Search Results - "Huang, Huarong"
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The Inflammatory Bowel Disease-Associated Autophagy Gene Atg16L1T300A Acts as a Dominant Negative Variant in Mice
Published in The Journal of immunology (1950) (15-03-2017)“…The basis of the increased risk for Crohn's disease conferred by the polymorphism is incompletely understood. An important step forward came from the recent…”
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An Atomic Force Microscope Study Revealed Two Mechanisms in the Effect of Anticancer Drugs on Rate-Dependent Young's Modulus of Human Prostate Cancer Cells
Published in PloS one (01-05-2015)“…Mechanical properties of cells have been recognized as a biomarker for cellular cytoskeletal organization. As chemical treatments lead to cell cytoskeletal…”
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3
Asperterpenoid A, a New Sesterterpenoid as an Inhibitor of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B from the Culture of Aspergillus sp. 16-5c
Published in Organic letters (15-02-2013)“…Asperterpenoid A (1), a novel sesterterpenoid with a new carbon skeleton, has been isolated from a mangrove endophytic fungus Aspergillus sp. 16-5c. Its…”
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4
miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia
Published in Neurobiology of disease (01-04-2010)“…Abstract Dysfunction of the microRNA (miR) network has been emerging as a major regulator in neurological diseases. However, little is known about the…”
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5
Combination of α-Tomatine and Curcumin Inhibits Growth and Induces Apoptosis in Human Prostate Cancer Cells
Published in PloS one (02-12-2015)“…α-Tomatine is a glycoalkaloid found in tomatoes and curcumin is a major yellow pigment of turmeric. In the present study, the combined effect of these two…”
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Combined effects of atorvastatin and aspirin on growth and apoptosis in human prostate cancer cells
Published in Oncology reports (01-02-2017)“…Epidemiologic studies indicate the use of either statins or aspirin have beneficial effects in prostate cancer patients. The present study was undertaken to…”
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7
miR-10a Contributes to Retinoid Acid-induced Smooth Muscle Cell Differentiation
Published in The Journal of biological chemistry (26-03-2010)“…MicroRNAs (miRs) have been reported to play a critical role in muscle differentiation and function. The purpose of this study is to determine the role of miRs…”
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Atorvastatin and Caffeine in Combination Regulates Apoptosis, Migration, Invasion and Tumorspheres of Prostate Cancer Cells
Published in Pathology oncology research (01-01-2020)“…Atorvastatin is the most prescribed cholesterol-lowering statin, while caffeine enhances chemo-sensitivity and induces apoptosis of tumor cells through its DNA…”
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9
Antagonistic Peptides That Specifically Bind to the First and Second Extracellular Loops of CCR5 and Anti-IL-23p19 Antibody Reduce Airway Inflammation by Suppressing the IL-23/Th17 Signaling Pathway
Published in Mediators of inflammation (2020)“…Asthma is a heterogeneous chronic inflammatory disorder of the airways with a complex etiology, which involves a variety of cells and cellular components…”
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10
E-protein regulatory network links TCR signaling to effector Treg cell differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (05-03-2019)“…T cell antigen receptor (TCR) signaling is essential for the differentiation and maintenance of effector regulatory T (Treg) cells. However, the contribution…”
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Ablation of the Sox11 Gene Results in Clefting of the Secondary Palate Resembling the Pierre Robin Sequence
Published in The Journal of biological chemistry (25-03-2016)“…Mouse gene inactivation has shown that the transcription factor Sox11 is required for mouse palatogenesis. However, whether Sox11 is primarily involved in the…”
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12
Effect of an Antagonistic Peptide of CCR5 on the Expression of Autophagy-related Genes and β-Arrestin 2 in Lung Tissues of Asthmatic Mice
Published in Allergy, asthma & immunology research (01-01-2021)“…The mechanisms of CC chemokine receptor 5 (CCR5) in the process of autophagy remain unknown. In this study, we examined the role of HY peptide, which is an…”
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13
Thioredoxin A Is Essential for Motility and Contributes to Host Infection of Listeria monocytogenes via Redox Interactions
Published in Frontiers in cellular and infection microbiology (28-06-2017)“…Microbes employ the thioredoxin system to defend against oxidative stress and ensure correct disulfide bonding to maintain protein function. has been shown to…”
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14
Eriocitrin in combination with resveratrol ameliorates LPS-induced inflammation in RAW264.7 cells and relieves TPA-induced mouse ear edema
Published in Journal of functional foods (01-05-2019)“…[Display omitted] Eriocitrin is a flavonoid that is isolated from orange peel. Resveratrol is a polyphenol compound, which is present in various fruits, such…”
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15
Combination of diethyldithiocarbamate with 12-O-tetradecanoyl phorbol-13-acetate inhibits the growth of human myeloid leukemia HL-60 cells in vitro and in xenograft model
Published in Bioscience, biotechnology, and biochemistry (02-10-2020)“…12-O-tetradecanoylphorbol-13-acetate (TPA), is a major active constituent of the seed oil of Croton tiglium L., has pharmacological activity for the treatment…”
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Pleural IFN-γ release assay combined with biomarkers distinguished effectively tuberculosis from malignant pleural effusion
Published in BMC infectious diseases (16-01-2019)“…Tuberculosis (TB) remains a major public health concern on a global scale, especially in developing nations. So far, no formal guidelines are available for the…”
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17
Adaptive molecular evolution of MC1R gene reveals the evidence for positive diversifying selection in indigenous goat populations
Published in Ecology and evolution (01-07-2017)“…Detecting signatures of selection can provide a new insight into the mechanism of contemporary breeding and artificial selection and further reveal the causal…”
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18
A triple combination of atorvastatin, celecoxib and tipifarnib strongly inhibits pancreatic cancer cells and xenograft pancreatic tumors
Published in International journal of oncology (01-06-2014)“…Because K-Ras mutation and cyclooxygenase-2 (COX-2) overexpression are hallmarks of majority of pancreatic cancer patients, an approach to inhibit the…”
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Andrographolide induce human embryonic stem cell apoptosis by oxidative stress response
Published in Molecular & cellular toxicology (01-04-2019)“…Backgrounds The anti-inflammatory effect of andrographolide is widely accepted; however, its exact role in reproductive toxicity requires further elucidation…”
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Cyclic Peptides from an Endophytic Fungus Obtained from a Mangrove Leaf (Kandelia candel)
Published in Journal of natural products (Washington, D.C.) (01-11-2007)“…Two new cyclic depsipeptides, 1962A (1) and 1962B (2), along with the three known cyclodipeptides cyclo-(Leu-Tyr) (3), cyclo-(Phe-Gly) (4), and cyclo-(Leu-Leu)…”
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