Search Results - "Huang, Helen Q."

Randomized Trial of Intravenous Versus Intraperitoneal Chemotherapy Plus Bevacizumab in Advanced Ovarian Carcinoma: An NRG Oncology/Gynecologic Oncology Group Study by Walker, Joan L, Brady, Mark F, Wenzel, Lari, Fleming, Gini F, Huang, Helen Q, DiSilvestro, Paul A, Fujiwara, Keiichi, Alberts, David S, Zheng, Wenxin, Tewari, Krishnansu S, Cohn, David E, Powell, Matthew A, Van Le, Linda, Davidson, Susan A, Gray, Heidi J, Rose, Peter G, Aghajanian, Carol, Myers, Tashanna, Alvarez Secord, Angeles, Rubin, Stephen C, Mannel, Robert S

“…To evaluate the impact of two different intraperitoneal (IP) chemotherapy regimens on progression-free survival (PFS) among women with newly diagnosed advanced…”
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Quality of Life of Patients With Endometrial Cancer Undergoing Laparoscopic International Federation of Gynecology and Obstetrics Staging Compared With Laparotomy: A Gynecologic Oncology Group Study by KORNBLITH, Alice B, HUANG, Helen Q, WALKER, Joan L, SPIRTOS, Nick M, ROTMENSCH, Jacob, CELLA, David

“…The study's objective was to compare the quality of life (QoL) of patients with endometrial cancer undergoing surgical staging via laparoscopy versus…”
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GOG 244 - The Lymphedema and Gynecologic cancer (LeG) study: The impact of lower-extremity lymphedema on quality of life, psychological adjustment, physical disability, and function by Carter, Jeanne, Huang, Helen Q., Armer, Jane, Carlson, Jay W., Lockwood, Suzy, Nolte, Susan, Kauderer, James, Hutson, Alan, Walker, Joan L., Fleury, Aimee C., Bonebrake, Albert, Soper, John T., Mathews, Cara, Zivanovic, Oliver, Richards, William Edward, Tan, Annie, Alberts, David S., Barakat, Richard R., Wenzel, Lari B.

“…To assess quality of life (QOL) in patients who developed lower-extremity lymphedema (LLE) after radical gynecologic cancer surgery on prospective clinical…”
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Intraperitoneal Cisplatin and Paclitaxel in Ovarian Cancer by Armstrong, Deborah K, Bundy, Brian, Wenzel, Lari, Huang, Helen Q, Baergen, Rebecca, Lele, Shashikant, Copeland, Larry J, Walker, Joan L, Burger, Robert A

“…In a trial of adjuvant chemotherapy for ovarian cancer, a regimen of intravenous paclitaxel plus intraperitoneal cisplatin and paclitaxel was superior to…”
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Bevacizumab for advanced cervical cancer: patient-reported outcomes of a randomised, phase 3 trial (NRG Oncology–Gynecologic Oncology Group protocol 240) by Penson, Richard T, Prof, Huang, Helen Q, MS, Wenzel, Lari B, Prof, Monk, Bradley J, Prof, Stockman, Sharon, BA, Long, Harry J, Prof, Ramondetta, Lois M, MD, Landrum, Lisa M, PhD, Oaknin, Ana, MD, Reid, Thomas J A, MD, Leitao, Mario M, MD, Method, Michael, MD, Michael, Helen, Prof, Tewari, Krishnansu S, Prof

“…Summary Background GOG 240 was a practice-changing randomised phase 3 trial that concluded that chemotherapy plus bevacizumab for advanced cervical cancer…”
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Intraperitoneal catheter outcomes in a phase III trial of intravenous versus intraperitoneal chemotherapy in optimal stage III ovarian and primary peritoneal cancer: A Gynecologic Oncology Group Study by Walker, Joan L., Armstrong, Deborah K., Huang, Helen Q., Fowler, Jeffrey, Webster, Kenneth, Burger, Robert A., Clarke-Pearson, Daniel

“…To evaluate reasons for discontinuing intraperitoneal (IP) chemotherapy, and to compare characteristics of patients who did versus did not successfully…”
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Health-Related Quality of Life During and After Intraperitoneal Versus Intravenous Chemotherapy for Optimally Debulked Ovarian Cancer: A Gynecologic Oncology Group Study by WENZEL, Lari B, HUANG, Helen Q, ARMSTRONG, Deborah K, WALKER, Joan L, CELLA, David

“…A Gynecologic Oncology Group (GOG) randomized phase III trial (GOG 172) in optimal stage III epithelial ovarian cancer showed that intravenous (IV) paclitaxel…”
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Patient reported outcomes of a randomized, placebo-controlled trial of bevacizumab in the front-line treatment of ovarian cancer: A Gynecologic Oncology Group Study by Monk, Bradley J, Huang, Helen Q, Burger, Robert A, Mannel, Robert S, Homesley, Howard D, Fowler, Jeffrey, Greer, Benjamin E, Boente, Matthew, Liang, Sharon X, Wenzel, Lari

“…Abstract Purpose To analyze quality of life (QOL) in a randomized, placebo-controlled phase III trial concluding that the addition of concurrent and…”
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The association between quality of life domains and overall survival in ovarian cancer patients during adjuvant chemotherapy: A Gynecologic Oncology Group Study by von Gruenigen, Vivian E, Huang, Helen Q, Gil, Karen M, Frasure, Heidi E, Armstrong, Deborah K, Wenzel, Lari B

“…Abstract Purpose To explore the association between baseline quality of life (QOL) scores and overall survival (OS) in ovarian cancer patients receiving…”
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Quality of Life Outcomes From a Randomized Phase III Trial of Cisplatin With or Without Topotecan in Advanced Carcinoma of the Cervix: A Gynecologic Oncology Group Study by MONK, Bradley J, HUANG, Helen Q, CELLA, David, LONG, Harry J

“…To prospectively assess the impact of treatment with cisplatin alone or in combination with topotecan (CT) on quality of life (QOL) in patients with advanced…”
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Quality of life and survival in advanced cervical cancer: A Gynecologic Oncology Group study by Chase, Dana M, Huang, Helen Q, Wenzel, Lari, Cella, David, McQuellon, Richard, Long, Harry J, Moore, David H, Monk, Bradley J

“…Abstract Purpose To determine associations between pretreatment health-related quality of life subscales with progression-free (PFS) and overall survival (OS)…”
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Quality-of-Life Comparisons in a Randomized Trial of Interval Secondary Cytoreduction in Advanced Ovarian Carcinoma: A Gynecologic Oncology Group Study by WENZEL, Lari, HUANG, Helen Q, MONK, Bradley J, ROSE, Peter G, CELLA, David

“…To compare self-reported quality of life (QOL) in patients who did versus did not undergo interval secondary cytoreduction after initial surgery and…”
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Adjuvant Chemotherapy plus Radiation for Locally Advanced Endometrial Cancer by Matei, Daniela, Filiaci, Virginia, Randall, Marcus E, Mutch, David, Steinhoff, Margaret M, DiSilvestro, Paul A, Moxley, Katherine M, Kim, Yong M, Powell, Matthew A, O’Malley, David M, Spirtos, Nick M, Small, William, Tewari, Krishnansu S, Richards, William E, Nakayama, John, Matulonis, Ursula A, Huang, Helen Q, Miller, David S

“…After a median of nearly 4 years of follow-up, the use of radiotherapy combined with chemotherapy in patients with stage III or IVA endometrial carcinoma was…”
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A Comparison of Quality-of-Life Domains and Clinical Factors in Ovarian Cancer Patients: A Gynecologic Oncology Group Study by von Gruenigen, Vivian E., MD, Huang, Helen Q., MS, Gil, Karen M., PhD, Gibbons, Heidi E., MS, Monk, Bradley J., MD, Rose, Peter G., MD, Armstrong, Deborah K., MD, Cella, David, PhD, Wenzel, Lari, PhD

“…Abstract Context Women diagnosed with ovarian cancer are at risk for reduced quality of life (QOL). It is imperative to further define these declines to…”
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Secondary Surgical Cytoreduction for Recurrent Ovarian Cancer by Coleman, Robert L, Spirtos, Nick M, Enserro, Danielle, Herzog, Thomas J, Sabbatini, Paul, Armstrong, Deborah K, Kim, Jae-Weon, Park, Sang-Yoon, Kim, Byoung-Gie, Nam, Joo-Hyun, Fujiwara, Keiichi, Walker, Joan L, Casey, Ann C, Alvarez Secord, Angeles, Rubin, Steve, Chan, John K, DiSilvestro, Paul, Davidson, Susan A, Cohn, David E, Tewari, Krishnansu S, Basen-Engquist, Karen, Huang, Helen Q, Brady, Mark F, Mannel, Robert S

“…An NCI-sponsored, randomized clinical trial tested whether patients with relapsed ovarian cancer might benefit from surgical debulking of tumors followed by…”
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Trametinib versus standard of care in patients with recurrent low-grade serous ovarian cancer (GOG 281/LOGS): an international, randomised, open-label, multicentre, phase 2/3 trial by Gershenson, David M, Miller, Austin, Brady, William E, Paul, James, Carty, Karen, Rodgers, William, Millan, David, Coleman, Robert L, Moore, Kathleen N, Banerjee, Susana, Connolly, Kate, Secord, Angeles Alvarez, O'Malley, David M, Dorigo, Oliver, Gaillard, Stephanie, Gabra, Hani, Slomovitz, Brian, Hanjani, Parviz, Farley, John, Churchman, Michael, Ewing, Ailith, Hollis, Robert L, Herrington, C Simon, Huang, Helen Q, Wenzel, Lari, Gourley, Charlie

“…Low-grade serous carcinoma of the ovary or peritoneum is characterised by MAPK pathway aberrations and its reduced sensitivity to chemotherapy relative to…”
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Randomized Phase III Trial of Paclitaxel and Carboplatin Versus Paclitaxel and Ifosfamide in Patients With Carcinosarcoma of the Uterus or Ovary: An NRG Oncology Trial by Powell, Matthew A, Filiaci, Virginia L, Hensley, Martee L, Huang, Helen Q, Moore, Kathleen N, Tewari, Krishnansu S, Copeland, Larry J, Secord, Angeles A, Mutch, David G, Santin, Alessandro, Warshal, David P, Spirtos, Nick M, DiSilvestro, Paul A, Ioffe, Olga B, Miller, David S

“…This phase III randomized trial (NCT00954174) tested the null hypothesis that paclitaxel and carboplatin (PC) is inferior to paclitaxel and ifosfamide (PI) for…”
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GOG 244 - The LymphEdema and Gynecologic cancer (LEG) study: The association between the gynecologic cancer lymphedema questionnaire (GCLQ) and lymphedema of the lower extremity (LLE) by Carter, Jeanne, Huang, Helen Q., Armer, Jane, Carlson, Jay W., Lockwood, Suzy, Nolte, Susan, Stewart, Bob R., Kauderer, James, Hutson, Alan, Walker, Joan L., Fleury, Aimee C., Bonebrake, Albert, Soper, John T., Mathews, Cara, Zivanovic, Oliver, Richards, William Edwards, Tan, Annie, Alberts, David S., Barakat, Richard R., Wenzel, Lari

“…To explore whether patient-reported lymphedema-related symptoms, as measured by the Gynecologic Cancer Lymphedema Questionnaire (GCLQ), are associated with a…”
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An international randomized phase III trial of pulse actinomycin-D versus multi-day methotrexate for the treatment of low risk gestational trophoblastic neoplasia; NRG/GOG 275 by Schink, Julian C., Filiaci, Virginia, Huang, Helen Q., Tidy, John, Winter, Matthew, Carter, Jeanne, Anderson, Nancy, Moxley, Katherine, Yabuno, Akira, Taylor, Sarah E., Kushnir, Christina, Horowitz, Neil, Miller, David S.

“…Methotrexate and actinomycin-D are both effective first-line drugs for low-risk (WHO score 0–6) Gestational Trophoblastic Neoplasia (GTN) with considerable…”
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Chemotherapy completion in elderly women with ovarian, primary peritoneal or fallopian tube cancer – An NRG oncology/Gynecologic Oncology Group study by von Gruenigen, Vivian E, Huang, Helen Q, Beumer, Jan H, Lankes, Heather A, Tew, William, Herzog, Thomas, Hurria, Arti, Mannel, Robert S, Rizack, Tina, Landrum, Lisa M, Rose, Peter G, Salani, Ritu, Bradley, William H, Rutherford, Thomas J, Higgins, Robert V, Secord, Angeles Alvarez, Fleming, Gini

“…Abstract Purpose A simple measure to predict chemotherapy tolerance in elderly patients would be useful. We prospectively tested the association of baseline…”
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