery of visual function…”
Get full text

Mixed lineage kinase domain-like protein induces RGC-5 necroptosis following elevated hydrostatic pressure by Liao, Lvshuang, Shang, Lei, Li, Na, Wang, Shuchao, Wang, Mi, Huang, Yanxia, Chen, Dan, Huang, Jufang, Xiong, Kun

“…Receptor-interacting protein 3 （RIP3） is an essential component of the necroptosis signaling path- way. Phosphorylation of its downstream target, mixed lineage…”
Get full text

HIV-Proteins-Associated CNS Neurotoxicity, Their Mediators, and Alternative Treatments by Saro, Adonira, Gao, Zhaolin, Kambey, Piniel Alphayo, Pielnaa, Paul, Marcellin, Dama Faniriantsoa Henrio, Luo, Aixiang, Zheng, Ruping, Huang, Zhongjun, Liao, Lvshuang, Zhao, Mingxuan, Suo, Liangpeng, Lu, Shuang, Li, Min, Cai, Deyang, Chen, Dan, Yu, Haiyang, Huang, Jufang

“…Human immunodeficiency virus (HIV)-infected people's livelihoods are gradually being prolonged with the use of combined antiretroviral therapy (ART)…”
Get full text

Novel role of TRPV2 in promoting the cytotoxicity of H2O2-mediated oxidative stress in Human hepatoma cells by Ma, Wenbo, Li, Caiyue, Yin, Shikui, Liu, Jingxin, Gao, Chao, Lin, Zuoxian, Huang, Rongqi, Huang, Jufang, Li, Zhiyuan

“…Oxidative stress is important for the initiation and progression of cancers, which confers the cells with a survival advantage by inducing oxidative adaption…”
Get full text

HIF-1α promotes kidney organoid vascularization and applications in disease modeling by Peng, Kexin, Xie, Wanqin, Wang, Tingting, Li, Yamei, de Dieu Habimana, Jean, Amissah, Obed Boadi, Huang, Jufang, Chen, Yong, Ni, Bin, Li, Zhiyuan

“…Kidney organoids derived from human pluripotent stem cells (HiPSCs) hold huge applications for drug screening, disease modeling, and cell transplanting…”
Get full text

Macroglia-derived thrombospondin 2 regulates alterations of presynaptic proteins of retinal neurons following elevated hydrostatic pressure by Wang, Shuchao, Hu, Tu, Wang, Zhen, Li, Na, Zhou, Lihong, Liao, Lvshuang, Wang, Mi, Liao, Libin, Wang, Hui, Zeng, Leping, Fan, Chunling, Zhou, Hongkang, Xiong, Kun, Huang, Jufang, Chen, Dan

“…Many studies on retinal injury and repair following elevated intraocular pressure suggest that the survival ratio of retinal neurons has been improved by…”
Get full text