Search Results - "Hübel, Christopher"

Obesity remodels activity and transcriptional state of a lateral hypothalamic brake on feeding by Rossi, Mark A, Basiri, Marcus L, McHenry, Jenna A, Kosyk, Oksana, Otis, James M, van den Munkhof, Hanna E, Bryois, Julien, Hübel, Christopher, Breen, Gerome, Guo, Wilson, Bulik, Cynthia M, Sullivan, Patrick F, Stuber, Garret D

“…The current obesity epidemic is a major worldwide health concern. Despite the consensus that the brain regulates energy homeostasis, the neural adaptations…”
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Identifying typical trajectories in longitudinal data: modelling strategies and interpretations by Herle, Moritz, Micali, Nadia, Abdulkadir, Mohamed, Loos, Ruth, Bryant-Waugh, Rachel, Hübel, Christopher, Bulik, Cynthia M., De Stavola, Bianca L.

“…Individual-level longitudinal data on biological, behavioural, and social dimensions are becoming increasingly available. Typically, these data are analysed…”
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Genomics of body fat percentage may contribute to sex bias in anorexia nervosa by Hübel, Christopher, Gaspar, Héléna A., Coleman, Jonathan R. I., Finucane, Hilary, Purves, Kirstin L., Hanscombe, Ken B., Prokopenko, Inga, Graff, Mariaelisa, Ngwa, Julius S., Workalemahu, Tsegaselassie, O'Reilly, Paul F., Bulik, Cynthia M., Breen, Gerome

“…Anorexia nervosa (AN) occurs nine times more often in females than in males. Although environmental factors likely play a role, the reasons for this imbalanced…”
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Proteome-wide Mendelian randomization identifies causal links between blood proteins and severe COVID-19 by Palmos, Alish B, Millischer, Vincent, Menon, David K, Nicholson, Timothy R, Taams, Leonie S, Michael, Benedict, Sunderland, Geraint, Griffiths, Michael J, Hübel, Christopher, Breen, Gerome

“…In November 2021, the COVID-19 pandemic death toll surpassed five million individuals. We applied Mendelian randomization including >3,000 blood proteins as…”
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A longitudinal study of eating behaviours in childhood and later eating disorder behaviours and diagnoses by Herle, Moritz, Stavola, Bianca De, Hübel, Christopher, Abdulkadir, Mohamed, Ferreira, Diana Santos, Loos, Ruth J F, Bryant-Waugh, Rachel, Bulik, Cynthia M, Micali, Nadia

“…Eating behaviours in childhood are considered as risk factors for eating disorder behaviours and diagnoses in adolescence. However, few longitudinal studies…”
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Bidirectional relationship between eating disorders and autoimmune diseases by Hedman, Anna, Breithaupt, Lauren, Hübel, Christopher, Thornton, Laura M., Tillander, Annika, Norring, Claes, Birgegård, Andreas, Larsson, Henrik, Ludvigsson, Jonas F., Sävendahl, Lars, Almqvist, Catarina, Bulik, Cynthia M.

“…Background Immune system dysfunction may be associated with eating disorders (ED) and could have implications for detection, risk assessment, and treatment of…”
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Increased lipid and lipoprotein concentrations in anorexia nervosa: A systematic review and meta‐analysis by Hussain, Alia A., Hübel, Christopher, Hindborg, Mathias, Lindkvist, Emilie, Kastrup, Annie M., Yilmaz, Zeynep, Støving, René K., Bulik, Cynthia M., Sjögren, Jan M.

“…Objective Alterations in blood lipid concentrations in anorexia nervosa (AN) have been reported; however, the extent, mechanism, and normalization with weight…”
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The metabolic underpinning of eating disorders: A systematic review and meta-analysis of insulin sensitivity by Ilyas, Athif, Hübel, Christopher, Stahl, Daniel, Stadler, Marietta, Ismail, Khalida, Breen, Gerome, Treasure, Janet, Kan, Carol

“…A recent study reported a positive genetic correlation between anorexia nervosa and insulin sensitivity using data from genome-wide association studies…”
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Latent anxiety and depression dimensions differ amongst patients with eating disorders: A Swedish nationwide investigation by Hübel, Christopher, Birgegård, Andreas, Johansson, Therese, Petersen, Liselotte V, Isomaa, Rasmus, Herle, Moritz

“…Anxiety and depression symptoms are common in individuals with eating disorders. To study these co-occurrences, we need high-quality self-report…”
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The role of co-occurring conditions and genetics in the associations of eating disorders with attention-deficit/hyperactivity disorder and autism spectrum disorder by Christiansen, Gitte Bundgaard, Petersen, Liselotte Vogdrup, Chatwin, Hannah, Yilmaz, Zeynep, Schendel, Diana, Bulik, Cynthia M., Grove, Jakob, Brikell, Isabell, Semark, Birgitte Dige, Holde, Katrine, Abdulkadir, Mohamed, Hübel, Christopher, Albiñana, Clara, Vilhjálmsson, Bjarni Jóhann, Børglum, Anders D., Demontis, Ditte, Mortensen, Preben Bo, Larsen, Janne Tidselbak

“…Eating disorders (EDs) commonly co-occur with other psychiatric and neurodevelopmental disorders including attention-deficit/hyperactivity disorder (ADHD) and…”
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The Science Behind the Academy for Eating Disorders' Nine Truths About Eating Disorders by Schaumberg, Katherine, Welch, Elisabeth, Breithaupt, Lauren, Hübel, Christopher, Baker, Jessica H., Munn‐Chernoff, Melissa A., Yilmaz, Zeynep, Ehrlich, Stefan, Mustelin, Linda, Ghaderi, Ata, Hardaway, Andrew J., Bulik‐Sullivan, Emily C., Hedman, Anna M., Jangmo, Andreas, Nilsson, Ida A.K., Wiklund, Camilla, Yao, Shuyang, Seidel, Maria, Bulik, Cynthia M.

“…Objective In 2015, the Academy for Eating Disorders collaborated with international patient, advocacy, and parent organizations to craft the ‘Nine Truths About…”
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Eating behavior trajectories in the first 10 years of life and their relationship with BMI by Herle, Moritz, Stavola, Bianca De, Hübel, Christopher, Ferreira, Diana L. Santos, Abdulkadir, Mohamed, Yilmaz, Zeynep, Loos, Ruth J. F., Bryant-Waugh, Rachel, Bulik, Cynthia M., Micali, Nadia

“…Background Child eating behaviors are highly heterogeneous and their longitudinal impact on childhood weight is unclear. The objective of this study was to…”
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Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent by Hübel, Christopher, Gaspar, Héléna A., Coleman, Jonathan R. I., Hanscombe, Ken B., Purves, Kirstin, Prokopenko, Inga, Graff, Mariaelisa, Ngwa, Julius S., Workalemahu, Tsegaselassie, O’Reilly, Paul F., Bulik, Cynthia M., Breen, Gerome

“…Body composition is often altered in psychiatric disorders. Using genome-wide common genetic variation data, we calculate sex-specific genetic correlations…”
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Identifying research priorities for the study of atypical anorexia nervosa: A Delphi study by Strand, Mattias, Zvrskovec, Johan, Hübel, Christopher, Peat, Christine M, Bulik, Cynthia M, Birgegård, Andreas

“…Objective Individuals meeting all criteria for anorexia nervosa (AN) except that weight falls within or above the normal range despite significant weight loss…”
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Aberrant inflammatory profile in acute but not recovered anorexia nervosa by Nilsson, Ida A.K., Millischer, Vincent, Göteson, Andreas, Hübel, Christopher, Thornton, Laura M., Bulik, Cynthia M., Schalling, Martin, Landén, Mikael

“…Anorexia nervosa (AN) is a severe psychiatric disorder with high mortality and relapse rates. Even though changes in inflammatory markers and cytokines are…”
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Childhood overeating is associated with adverse cardiometabolic and inflammatory profiles in adolescence by Hübel, Christopher, Herle, Moritz, Santos Ferreira, Diana L., Abdulkadir, Mohamed, Bryant-Waugh, Rachel, Loos, Ruth J. F., Bulik, Cynthia M., Lawlor, Deborah A., Micali, Nadia

“…Childhood eating behaviour contributes to the rise of obesity and related noncommunicable disease worldwide. However, we lack a deep understanding of…”
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Persistent thinness and anorexia nervosa differ on a genomic level by Hübel, Christopher, Abdulkadir, Mohamed, Herle, Moritz, Palmos, Alish B, Loos, Ruth J F, Breen, Gerome, Micali, Nadia, Bulik, Cynthia M

“…Thinness and anorexia nervosa are both characterised by persistent low weight. Individuals with anorexia nervosa concurrently report distorted perceptions of…”
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The impact of anorexia nervosa and BMI polygenic risk on childhood growth: A 20-year longitudinal population-based study by Abdulkadir, Mohamed, Hübel, Christopher, Herle, Moritz, Loos, Ruth J F, Breen, Gerome, Bulik, Cynthia M, Micali, Nadia

“…Growth deviating from the norm during childhood has been associated with anorexia nervosa (AN) and obesity later in life. In this study, we examined whether…”
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Body composition in anorexia nervosa: Meta‐analysis and meta‐regression of cross‐sectional and longitudinal studies by Hübel, Christopher, Yilmaz, Zeynep, Schaumberg, Katherine E., Breithaupt, Lauren, Hunjan, Avina, Horne, Eleanor, García‐González, Judit, O'Reilly, Paul F., Bulik, Cynthia M., Breen, Gerome

“…Objective Clinically, anorexia nervosa (AN) presents with altered body composition. We quantified these alterations and evaluated their relationships with…”
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Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder by Mundy, Jessica, Hübel, Christopher, Adey, Brett N, Davies, Helena L, Davies, Molly R, Coleman, Jonathan R I, Hotopf, Matthew, Kalsi, Gursharan, Lee, Sang Hyuck, McIntosh, Andrew M, Rogers, Henry C, Eley, Thalia C, Murray, Robin M, Vassos, Evangelos, Breen, Gerome

“…The Mood Disorder Questionnaire (MDQ) is a common screening tool for bipolar disorder that assesses manic symptoms. Its utility for genetic studies of mania or…”
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