Search Results - "Huang, C. D"

BH3-only proteins and their roles in programmed cell death by Giam, M, Huang, D C S, Bouillet, P

“…The Bcl-2 family of proteins controls the mitochondrial pathway to apoptosis. It consists of pro-survival and pro-apoptotic members, and their interactions…”
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A mobile telephone-based interactive self-care system improves asthma control by LIU, W.-T, HUANG, C.-D, WANG, C.-H, LEE, K.-Y, LIN, S.-M, KUO, H.-P

“…The self-management of asthma can improve clinical outcomes. Recently, mobile telephones have been widely used as an efficient, instant personal communication…”
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Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199 by Khaw, S L, Mérino, D, Anderson, M A, Glaser, S P, Bouillet, P, Roberts, A W, Huang, D C S

“…Overexpression of the prosurvival protein Bcl-2 marks many B-lymphoid malignancies and contributes to resistance to many commonly used chemotherapeutic agents…”
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Metal 3D-Printed 35–50-GHz Corrugated Horn for Cryogenic Operation by Gonzalez, A., Kaneko, K., Huang, C.-D., Huang, Y.-D.

“…All-metal 3D printing fabrication technologies provide an attractive alternative for direct manufacturing of waveguide components due to fast and…”
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Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1 by Teh, T-C, Nguyen, N-Y, Moujalled, D M, Segal, D, Pomilio, G, Rijal, S, Jabbour, A, Cummins, K, Lackovic, K, Blombery, P, Thompson, E, Ekert, P G, Lessene, G, Glaser, S P, Huang, D C S, Roberts, A W, Guthridge, M A, Wei, A H

“…Targeted therapies are frequently combined with standard cytotoxic drugs to enhance clinical response. Targeting the B-cell lymphoma 2 (BCL-2) family of…”
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Bone-filling mesh container versus percutaneous kyphoplasty in treating Kümmell’s disease by Duan, Z.-K., Zou, J.-F., He, X.-L., Huang, C.-D., He, C.-J.

“…Summary Kümmell’s disease (eponymous name for osteonecrosis and collapse of a vertebral body due to ischemia and non-union of anterior vertebral body wedge…”
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BET inhibition represses miR17-92 to drive BIM-initiated apoptosis of normal and transformed hematopoietic cells by Xu, Z, Sharp, P P, Yao, Y, Segal, D, Ang, C H, Khaw, S L, Aubrey, B J, Gong, J, Kelly, G L, Herold, M J, Strasser, A, Roberts, A W, Alexander, W S, Burns, C J, Huang, D C S, Glaser, S P

“…The BET ( b romodomain and e xtra t erminal domain) bromodomain-containing proteins, such as BRD4, are highly promising targets for treating lymphoid and…”
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Genetic effects of vascular endothelial growth factor and its receptor 2 on feather maturity in three chicken breeds by Tan, S.-W., Li, P.-Z., Li, H., Yu, H., Zhang, Z.-F, Zeng, Z., Huang, D.-C.

“…1. The goal of the current study was to evaluate the genetic effects of the vascular endothelial growth factor (VEGF) and its receptor (VEGFR-2) on feather…”
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HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death by Jacobsen, A V, Lowes, K N, Tanzer, M C, Lucet, I S, Hildebrand, J M, Petrie, E J, van Delft, M F, Liu, Z, Conos, S A, Zhang, J-G, Huang, D C S, Silke, J, Lessene, G, Murphy, J M

“…Necroptosis is a caspase-independent form of regulated cell death that has been implicated in the development of a range of inflammatory, autoimmune and…”
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ALMA Band 1 Optics (35–50 GHz): Tolerance Analysis, Effect of Cryostat Infrared Filters and Cold Beam Measurements by Gonzalez, A ., Tapia, V., Finger, R., Huang, C.-D., Asayama, S., Huang, Y.-D.

“…The Atacama Large Millimeter/Sub-millimeter Array (ALMA) is currently the largest (sub-)mm wave telescope in the world and will be used for astronomical…”
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The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia by Mason, K D, Khaw, S L, Rayeroux, K C, Chew, E, Lee, E F, Fairlie, W D, Grigg, A P, Seymour, J F, Szer, J, Huang, D C S, Roberts, A W

“…As chronic lymphocytic leukemia (CLL) is characterized by overexpression of pro-survival BCL2, compounds that mimic its physiological antagonists, the BH3-only…”
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Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML by DiNardo, C.D., Tiong, I.S., Quaglieri, A., MacRaild, S., Loghavi, S., Brown, F.C., Thijssen, R., Pomilio, G., Ivey, A., Salmon, J.M., Glytsou, C., Fleming, S.A., Zhang, Q., Ma, H., Patel, K.P., Kornblau, S.M., Xu, Z., Chua, C.C., Chen, Xufeng, Blombery, P., Flensburg, C., Cummings, N., Aifantis, I., Kantarjian, H., Huang, D.C.S, Roberts, A.W., Majewski, I.J., Konopleva, M., Wei, A.H.

“…The BCL-2 inhibitor venetoclax combined with hypomethylating agents or low-dose cytarabine represents an important new therapy for older or unfit patients with…”
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Bcl‐2 and Fas/APO‐1 regulate distinct pathways to lymphocyte apoptosis by Strasser, A., Harris, A. W., Huang, D. C., Krammer, P. H., Cory, S.

“…Activation of the cell surface receptor Fas/APO‐1 (CD95) induces apoptosis in lymphocytes and regulates immune responses. The cytoplasmic membrane protein…”
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Nucleic acid amplification test and bronchoscopy improve the diagnostic accuracy of smear-negative tuberculosis by Chou, P-C., Wang, C-H., Huang, C-D., Lo, Y-L., Lee, K-Y., Yu, C-T., Lin, S-M., Lin, H-C., Kuo, H-P.

“…OBJECTIVE: To determine whether the nucleic acid amplification (NAA) test on specimens collected by bronchoscopy improves the diagnostic accuracy of pulmonary…”
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The cell death inhibitor Bcl‐2 and its homologues influence control of cell cycle entry by O'Reilly, L. A., Huang, D. C., Strasser, A.

“…The effect of the cell death inhibitor Bcl‐2 and its homologues on cell cycle regulation was explored in lymphocytes and cell lines. Expression of a bcl‐2…”
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Quantitative design of seed load for solution cooling crystallization based on kinetic analysis by Huang, D.C., Liu, W., Zhao, S.K., Shi, Y.Q., Wang, Z.X., Sun, Y.M.

“…Seed load of crystallization has a direct effect on the product qualities. To further reveal the effects of seed load on crystallization kinetics and improve…”
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Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor by Lindqvist, L M, Vikström, I, Chambers, J M, McArthur, K, Ann Anderson, M, Henley, K J, Happo, L, Cluse, L, Johnstone, R W, Roberts, A W, Kile, B T, Croker, B A, Burns, C J, Rizzacasa, M A, Strasser, A, Huang, DC S

“…There is significant interest in treating cancers by blocking protein synthesis, to which hematological malignancies seem particularly sensitive. The…”
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Predictive factors for mortality among non-HIV-infected patients with pulmonary tuberculosis and respiratory failure by LIN, S-M, WANG, T-Y, LIU, W-T, CHANG, C-C, LIN, H-C, LIU, C-Y, WANG, C-H, HUANG, C-D, LEE, K-Y, KUO, H-P

“…OBJECTIVES: To determine predictive factors for mortality among pulmonary tuberculosis (PTB) patients without human immunodeficiency virus (HIV) infection and…”
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Virally mediated inhibition of Bax in leukocytes promotes dissemination of murine cytomegalovirus by Manzur, M, Fleming, P, Huang, D C S, Degli-Esposti, M A, Andoniou, C E

“…The evolutionary survival of viruses relies on their ability to disseminate infectious progeny to sites of transmission. The capacity to subvert apoptosis is…”
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Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands by Kvansakul, M, Yang, H, Fairlie, W D, Czabotar, P E, Fischer, S F, Perugini, M A, Huang, D C S, Colman, P M

“…Apoptosis is an important part of the host's defense mechanism for eliminating invading pathogens. Some viruses express proteins homologous in sequence and…”
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