Search Results - "Hua, Kuo‐Feng"
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Hepatoprotective Effect of Wheat-Based Solid-State Fermented Antrodia cinnamomea in Carbon Tetrachloride-Induced Liver Injury in Rat
Published in PloS one (05-04-2016)“…Antrodia cinnamomea (A. cinnamomea) is an indigenous medical fungus in Taiwan and has multiple biological functions, including hepatoprotective and…”
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Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy
Published in Journal of cellular physiology (01-07-2015)“…The NLRP3 inflammasome is a caspase‐1‐containing multi‐protein complex that controls the release of IL‐1β and plays important roles in the development of…”
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3
The Long Non-coding RNAs: Paramount Regulators of the NLRP3 Inflammasome
Published in Frontiers in immunology (25-09-2020)“…The NOD LRR pyrin domain containing protein 3 (NLRP3) inflammasome is a cytosolic multi-proteins conglomerate with intrinsic ATPase activity. Their predominant…”
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Editorial: Novel perspectives on the NLRP3 inflammasome
Published in Frontiers in immunology (12-05-2023)Get full text
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Ergosterol peroxide from marine fungus Phoma sp. induces ROS-dependent apoptosis and autophagy in human lung adenocarcinoma cells
Published in Scientific reports (18-12-2018)“…As part of our ongoing search for novel therapeutic structures from microorganism, the chemical examination of marine fungus Phoma sp . resulted in the…”
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IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis
Published in Journal of the American Society of Nephrology (01-07-2017)“…IL-36 cytokines are proinflammatory and have an important role in innate and adaptive immunity, but the role of IL-36 signaling in renal tubulointerstitial…”
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Mechanistic insight into the attenuation of gouty inflammation by Taiwanese green propolis via inhibition of the NLRP3 inflammasome
Published in Journal of cellular physiology (01-04-2019)“…Dysregulation of NACHT, LRR, and PYD domains‐containing protein 3 (NLRP3) inflammasome is involved in many chronic inflammatory diseases, including gouty…”
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Tris DBA ameliorates IgA nephropathy by blunting the activating signal of NLRP3 inflammasome through SIRT1‐ and SIRT3‐mediated autophagy induction
Published in Journal of cellular and molecular medicine (01-12-2020)“…Tris (dibenzylideneacetone) dipalladium (Tris DBA), a small‐molecule palladium complex, can inhibit cell growth and proliferation in pancreatic cancer,…”
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Corylin protects LPS-induced sepsis and attenuates LPS-induced inflammatory response
Published in Scientific reports (11-04-2017)“…Corylin is a main compound isolated from Psoralea corylifolia L. (Fabaceae). A variety of pharmacological effects such as antioxidant, anti-proliferation, and…”
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Pushing the Boundaries of Structural Heterogeneity with the Lipid A of Marine Bacteria Cellulophaga
Published in Chembiochem : a European journal of chemical biology (16-05-2023)“…Marine bacteria, which are often described as chemical gold, are considered an exceptional source of new therapeutics. Considerable research interest has been…”
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Accelerated, severe lupus nephritis benefits from treatment with honokiol by immunoregulation and differentially regulating NF‐κB/NLRP3 inflammasome and sirtuin 1/autophagy axis
Published in The FASEB journal (01-10-2020)“…Using honokiol (HNK), a major anti‐inflammatory bioactive compound in Magnolia officinalis, we show a potent therapeutic outcome against an accelerated, severe…”
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Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome
Published in Scientific reports (03-04-2019)“…The NLRP3 inflammasome promotes the pathogenesis of metabolic, neurodegenerative and infectious diseases. Increasing evidences show that the NLRP3 inflammasome…”
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A selective inhibitor of the NLRP3 inflammasome as a potential therapeutic approach for neuroprotection in a transgenic mouse model of Huntington's disease
Published in Journal of neuroinflammation (26-02-2022)“…Huntington's disease (HD) is a neurodegenerative disorder caused by the expansion of the CAG repeat in the huntingtin (HTT) gene. When the number of CAG…”
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A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP
Published in PloS one (27-07-2017)“…Antimicrobial peptides (AMPs) are one of the most important defense mechanisms against bacterial infections in insects, plants, non-mammalian vertebrates, and…”
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Activity Dependence of a Novel Lectin Family on Structure and Carbohydrate-Binding Properties
Published in Molecules (Basel, Switzerland) (30-12-2019)“…A GalNAc/Gal-specific lectins named CGL and MTL were isolated and characterized from the edible mussels and . Amino acid sequence analysis of these lectins…”
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Antibacterial and Antibiofilm Activities of Novel Antimicrobial Peptides against Multidrug-Resistant Enterotoxigenic Escherichia Coli
Published in International journal of molecular sciences (10-04-2021)“…Post-weaning diarrhea due to enterotoxigenic (ETEC) is a common disease of piglets and causes great economic loss for the swine industry. Over the past few…”
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Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells
Published in IUBMB life (01-12-2024)“…Lectins are carbohydrate‐binding proteins, whose biological effects are exerted via binding to glycoconjugates expressed on the surface of cells. Exposure to…”
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Cyclooxygenase-2 Regulates NLRP3 Inflammasome-Derived IL-1β Production
Published in Journal of cellular physiology (01-04-2015)“…The NLR family, pyrin domain‐containing 3 (NLRP3) inflammasome is a reactive oxygen species‐sensitive multiprotein complex that regulates IL‐1β maturation via…”
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Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation
Published in Arthritis research & therapy (19-11-2015)“…Lupus nephritis (LN) is a major complication of systemic lupus erythematosus. NLRP3 inflammasome activation, reactive oxygen species (ROS) and mononuclear…”
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Carboxylic and O-acetyl moieties are essential for the immunostimulatory activity of glucuronoxylomannan: a novel TLR4 specific immunostimulator from Auricularia auricula-judae
Published in Chemical communications (Cambridge, England) (2018)“…This study established the comprehensive repeating unit structure of immunologically active glucuronoxylomannan (AAPS) from wood ear mushroom, Auricularia…”
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