Search Results - "Huang, Fengjuan"

Targeting ferroptosis as a prospective therapeutic approach for diabetic nephropathy by Wu, Qinrui, Huang, Fengjuan

“…Diabetic nephropathy (DN) is a severe complication of diabetes mellitus, causing a substantive threat to the public, which receives global concern. However,…”
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LncRNA H19: a novel player in the regulation of diabetic kidney disease by Wu, Qinrui, Huang, Fengjuan

“…Diabetic kidney disease (DKD), one of the most severe complications of diabetes mellitus (DM), has received considerable attention owing to its increasing…”
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FoxO1 Promotes Mitophagy in the Podocytes of Diabetic Male Mice via the PINK1/Parkin Pathway by Li, Wen, Du, Mengmeng, Wang, Qingzhu, Ma, Xiaojun, Wu, Lina, Guo, Feng, Ji, Hongfei, Huang, Fengjuan, Qin, Guijun

“…We recently showed that forkhead-box class O1 (FoxO1) activation protects against high glucose–induced injury by preventing mitochondrial dysfunction in the…”
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FoxO1-mediated inhibition of STAT1 alleviates tubulointerstitial fibrosis and tubule apoptosis in diabetic kidney disease by Huang, Fengjuan, Wang, Qingzhu, Guo, Feng, Zhao, Yanyan, Ji, Linlin, An, Tingting, Song, Yi, Liu, Yang, He, Yanyan, Qin, Guijun

“…Tubulointerstitial fibrosis (TIF) plays an important role in the progression of diabetic kidney disease (DKD). Forkhead box O1 (FoxO1) is involved in the…”
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Toll-like receptor-2 regulates macrophage polarization induced by excretory-secretory antigens from Schistosoma japonicum eggs and promotes liver pathology in murine schistosomiasis by Gong, Wenci, Huang, Fengjuan, Sun, Lei, Yu, Aiping, Zhang, Xiaofan, Xu, Yuxin, Shen, Yujuan, Cao, Jianping

“…Schistosomiasis is endemic to many regions of the world and affects approximately 200 million people. Conventional adaptive T cell responses are considered to…”
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Development and validation of a nomogram to estimate future risk of type 2 diabetes mellitus in adults with metabolic syndrome: prospective cohort study by Yang, Tongyue, Wang, Jiao, Wu, Lina, Guo, Feng, Huang, Fengjuan, Song, Yi, Jing, Na, Pan, Mengxing, Ding, Xiaoxu, Cao, Zhe, Liu, Shiyu, Qin, Guijun, Zhao, Yanyan

“…Objectives To develop and validate the 4-year risk of type 2 diabetes mellitus among adults with metabolic syndrome. Design Retrospective cohort study of a…”
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Dapagliflozin Attenuates Renal Tubulointerstitial Fibrosis Associated With Type 1 Diabetes by Regulating STAT1/TGFβ1 Signaling by Huang, Fengjuan, Zhao, Yanyan, Wang, Qingzhu, Hillebrands, Jan-Luuk, van den Born, Jacob, Ji, Linlin, An, Tingting, Qin, Guijun

“…Tubulointerstitial fibrosis (TIF) plays an important role in the progression of renal fibrosis in diabetic nephropathy (DN). Accumulating evidence supports a…”
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Associations between life’s essential 8 and metabolic health among us adults: insights of NHANES from 2005 to 2018 by Yang, Tongyue, Yi, Jiayi, Shao, Mingwei, Linlin, Zhao, Wang, Jiao, Huang, Fengjuan, Guo, Feng, Qin, Guijun, Zhao, Yanyan

“…Background Metabolic unhealth (MUH) is closely associated with cardiovascular disease (CVD). Life’s Essential 8 (LE8), a recently updated cardiovascular health…”
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Overexpression of FOXO1 ameliorates the podocyte epithelial–mesenchymal transition induced by high glucose in vitro and in vivo by Du, Mengmeng, Wang, Qingzhu, Li, Wen, Ma, Xiaojun, Wu, Lina, Guo, Feng, Zhao, Shuiying, Huang, Fengjuan, Wang, Huanhuan, Qin, Guijun

“…Accumulating evidence has suggested that the epithelial–mesenchymal transition (EMT) is a pathway that potentially leads to podocyte depletion and proteinuria…”
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The role of metabolic memory in diabetic kidney disease: identification of key genes and therapeutic targets by Yang, Tongyue, Feng, Qi, Shao, Mingwei, Pan, Mengxing, Guo, Feng, Song, Yi, Huang, Fengjuan, Linlin, Zhao, Wang, Jiao, Wu, Lina, Qin, Guijun, Zhao, Yanyan

“…Diabetic kidney disease (DKD) is characterized by complex pathogenesis and poor prognosis; therefore, an exploration of novel etiological factors may be…”
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Renal outcomes and prognostic factors in patients with type-2 diabetes and chronic kidney disease confirmed by renal biopsy by Jing, Na, Pan, Mengxing, Song, Yi, Guo, Feng, Zhang, Haohao, Wang, Jiao, Cao, Zhe, Liu, Shiyu, Wu, Lina, Ji, Hongfei, Huang, Fengjuan, Ding, Xiaoxu, Qi, Chang, Huang, Sen, Yang, Xinyu, Zhang, Li, Song, Chunhua, Qin, Guijun, Zhao, Yanyan

“…Aim: To evaluate the renal outcomes and prognostic factors among patients with type-2 diabetes (T2D) and biopsy-confirmed diabetic nephropathy (DN),…”
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Vitamin D3 supplementation improves testicular function in diabetic rats through peroxisome proliferator‐activated receptor‐γ/transforming growth factor‐beta 1/nuclear factor‐kappa B by Liu, Yang, He, Yanyan, Wang, Qingzhu, Guo, Feng, Huang, Fengjuan, Ji, Linlin, An, Tingting, Qin, Guijun

“…Aims/Introduction Vitamin D3 deficiency can lead to male hypogonadism in diabetes mellitus, but the target organs and the mechanism driving the disorder are…”
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Vitamin D3 Activates Phosphatidylinositol-3-Kinase/Protein Kinase B via Insulin-Like Growth Factor-1 to Improve Testicular Function in Diabetic Rats by Qin, Guijun, Ji, Linlin, Huang, Fengjuan, Guo, Feng, Wang, Qingzhu, Liu, Yang, He, Yanyan, An, Tingting

“…Objective. In diabetes mellitus, vitamin D3 deficiency affects sex hormone levels and male fertility; however, the mechanism leading to the disorder is…”
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Protective immunity against Schistosoma japonicum infection can be provided by IgG antibodies towards periodate-sensitive or periodate-resistant glycans by Gong, Wenci, Huang, Fengjuan, Ma, Yilei, Bai, Hongmei, Yin, Lan, Li, Jun, Chen, Chunxia, Xu, Xindong, Chen, Xiao-Ping

“…BACKGROUND: It has been well accepted that glycans present in schistosomes are highly antigenic. However, it is not clear what kind of worm glycans can affect…”
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Computational Investigation of Coaggregation and Cross-Seeding between Aβ and hIAPP Underpinning the Cross-Talk in Alzheimer’s Disease and Type 2 Diabetes by Fan, Xinjie, Zhang, Xiaohan, Yan, Jiajia, Xu, Huan, Zhao, Wenhui, Ding, Feng, Huang, Fengjuan, Sun, Yunxiang

“…The coexistence of amyloid-β (Aβ) and human islet amyloid polypeptide (hIAPP) in the brain and pancreas is associated with an increased risk of Alzheimer’s…”
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Dissecting the Self-assembly Dynamics of Imperfect Repeats in α‑Synuclein by Huang, Fengjuan, Wang, Ying, Zhang, Yu, Wang, Chuang, Lian, Jiangfang, Ding, Feng, Sun, Yunxiang

“…The pathological aggregation of α-synuclein (αS) into amyloid fibrils is the hallmark of Parkinson’s disease (PD). The self-assembly and membrane interactions…”
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Molecular Insights into the Effects of F16L and F19L Substitutions on the Conformation and Aggregation Dynamics of Human Calcitonin by Huang, Fengjuan, Huang, Jiahui, Yan, Jiajia, Liu, Yuying, Lian, Jiangfang, Sun, Qinxue, Ding, Feng, Sun, Yunxiang

“…Human calcitonin (hCT) regulates calcium–phosphorus metabolism, but its amyloid aggregation disrupts physiological activity, increases thyroid carcinoma risk,…”
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Unveiling Medin Folding and Dimerization Dynamics and Conformations via Atomistic Discrete Molecular Dynamics Simulations by Huang, Fengjuan, Fan, Xinjie, Wang, Ying, Wang, Chuang, Zou, Yu, Lian, Jiangfang, Ding, Feng, Sun, Yunxiang

“…Medin is a principal component of localized amyloid found in the vasculature of individuals over 50 years old. Its amyloid aggregation has been linked to…”
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Deciphering the influence of Y12L and N17H substitutions on the conformation and oligomerization of human calcitonin by Yan, Jiajia, Wang, Ying, Fan, Xinjie, Zou, Yu, Ding, Feng, Huang, Fengjuan, Sun, Yunxiang

“…The abnormal aggregation of human calcitonin (hCT) hormone peptides impairs their physiological function, leading to harmful immune responses and cytotoxicity,…”
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Molecular Insights into the Differential Effects of Acetylation on the Aggregation of Tau Microtubule-Binding Repeats by Zou, Yu, Guan, Lulu, Tan, Jingwang, Qi, Bote, Sun, Yunxiang, Huang, Fengjuan, Zhang, Qingwen

“…Aggregation of tau protein into intracellular fibrillary inclusions is characterized as the hallmark of tauopathies, including Alzheimer’s disease and chronic…”
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