Search Results - "Hua-Xin Liao"

Antibody‐virus co‐evolution in HIV infection: paths for HIV vaccine development by Bonsignori, Mattia, Liao, Hua‐Xin, Gao, Feng, Williams, Wilton B., Alam, S. Munir, Montefiori, David C., Haynes, Barton F.

“…Summary Induction of HIV‐1 broadly neutralizing antibodies (bnAbs) to date has only been observed in the setting of HIV‐1 infection, and then only years after…”
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A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation by Kang, Sisi, Yang, Mei, He, Suhua, Wang, Yueming, Chen, Xiaoxue, Chen, Yao-Qing, Hong, Zhongsi, Liu, Jing, Jiang, Guanmin, Chen, Qiuyue, Zhou, Ziliang, Zhou, Zhechong, Huang, Zhaoxia, Huang, Xi, He, Huanhuan, Zheng, Weihong, Liao, Hua-Xin, Xiao, Fei, Shan, Hong, Chen, Shoudeng

“…Although human antibodies elicited by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein are profoundly boosted upon…”
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Tumor-associated antigen-based personalized dendritic cell vaccine in solid tumor patients by Wang, Qian-Ting, Nie, Ying, Sun, Sheng-Nan, Lin, Tao, Han, Ru-Jin, Jiang, Jun, Li, Zhe, Li, Jun-Qi, Xiao, Yun-Peng, Fan, Yu-Ying, Yuan, Xiao-Hui, Zhang, Hui, Zhao, Bin-Bin, Zeng, Ming, Li, Shi-You, Liao, Hua-Xin, Zhang, Jian, He, You-Wen

“…Tumor-associated antigens (TAAs) have been tested in various clinical trials in cancer treatment but the patterns of specific T cell response to personalized…”
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Genetic lineage tracing in skin reveals predominant expression of HEY2 in dermal papilla during telogen and that HEY2+ cells contribute to the regeneration of dermal cells during wound healing by Wang, Yan‐Ge, Yuan, Vicky Lan, Liao, Xin‐Hua

“…Dermal papilla (DP) cells are specialized mesenchymal cells that play a crucial role in regulating hair morphology, colour and growth through the secretion of…”
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Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG by Tomaras, Georgia D., Ferrari, Guido, Shen, Xiaoying, Alam, S. Munir, Liao, Hua-Xin, Pollara, Justin, Bonsignori, Mattia, Moody, M. Anthony, Fong, Youyi, Chen, Xi, Poling, Brigid, Nicholson, Cindo O., Zhang, Ruijun, Lu, Xiaozhi, Parks, Robert, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Gilbert, Peter B., Kim, Jerome H., Michael, Nelson L., Montefiori, David C., Haynes, Barton F.

“…Analysis of correlates of risk of infection in the RV144 HIV-1 vaccine efficacy trial demonstrated that plasma IgG against the HIV-1 envelope (Env) variable…”
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Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin by Whittle, James R. R, Zhang, Ruijun, Khurana, Surender, King, Lisa R, Manischewitz, Jody, Golding, Hana, Dormitzer, Philip R, Haynes, Barton F, Walter, Emmanuel B, Moody, M. Anthony, Kepler, Thomas B, Liao, Hua-Xin, Harrison, Stephen C

“…Seasonal antigenic drift of circulating influenza virus leads to a requirement for frequent changes in vaccine composition, because exposure or vaccination…”
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Expression dynamics of lymphoid enhancer‐binding factor 1 in terminal Schwann cells, dermal papilla, and interfollicular epidermis by Song, Hongzhi, Zhao, Xu‐Bo, Chu, Qing‐Song, Zhang, Jianyu, Gao, Lipeng, Liao, Xin‐Hua

“…Background Transcription factor lymphoid enhancer‐binding factor 1 (LEF1) is a downstream mediator of the Wnt/β‐catenin signaling pathway. It is expressed in…”
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Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth by Roskin, Krishna M., Jackson, Katherine J. L., Lee, Ji-Yeun, Hoh, Ramona A., Joshi, Shilpa A., Hwang, Kwan-Ki, Bonsignori, Mattia, Pedroza-Pacheco, Isabela, Liao, Hua-Xin, Moody, M. Anthony, Fire, Andrew Z., Borrow, Persephone, Haynes, Barton F., Boyd, Scott D.

“…A goal of HIV vaccine development is to elicit antibodies with neutralizing breadth. Broadly neutralizing antibodies (bNAbs) to HIV often have unusual…”
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Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies by Gao, Feng, Bonsignori, Mattia, Liao, Hua-Xin, Kumar, Amit, Xia, Shi-Mao, Lu, Xiaozhi, Cai, Fangping, Hwang, Kwan-Ki, Song, Hongshuo, Zhou, Tongqing, Lynch, Rebecca M., Alam, S. Munir, Moody, M. Anthony, Ferrari, Guido, Berrong, Mark, Kelsoe, Garnett, Shaw, George M., Hahn, Beatrice H., Montefiori, David C., Kamanga, Gift, Cohen, Myron S., Hraber, Peter, Kwong, Peter D., Korber, Bette T., Mascola, John R., Kepler, Thomas B., Haynes, Barton F.

“…Development of strategies for induction of HIV-1 broadly neutralizing antibodies (bnAbs) by vaccines is a priority. Determining the steps of bnAb induction in…”
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Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family by BONSIGNORI, Mattia, POLLARA, Justin, MARSHALL, Dawn J, WHITESIDES, John F, TSAO, Chun-Yen, KAEWKUNGWAL, Jaranit, NITAYAPHAN, Sorachai, PITISUTTITHUM, Punnee, RERKS-NGARM, Supachai, KIM, Jerome H, MICHAEL, Nelson L, TOMARAS, Georgia D, MOODY, M. Anthony, MONTEFIORI, David C, LEWIS, George K, DEVICO, Anthony, EVANS, David T, FERRARI, Guido, LIAO, Hua-Xin, HAYNES, Barton F, ALPERT, Michael D, XI CHEN, HWANG, Kwan-Ki, GILBERT, Peter B, YING HUANG, GURLEY, Thaddeus C, KOZINK, Daniel M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140 by Go, Eden P, Herschhorn, Alon, Gu, Christopher, Castillo-Menendez, Luis, Zhang, Shijian, Mao, Youdong, Chen, Haiyan, Ding, Haitao, Wakefield, John K, Hua, David, Liao, Hua-Xin, Kappes, John C, Sodroski, Joseph, Desaire, Heather

“…The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) trimer, which consists of the gp120 and gp41 subunits, is the focus of multiple…”
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Selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in HIV-1 broadly neutralizing antibodies by Henderson, Rory, Watts, Brian E., Ergin, Hieu N., Anasti, Kara, Parks, Robert, Xia, Shi-Mao, Trama, Ashley, Liao, Hua-Xin, Saunders, Kevin O., Bonsignori, Mattia, Wiehe, Kevin, Haynes, Barton F., Alam, S. Munir

“…Somatic mutations within antibody variable and framework regions (FWR) can alter thermostability and structural flexibility, but their impact on functional…”
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HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities by Pollara, Justin, Bonsignori, Mattia, Moody, M Anthony, Liu, Pinghuang, Alam, S Munir, Hwang, Kwan-Ki, Gurley, Thaddeus C, Kozink, Daniel M, Armand, Lawrence C, Marshall, Dawn J, Whitesides, John F, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Robb, Merlin L, O'Connell, Robert J, Kim, Jerome H, Michael, Nelson L, Montefiori, David C, Tomaras, Georgia D, Liao, Hua-Xin, Haynes, Barton F, Ferrari, Guido

“…The RV144 ALVAC/AIDSVax HIV-1 vaccine clinical trial showed an estimated vaccine efficacy of 31.2%. Viral genetic analysis identified a vaccine-induced site of…”
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A nomogram combining plasma fibrinogen and systemic immune‑inflammation index predicts survival in patients with resectable gastric cancer by Wang, Pan-Xing, Wang, Hai-Jiang, Liu, Jia-Huang, Qiu, Guang-Lin, Lu, Jing, Fan, Lin, Liao, Xin-Hua, Che, Xiang-Ming

“…Hyperfibrinogenemia and cancer-associated systemic inflammatory response are strongly associated with cancer progression and prognosis. We aimed to develop a…”
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Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody by Schmidt, Aaron G., Xu, Huafeng, Khan, Amir R., O'Donnell, Timothy, Khurana, Surender, King, Lisa R., Manischewitz, Jody, Golding, Hana, Suphaphiphat, Pirada, Carfi, Andrea, Settembre, Ethan C., Dormitzer, Philip R., Kepler, Thomas B., Zhang, Ruijun, Moody, M. Anthony, Haynes, Barton F., Liao, Hua-Xin, Shaw, David E., Harrison, Stephen C.

“…Affinity maturation refines a naive B-cell response by selecting mutations in antibody variable domains that enhance antigen binding. We describe a B-cell…”
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Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies by Yang, Guang, Holl, T Matt, Liu, Yang, Li, Yi, Lu, Xiaozhi, Nicely, Nathan I, Kepler, Thomas B, Alam, S Munir, Liao, Hua-Xin, Cain, Derek W, Spicer, Leonard, VandeBerg, John L, Haynes, Barton F, Kelsoe, Garnett

“…Many human monoclonal antibodies that neutralize multiple clades of HIV-1 are polyreactive and bind avidly to mammalian autoantigens. Indeed, the generation of…”
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Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses by Tay, Matthew Zirui, Liu, Pinghuang, Williams, LaTonya D, McRaven, Michael D, Sawant, Sheetal, Gurley, Thaddeus C, Xu, Thomas T, Dennison, S Moses, Liao, Hua-Xin, Chenine, Agnès-Laurence, Alam, S Munir, Moody, M Anthony, Hope, Thomas J, Haynes, Barton F, Tomaras, Georgia D

“…Emerging data support a role for antibody Fc-mediated antiviral activity in vaccine efficacy and in the control of HIV-1 replication by broadly neutralizing…”
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A novel controlled release formulation of the Pin1 inhibitor ATRA to improve liver cancer therapy by simultaneously blocking multiple cancer pathways by Yang, Dayun, Luo, Wensong, Wang, Jichuang, Zheng, Min, Liao, Xin-Hua, Zhang, Nan, Lu, Wenxian, Wang, Long, Chen, Ai-Zheng, Wu, Wen-Guo, Liu, Hekun, Wang, Shi-Bin, Zhou, Xiao Zhen, Lu, Kun Ping

“…Hepatocellular carcinoma (HCC) is the second leading cause of cancer deaths worldwide largely due to lack of effective targeted drugs to simultaneously block…”
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Role of HIV membrane in neutralization by two broadly neutralizing antibodies by Alam, S. Munir, Morelli, Marco, Dennison, S. Moses, Liao, Hua-Xin, Zhang, Ruijun, Xia, Shi-Mao, Rits-Volloch, Sophia, Sun, Li, Harrison, Stephen C, Haynes, Barton F, Chen, Bing

“…Induction of effective antibody responses against HIV-1 infection remains an elusive goal for vaccine development. Progress may require in-depth understanding…”
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Epidermal expression of Lgr6 is dependent on nerve endings and Schwann cells by Liao, Xin-Hua, Nguyen, Hoang

“…Lgr5/6 proteins are stem cell markers in various tissues. However, what determines their restricted expression pattern in these tissues remains unknown. We…”
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