Search Results - "Huang, Jinhu"
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Characterization of a Linezolid- and Vancomycin-Resistant Streptococcus suis Isolate That Harbors optrA and vanG Operons
Published in Frontiers in microbiology (10-09-2019)“…Linezolid and vancomycin are among the last-resort antimicrobial agents in the treatment of multidrug-resistant Gram-positive bacterial infections. Linezolid-…”
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The cadDX operon contributes to cadmium resistance, oxidative stress resistance, and virulence in zoonotic streptococci
Published in Veterinary research (Paris) (27-09-2024)“…Mobile genetic elements (MGEs) enable bacteria to acquire novel genes and traits. However, the functions of cargo genes within MGEs remain poorly understood…”
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Allicin affects the pharmacokinetics of sulfadiazine and florfenicol by downregulating the expression of jejunum P-gp and BCRP in broilers
Published in Poultry science (01-07-2022)“…Allicin, one of the main bioactive compounds in garlic, is an excellent feed additive. It is unknown whether allicin affects the expression of P-gp and BCRP, 2…”
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Inhibitory Effect of Berberine on Broiler P-glycoprotein Expression and Function: In Situ and In Vitro Studies
Published in International journal of molecular sciences (22-04-2019)“…Overcoming P-glycoprotein (P-gp) efflux is a strategy to improve the absorption and pharmacokinetics of its substrate drugs. Berberine inhibits P-gp and…”
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Evolution and Diversity of the Antimicrobial Resistance Associated Mobilome in Streptococcus suis : A Probable Mobile Genetic Elements Reservoir for Other Streptococci
Published in Frontiers in cellular and infection microbiology (07-10-2016)“…is a previously neglected, newly emerging multidrug-resistant zoonotic pathogen. Mobile genetic elements (MGEs) play a key role in intra- and interspecies…”
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Horizontal Transfer of Different erm (B)-Carrying Mobile Elements Among Streptococcus suis Strains With Different Serotypes
Published in Frontiers in microbiology (26-03-2021)“…Macrolide-resistant is highly prevalent worldwide. The acquisition of the (B) gene mediated by mobile genetic elements (MGEs) in particular integrative and…”
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Relevance of Breast Cancer Resistance Protein to Pharmacokinetics of Florfenicol in Chickens: A Perspective from In Vivo and In Vitro Studies
Published in International journal of molecular sciences (15-10-2018)“…Florfenicol (FFC) is a valuable synthetic fluorinated derivative of thiamphenicol widely used to treat infectious diseases in food animals. The aims of the…”
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Selenomethionine and Allicin Synergistically Mitigate Intestinal Oxidative Injury by Activating the Nrf2 Pathway
Published in Toxics (Basel) (30-09-2024)“…Oxidative stress frequently contributes to intestinal barrier injury in animals and humans. It was reported that both Selenomethionine (SeMet) and allicin…”
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Coexistence of blaNDM–5 and tet(X4) in international high-risk Escherichia coli clone ST648 of human origin in China
Published in Frontiers in microbiology (10-11-2022)“…The emergence of pathogens is conferring resistance to last-resort therapies such as tigecycline, colistin, and carbapenems, limiting the therapeutic options,…”
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Abcb1 in Pigs: Molecular cloning, tissues distribution, functional analysis, and its effect on pharmacokinetics of enrofloxacin
Published in Scientific reports (30-08-2016)“…P-glycoprotein (P-gp) is one of the best-known ATP-dependent efflux transporters, contributing to differences in pharmacokinetics and drug-drug interactions…”
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11
Various Mobile Genetic Elements Involved in the Dissemination of the Phenicol-Oxazolidinone Resistance Gene optrA in the Zoonotic Pathogen Streptococcus suis: a Nonignorable Risk to Public Health
Published in Microbiology spectrum (15-06-2023)“…The rapid increase of phenicol-oxazolidinone (PhO) resistance in Streptococcus suis due to transferable resistance gene is a matter of concern. However,…”
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Effect of high-copper diet on transference of blaCTX−M genes among Escherichia coli strains in rats' intestine
Published in Frontiers in veterinary science (09-03-2023)“…Both ceftiofur (CTO) and high copper are widely utilized in animal production in China, and the occurrence of CTX-M-carrying Escherichia coli in food-producing…”
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13
Small clone dissemination of tmexCD1-toprJ1–carrying Klebsiella pneumoniae isolates in a chicken farm
Published in Journal of global antimicrobial resistance. (01-06-2022)“…Tigecycline is one of the last-resort treatments against multidrug-resistant (MDR) Gram-negative bacteria. Recently, a novel efflux pump gene cluster…”
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14
Potential Hepatoprotective Effects of Allicin on Carbon Tetrachloride-Induced Acute Liver Injury in Mice by Inhibiting Oxidative Stress, Inflammation, and Apoptosis
Published in Toxics (Basel) (01-05-2024)“…The global burden of liver disease is enormous, which highlights the need for effective hepatoprotective agents. It was reported that allicin exhibits…”
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15
Cloning and Transcriptional Activity Analysis of the Porcine Abcb1 Gene Promoter: Transcription Factor Sp1 Regulates the Expression of Porcine Abcb1
Published in Frontiers in pharmacology (04-05-2018)“…P-Glycoprotein (P-gp, Abcb1) plays a crucial role in drug disposition and functions by hydrolyzing ATP. However, little is known about the regulatory elements…”
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Overexpression of an ABC transporter and mutations of GyrA, GyrB, and ParC in contributing to high-level ciprofloxacin resistance in Streptococcus suis type 2
Published in BioScience Trends (01-01-2014)“…Streptococcus suis is a pathogen of zoonotic diseases. Moreover, the emergence of fluoro-quinolones (FQs) resistance in this pathogen has severe consequences…”
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Detection of Class 1 and 2 Integrons, β-Lactamase Genes and Molecular Characterization of Sulfonamide Resistance in Escherichia coli Isolates Recovered from Poultry in China
Published in Pakistan veterinary journal (01-01-2013)“…This study aimed to detect integrons, β-lactamase genes and to characterize sulfonamide resistant E. coli isolates recovered from poultry. All the isolates…”
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Efflux Pump, Methylation and Mutations in the 23S rRNA Genes Contributing to the Development of Macrolide Resistance in Streptococcus suis Isolated from Infected Human and Swine in China
Published in Pakistan veterinary journal (01-01-2014)“…Streptococcus suis is one of the major etiologic agents of contagious infections in swine and is also emerged as a zoonotic agent. A recent large scale…”
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Emergence of plasmid-mediated oxazolidinone resistance gene poxtA from CC17 Enterococcus faecium of pig origin
Published in Journal of antimicrobial chemotherapy (01-09-2019)“…Abstract Objectives To characterize the oxazolidinone resistance gene poxtA on broad-host-range Inc18 plasmids from CC17 Enterococcus faecium of pig origin…”
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Retrospective analysis of genome sequences revealed the wide dissemination of optrA in Gram-positive bacteria
Published in Journal of antimicrobial chemotherapy (01-02-2017)Get full text
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