Search Results - "Huang, Brian J"

Cell-based tissue engineering strategies used in the clinical repair of articular cartilage by Huang, Brian J, Hu, Jerry C, Athanasiou, Kyriacos A

“…Abstract One of the most important issues facing cartilage tissue engineering is the inability to move technologies into the clinic. Despite the multitude of…”
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Anti-Adhesion Behavior from Ring-Strain Amine Cyclic Monolayers Grafted on Silicon (111) Surfaces by Ching, Jing Yuan, Huang, Brian. J., Hsu, Yu-Ting, Khung, Yit Lung

“…In this manuscript, a series of amine tagged short cyclic molecules (cyclopropylamine, cyclobutylamine, cyclopentylamine and cyclohexylamine) were thermally…”
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Engineering large, anatomically shaped osteochondral constructs with robust interfacial shear properties by Brown, Wendy E., Huang, Brian J., Hu, Jerry C., Athanasiou, Kyriacos A.

“…Despite the prevalence of large (>5 cm 2 ) articular cartilage defects involving underlying bone, current tissue-engineered therapies only address small…”
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Bone regeneration with low dose BMP-2 amplified by biomimetic supramolecular nanofibers within collagen scaffolds by Lee, Sungsoo S, Huang, Brian J, Kaltz, Stuart R, Sur, Shantanu, Newcomb, Christina J, Stock, Stuart R, Shah, Ramille N, Stupp, Samuel I

“…Abstract Bone morphogenetic protein-2 (BMP-2) is a potent osteoinductive cytokine that plays a critical role during bone regeneration and repair. In the…”
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Effects of passage number and post-expansion aggregate culture on tissue engineered, self-assembled neocartilage by Huang, Brian J., Hu, Jerry C., Athanasiou, Kyriacos A.

“…[Display omitted] Chondrocyte dedifferentiation presents a major barrier in engineering functional cartilage constructs. To mitigate the effects of…”
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Engineering biomechanically functional neocartilage derived from expanded articular chondrocytes through the manipulation of cell‐seeding density and dexamethasone concentration by Huang, Brian J., Huey, Daniel J., Hu, Jerry C., Athanasiou, Kyriacos A.

“…Recent work has established methods to engineer self‐assembled, scaffold‐free neocartilage from an expanded articular chondrocyte (AC) cell source. In…”
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Tendon and ligament as novel cell sources for engineering the knee meniscus by Hadidi, Pasha, Paschos, Nikolaos K, Huang, Brian J, Aryaei, Ashkan, Hu, Jerry C, Athanasiou, Kyriacos A., Ph.D., P.E

“…Summary Objective The application of cell-based therapies in regenerative medicine is hindered by the difficulty of acquiring adequate numbers of competent…”
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Feasibility of in situ chondrogenesis for the entire umbilical cord in preliminary preparation for tracheal graft by Shai, Sen-Ei, Lai, Yi-Ling, Huang, Brian J, Yu, Kai-Jen, Hsieh, Chi-Wei, Chen, Yu-Shin, Hung, Shih-Chieh

“…There remains a scarcity of both autografts and allografts for tracheal transplantation after long-segmental resection. Subsequently, tissue engineering has…”
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Digoxin and adenosine triphosphate enhance the functional properties of tissue-engineered cartilage by Makris, Eleftherios A, Huang, Brian J, Hu, Jerry C, Chen-Izu, Ye, Athanasiou, Kyriacos A

“…Toward developing engineered cartilage for the treatment of cartilage defects, achieving relevant functional properties before implantation remains a…”
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De novo cartilage growth after implantation of a 3-D-printed tracheal graft in a porcine model by Shai, Sen-Ei, Lai, Yi-Ling, Hung, Yi-Wen, Hsieh, Chi-Wei, Huang, Brian J, Su, Kuo-Chih, Wang, Chun-Hsiang, Hung, Shih-Chieh

“…BACKGROUNDExperiments were conducted on the assumption that vivid chondrogenesis would be boosted in vivo following previously preliminary chondrogenesis in a…”
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Engineering biomechanically functional neocartilage derived from expanded articular chondrocytes through the manipulation of cell-seeding density and dexamethasone concentration: Engineering biomechanically functional cartilage by Huang, Brian J., Huey, Daniel J., Hu, Jerry C., Athanasiou, Kyriacos A.

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Scale-up of Engineered, Large, Anatomically Shaped Neocartilage with Robust Biomechanical Properties by Huang, Brian J

“…Osteoarthritis has been estimated to affect 13.5% of the adult U.S. population. Cartilage lesions range from small focal defects to large defects extending the…”
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