Search Results - "Huang, Hsien‐Da"

Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways by Weiberg, Arne, Wang, Ming, Lin, Feng-Mao, Zhao, Hongwei, Zhang, Znihong, Kaloshian, Isgouhi, Huang, Hsien-Da, Jin, Hailing

“…Botrytis cinerea, the causative agent of gray mold disease, is an aggressive fungal pathogen that infects more than 200 plant species. Here, we show that some…”
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miRTarBase 2020: updates to the experimentally validated microRNA–target interaction database by Huang, Hsi-Yuan, Lin, Yang-Chi-Dung, Li, Jing, Huang, Kai-Yao, Shrestha, Sirjana, Hong, Hsiao-Chin, Tang, Yun, Chen, Yi-Gang, Jin, Chen-Nan, Yu, Yuan, Xu, Jia-Tong, Li, Yue-Ming, Cai, Xiao-Xuan, Zhou, Zhen-Yu, Chen, Xiao-Hang, Pei, Yuan-Yuan, Hu, Liang, Su, Jin-Jiang, Cui, Shi-Dong, Wang, Fei, Xie, Yue-Yang, Ding, Si-Yuan, Luo, Meng-Fan, Chou, Chih-Hung, Chang, Nai-Wen, Chen, Kai-Wen, Cheng, Yu-Hsiang, Wan, Xin-Hong, Hsu, Wen-Lian, Lee, Tzong-Yi, Wei, Feng-Xiang, Huang, Hsien-Da

“…Abstract MicroRNAs (miRNAs) are small non-coding RNAs (typically consisting of 18–25 nucleotides) that negatively control expression of target genes at the…”
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miRTarBase update 2022: an informative resource for experimentally validated miRNA–target interactions by Huang, Hsi-Yuan, Lin, Yang-Chi-Dung, Cui, Shidong, Huang, Yixian, Tang, Yun, Xu, Jiatong, Bao, Jiayang, Li, Yulin, Wen, Jia, Zuo, Huali, Wang, Weijuan, Li, Jing, Ni, Jie, Ruan, Yini, Li, Liping, Chen, Yidan, Xie, Yueyang, Zhu, Zihao, Cai, Xiaoxuan, Chen, Xinyi, Yao, Lantian, Chen, Yigang, Luo, Yijun, LuXu, Shupeng, Luo, Mengqi, Chiu, Chih-Min, Ma, Kun, Zhu, Lizhe, Cheng, Gui-Juan, Bai, Chen, Chiang, Ying-Chih, Wang, Liping, Wei, Fengxiang, Lee, Tzong-Yi, Huang, Hsien-Da

“…Abstract MicroRNAs (miRNAs) are noncoding RNAs with 18–26 nucleotides; they pair with target mRNAs to regulate gene expression and produce significant changes…”
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dbPTM in 2019: exploring disease association and cross-talk of post-translational modifications by Huang, Kai-Yao, Lee, Tzong-Yi, Kao, Hui-Ju, Ma, Chen-Tse, Lee, Chao-Chun, Lin, Tsai-Hsuan, Chang, Wen-Chi, Huang, Hsien-Da

“…Abstract The dbPTM (http://dbPTM.mbc.nctu.edu.tw/) has been maintained for over 10 years with the aim to provide functional and structural analyses for…”
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MethHC: a database of DNA methylation and gene expression in human cancer by Huang, Wei-Yun, Hsu, Sheng-Da, Huang, Hsi-Yuan, Sun, Yi-Ming, Chou, Chih-Hung, Weng, Shun-Long, Huang, Hsien-Da

“…We present MethHC (http://MethHC.mbc.nctu.edu.tw), a database comprising a systematic integration of a large collection of DNA methylation data and…”
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Bidirectional cross-kingdom RNAi and fungal uptake of external RNAs confer plant protection by Wang, Ming, Weiberg, Arne, Lin, Feng-Mao, Thomma, Bart P. H. J., Huang, Hsien-Da, Jin, Hailing

“…Aggressive fungal pathogens such as Botrytis and Verticillium spp. cause severe crop losses worldwide. We recently discovered that Botrytis cinerea delivers…”
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miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database by Chou, Chih-Hung, Chang, Nai-Wen, Shrestha, Sirjana, Hsu, Sheng-Da, Lin, Yu-Ling, Lee, Wei-Hsiang, Yang, Chi-Dung, Hong, Hsiao-Chin, Wei, Ting-Yen, Tu, Siang-Jyun, Tsai, Tzi-Ren, Ho, Shu-Yi, Jian, Ting-Yan, Wu, Hsin-Yi, Chen, Pin-Rong, Lin, Nai-Chieh, Huang, Hsin-Tzu, Yang, Tzu-Ling, Pai, Chung-Yuan, Tai, Chun-San, Chen, Wen-Liang, Huang, Chia-Yen, Liu, Chun-Chi, Weng, Shun-Long, Liao, Kuang-Wen, Hsu, Wen-Lian, Huang, Hsien-Da

“…MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which negatively regulate the gene expression at the post-transcriptional level…”
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Mechanical stretch induces hair regeneration through the alternative activation of macrophages by Chu, Szu-Ying, Chou, Chih-Hung, Huang, Hsien-Da, Yen, Meng-Hua, Hong, Hsiao-Chin, Chao, Po-Han, Wang, Yu-Hsuan, Chen, Po-Yu, Nian, Shi-Xin, Chen, Yu-Ru, Liou, Li-Ying, Liu, Yu-Chen, Chen, Hui-Mei, Lin, Feng-Mao, Chang, Yun-Ting, Chen, Chih-Chiang, Lee, Oscar K.

“…Tissues and cells in organism are continuously exposed to complex mechanical cues from the environment. Mechanical stimulations affect cell proliferation,…”
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PlantPAN 2.0: an update of plant promoter analysis navigator for reconstructing transcriptional regulatory networks in plants by Chow, Chi-Nga, Zheng, Han-Qin, Wu, Nai-Yun, Chien, Chia-Hung, Huang, Hsien-Da, Lee, Tzong-Yi, Chiang-Hsieh, Yi-Fan, Hou, Ping-Fu, Yang, Tien-Yi, Chang, Wen-Chi

“…Transcription factors (TFs) are sequence-specific DNA-binding proteins acting as critical regulators of gene expression. The Plant Promoter Analysis Navigator…”
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miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions by Hsu, Sheng-Da, Tseng, Yu-Ting, Shrestha, Sirjana, Lin, Yu-Ling, Khaleel, Anas, Chou, Chih-Hung, Chu, Chao-Fang, Huang, Hsi-Yuan, Lin, Ching-Min, Ho, Shu-Yi, Jian, Ting-Yan, Lin, Feng-Mao, Chang, Tzu-Hao, Weng, Shun-Long, Liao, Kuang-Wen, Liao, I-En, Liu, Chun-Chi, Huang, Hsien-Da

“…MicroRNAs (miRNAs) are small non-coding RNA molecules capable of negatively regulating gene expression to control many cellular mechanisms. The miRTarBase…”
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An enhanced computational platform for investigating the roles of regulatory RNA and for identifying functional RNA motifs by Chang, Tzu-Hao, Huang, Hsi-Yuan, Hsu, Justin Bo-Kai, Weng, Shun-Long, Horng, Jorng-Tzong, Huang, Hsien-Da

“…Functional RNA molecules participate in numerous biological processes, ranging from gene regulation to protein synthesis. Analysis of functional RNA motifs and…”
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MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis by Tsai, Wei-Chih, Hsu, Sheng-Da, Hsu, Chu-Sui, Lai, Tsung-Ching, Chen, Shu-Jen, Shen, Roger, Huang, Yi, Chen, Hua-Chien, Lee, Chien-Hsin, Tsai, Ting-Fen, Hsu, Ming-Ta, Wu, Jaw-Ching, Huang, Hsien-Da, Shiao, Ming-Shi, Hsiao, Michael, Tsou, Ann-Ping

“…MicroRNA-122 (miR-122), which accounts for 70% of the liver's total miRNAs, plays a pivotal role in the liver. However, its intrinsic physiological roles…”
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dbPTM 2016: 10-year anniversary of a resource for post-translational modification of proteins by Huang, Kai-Yao, Su, Min-Gang, Kao, Hui-Ju, Hsieh, Yun-Chung, Jhong, Jhih-Hua, Cheng, Kuang-Hao, Huang, Hsien-Da, Lee, Tzong-Yi

“…Owing to the importance of the post-translational modifications (PTMs) of proteins in regulating biological processes, the dbPTM…”
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Bacterial communities in semen from men of infertile couples: metagenomic sequencing reveals relationships of seminal microbiota to semen quality by Weng, Shun-Long, Chiu, Chih-Min, Lin, Feng-Mao, Huang, Wei-Chih, Liang, Chao, Yang, Ting, Yang, Tzu-Ling, Liu, Chia-Yu, Wu, Wei-Yun, Chang, Yi-An, Chang, Tzu-Hao, Huang, Hsien-Da

“…Some previous studies have identified bacteria in semen as being a potential factor in male infertility. However, only few types of bacteria were taken into…”
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miRTarBase: a database curates experimentally validated microRNA-target interactions by Hsu, Sheng-Da, Lin, Feng-Mao, Wu, Wei-Yun, Liang, Chao, Huang, Wei-Chih, Chan, Wen-Ling, Tsai, Wen-Ting, Chen, Goun-Zhou, Lee, Chia-Jung, Chiu, Chih-Min, Chien, Chia-Hung, Wu, Ming-Chia, Huang, Chi-Ying, Tsou, Ann-Ping, Huang, Hsien-Da

“…MicroRNAs (miRNAs), i.e. small non-coding RNA molecules (~22 nt), can bind to one or more target sites on a gene transcript to negatively regulate protein…”
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MicroRNA‐483 amelioration of experimental pulmonary hypertension by Zhang, Jin, He, Yangyang, Yan, Xiaosong, Chen, Shanshan, He, Ming, Lei, Yuyang, Zhang, Jiao, Gongol, Brendan, Gu, Mingxia, Miao, Yifei, Bai, Liang, Cui, Xiaopei, Wang, Xiaojian, Zhang, Yixin, Fan, Fenling, Li, Zhao, Shen, Yuan, Chou, Chih‐Hung, Huang, Hsien‐Da, Malhotra, Atul, Rabinovitch, Marlene, Jing, Zhi‐Cheng, Shyy, John Y‐J

“…Endothelial dysfunction is critically involved in the pathogenesis of pulmonary arterial hypertension (PAH) and that exogenously administered microRNA may be…”
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STING as an emerging therapeutic target for drug discovery: Perspectives from the global patent landscape by Kong, Xiangjun, Zuo, Huali, Huang, Hsien-Da, Zhang, Qianru, Chen, Jiayu, He, Chengwei, Hu, Yuanjia

“…[Display omitted] •R&D efforts and outcomes targeting STING have been rapidly increasing, giving rise to a growing number of drug candidates in clinic and…”
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Krüppel-Like Factor 4 Regulation of Cholesterol-25-Hydroxylase and Liver X Receptor Mitigates Atherosclerosis Susceptibility by Li, Zhao, Martin, Marcy, Zhang, Jin, Huang, Hsi-Yuan, Bai, Liang, Zhang, Jiao, Kang, Jian, He, Ming, Li, Jie, Maurya, Mano R, Gupta, Shakti, Zhou, Guangjin, Sangwung, Panjamaporn, Xu, Yong-Jiang, Lei, Ting, Huang, Hsien-Da, Jain, Mohit, Jain, Mukesh K, Subramaniam, Shankar, Shyy, John Y.-J

“…BACKGROUND:Atherosclerosis is a multifaceted inflammatory disease involving cells in the vascular wall (eg, endothelial cells [ECs]), as well as circulating…”
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Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2 by Lin, Pei-Chin, Huang, Hsien-Da, Chang, Chun-Chi, Chang, Ya-Sian, Yen, Ju-Chen, Lee, Chien-Chih, Chang, Wen-Hsin, Liu, Ta-Chih, Chang, Jan-Gowth

“…Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis, and lncRNA taurine-upregulated gene 1 (TUG1) has been proven to be associated with several…”
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MicroRNA-92a Mediates Endothelial Dysfunction in CKD by Shang, Fenqing, Wang, Shen-Chih, Hsu, Chien-Yi, Miao, Yifei, Martin, Marcy, Yin, Yanjun, Wu, Chih-Cheng, Wang, Yun-Ting, Wu, Gaihong, Chien, Shu, Huang, Hsien-Da, Tarng, Der-Cherng, Shiu, Yan-Ting, Cheung, Alfred K, Huang, Po-Hsun, Chen, Zhen, Shyy, John Y-J

“…CKD is an independent risk factor for cardiovascular disease (CVD). The accumulation of uremic toxins in CKD induces oxidative stress and endothelial…”
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