Search Results - "Huang, Huichao"
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A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma
Published in Cell death & disease (03-02-2020)“…Abnormal expression of the E3 ubiquitin ligase A20 has been found in some malignant cancers, including hepatocellular carcinoma (HCC). Here, we discovered that…”
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Lactylation-Related Gene Signature Effectively Predicts Prognosis and Treatment Responsiveness in Hepatocellular Carcinoma
Published in Pharmaceuticals (Basel, Switzerland) (25-04-2023)“…Hepatocellular carcinoma (HCC) is a malignant tumor associated with high morbidity and mortality. Therefore, it is of great importance to develop effective…”
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Identification and Validation of a Novel Prognostic Signature Based on Ferroptosis-Related Genes in Ovarian Cancer
Published in Vaccines (Basel) (17-01-2023)“…Ovarian cancer is the most lethal gynecological tumor, with a poor prognosis due to the lack of early symptoms, resistance to chemotherapy, and recurrence…”
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Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells
Published in iScience (19-01-2024)“…Aerobic glycolysis is a pivotal hallmark of cancers, including colorectal cancer. Evidence shows glycolytic enzymes are regulated by post-translational…”
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Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer
Published in Clinical & experimental metastasis (01-08-2020)“…MACC1 (metastasis associated in colon cancer 1) is a key driver that induces metastasis in colon cancer. However, the mechanisms by which MACC1 expression is…”
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NiAl-Layer double hydroxide loading on MXenes nanosheets with boehmite-assisted for improved electrochemical performance
Published in Ionics (01-06-2023)“…MXene materials with high specific surface area and conductivity have received extensive attention in energy storage fields. In consideration of the…”
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Research on the mechanical performance of windshield glass for rail vehicles under gravel impact loadings
Published in Results in engineering (01-09-2024)“…This study aims to experimentally and numerically explore the bearing capacity of windshield glass for rail vehicles under projectile impact by gravel along…”
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Correction to: Mass spectrometry-based proteomic capture of proteins bound to the MACC1 promoter in colon cancer
Published in Clinical & experimental metastasis (01-12-2020)“…In the original publication of the article, Acknowledgements section was published incorrectly. The correct Acknowledgements is given in this Correction…”
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Suberoylanilide Hydroxamic Acid (SAHA) Treatment Reveals Crosstalk Among Proteome, Phosphoproteome, and Acetylome in Nasopharyngeal Carcinoma Cells
Published in Frontiers in genetics (03-05-2022)“…Suberoylanilide hydroxamic acid (SAHA), a famous histone deacetylase (HDAC) inhibitor, has been utilized in clinical treatment for cutaneous T-cell lymphoma…”
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Afatinib Reverses EMT via Inhibiting CD44-Stat3 Axis to Promote Radiosensitivity in Nasopharyngeal Carcinoma
Published in Pharmaceuticals (Basel, Switzerland) (27-12-2022)“…Afatinib, a second-generation tyrosine kinase inhibitor (TKI), exerts its radiosensitive effects in nasopharyngeal carcinoma (NPC). However, the detailed…”
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Species-Specific Deamidation of RIG-I Reveals Collaborative Action between Viral and Cellular Deamidases in HSV-1 Lytic Replication
Published in mBio (30-03-2021)“…Retinoic acid-inducible gene I (RIG-I) is a sensor that recognizes cytosolic double-stranded RNA derived from microbes to induce host immune response. Viruses,…”
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Dissection of Anti-tumor Activity of Histone Deacetylase Inhibitor SAHA in Nasopharyngeal Carcinoma Cells via Quantitative Phosphoproteomics
Published in Frontiers in cell and developmental biology (26-11-2020)“…Suberoylanilide hydroxamic acid (SAHA), a pan HDAC inhibitor, has been approved by the Food and Drug Administration (FDA) to treat cutaneous T cell lymphoma…”
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Quantitative proteomic profiling of tumor-associated vascular endothelial cells in colorectal cancer
Published in Biology open (2019)“…To investigate the global proteomic profiles of vascular endothelial cells (VECs) in the tumor microenvironment and antiangiogenic therapy for colorectal…”
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Integrating network pharmacology with microRNA microarray analysis to identify the role of miRNAs in thrombosis treated by the Dahuang Zhechong pill
Published in Computers in biology and medicine (01-05-2024)“…Thrombotic diseases are the leading causes of death worldwide, urging for improvements in treatment strategies. Dahuang Zhechong pill (DHZCP) is a traditional…”
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Prediction method of impact deformation mode based on multimodal fusion with point cloud sequences: Applied to thin-walled structures
Published in Advanced engineering informatics (01-01-2024)“…One of the challenges in solving the structural crashworthiness optimisation problem under impact deformation constraints is to construct an efficient and…”
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Recognition and optimisation method of impact deformation patterns based on point cloud and deep clustering: Applied to thin-walled tubes
Published in Journal of industrial information integration (01-07-2024)“…The recognition and clustering of deformation modes are key to constructing impact deformation constraints for thin-walled structures. This paper transforms…”
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Proteomics Profiling Reveals the Molecular Signatures and Potential Therapeutic Targets of Human Nasopharyngeal Carcinoma
Published in Molecular & cellular proteomics (01-06-2023)“…Nasopharyngeal carcinoma (NPC), a malignant tumor distinctly characterized by ethnic and geographic distribution, is highly prevalent in Southern China and…”
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DNA methylation-mediated silencing of Neuronatin promotes hepatocellular carcinoma proliferation through the PI3K-Akt signaling pathway
Published in Life sciences (1973) (01-01-2023)“…To explore the methylation status, function, and underlying mechanism of the imprinted gene Neuronatin (NNAT) in hepatocellular carcinoma (HCC) progression…”
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Discovery of a novel AR/HDAC6 dual inhibitor for prostate cancer treatment
Published in Aging (Albany, NY.) (15-03-2021)“…Androgen receptor (AR) and histone deacetylase 6 (HDAC6) are important targets for cancer therapy. Given that both AR antagonists and HDAC6 inhibitors modulate…”
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Postoperative leukocyte counts as a surrogate for surgical stress response in matched robot- and video-assisted thoracoscopic surgery cohorts of patients: A preliminary report
Published in Journal of robotic surgery (17-04-2024)“…The objective is to preliminary evaluated postoperative leukocyte counts as a surrogate for the surgical stress response in NSCLC patients who underwent RATS…”
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