Search Results - "Huang, Huoqiang"
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The Prediction of LptA and LptC Protein-Protein Interactions and Virtual Screening for Potential Inhibitors
Published in Molecules (Basel, Switzerland) (01-04-2024)“…Antibiotic resistance in Gram-negative bacteria remains one of the most pressing challenges to global public health. Blocking the transportation of…”
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3D QSAR studies on ketoamides of human cathepsin K inhibitors based on two different alignment methods
Published in European journal of medicinal chemistry (01-02-2010)“…Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were performed on 64 ketoamides as human cathepsin…”
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3D-QSAR study of sulfonamide inhibitors of human carbonic anhydrase II
Published in European journal of medicinal chemistry (01-03-2007)“…3D-QSAR models of Comparative of Molecular Field Analysis (CoMFA) and Comparative of Molecular Similarity Indices Analysis (CoMSIA) of 61 potent carbonic…”
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Screening and docking studies of natural phenolic inhibitors of carbonic anhydrase II
Published in Science China. Chemistry (01-03-2009)“…Carbonic anhydrase II (CA II) is an important enzyme complex with Zn2+, which is involved in many physiological and pathological processes, such as…”
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Discovery of 2,4-diphenyl-substituted thiazole derivatives as PRMT1 inhibitors and investigation of their anti-cervical cancer effects
Published in Bioorganic & medicinal chemistry (07-09-2023)“…A novel PRMT1 inhibitor ZJG51 exhibits a significant anti cervical cancer activity, inhibiting the proliferation and migration of HeLa cells in a low…”
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Innovative method for the enrichment of high‐polarity bioactive molecules present at low concentrations in complex matrices
Published in Journal of separation science (01-02-2017)“…Ginsenoside Rg1 is a valuable bioactive molecule but its high polarity and low concentration in complex mixtures makes it a challenge to separate Ginsenoside…”
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3D-QSAR and docking studies of aldehyde inhibitors of human cathepsin K
Published in Bioorganic & medicinal chemistry (15-04-2006)“…The genetic algorithm of GOLD2.2 has been employed to position 59 aldehyde compounds into the active sites of CatK to determine the probable binding…”
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Isoprenoids and phenylpropanoids from Saussurea deltoidea
Published in Zhongguo zhongyao zazhi (01-08-2011)“…To investigate the chemical constituents of Saussurea deltoidea, 10 compounds were isolated from the title plant by various chromatography methods such as…”
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Studies on chemical constituents in fruit of Alpinia oxyphylla
Published in Zhongguo zhongyao zazhi (01-04-2009)“…To study the chemical constituents in fruit of Alpinia oxyphylla and their cytotoxicities on cancer cell lines. Compounds were isolated and purified by various…”
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