Search Results - "Hu, Yong‐Guo"
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A pH/Ultrasound dual-response biomimetic nanoplatform for nitric oxide gas-sonodynamic combined therapy and repeated ultrasound for relieving hypoxia
Published in Biomaterials (01-02-2020)“…Sonodynamic therapy (SDT) has rapidly developed as a powerful alternative to traditional photodynamic therapy due to its intrinsically deeper…”
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Red blood cell membrane-enveloped O2 self-supplementing biomimetic nanoparticles for tumor imaging-guided enhanced sonodynamic therapy
Published in Theranostics (01-01-2020)“…Non-invasive sonodynamic therapy (SDT) was developed because of its advantages of high penetration depth and low side effects; however, tumor hypoxia greatly…”
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Tumor Microenvironment‐Responsive Nanocarrier Based on VOx Nanozyme Amplify Oxidative Stress for Tumor Therapy
Published in Advanced functional materials (25-07-2023)“…The construction of a novel nanocarrier that can break the redox balance in tumor cell is a promising anti‐tumor strategy. Herein, a tumor microenvironment…”
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LncRNA MIAT Promotes Inflammation and Oxidative Stress in Sepsis-Induced Cardiac Injury by Targeting miR-330-5p/TRAF6/NF-κB Axis
Published in Biochemical genetics (01-10-2020)“…Sepsis is a whole-body inflammation and main cause of death in intensive care units worldwide. We aimed to investigate the roles of lncRNA MIAT and miR-330-5p…”
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A pH/ultrasonic dual-response step-targeting enterosoluble granule for combined sonodynamic-chemotherapy guided via gastrointestinal tract imaging in orthotopic colorectal cancer
Published in Nanoscale (25-02-2021)“…Colorectal cancer is one of the malignant tumors with high morbidity and lethality. Its efficient diagnosis and treatment has important significance. In this…”
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Spontaneous activity in medial orbitofrontal cortex correlates with trait anxiety in healthy male adults
Published in Journal of Zhejiang University. B. Science (01-08-2018)“…Medial orbitofrontal cortex (mOFC) abnormalities have been observed in various anxiety disorders. However, the relationship between mOFC activity and anxiety…”
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MFAP2 promotes epithelial-mesenchymal transition in gastric cancer cells by activating TGF-β/SMAD2/3 signaling pathway
Published in OncoTargets and therapy (01-01-2018)“…Microfibril-associated protein 2 (MFAP2) is an extracellular matrix protein that interacts with fibrillin to modulate the function of microfibrils. MFAP2 has…”
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ROS-augmented and tumor-microenvironment responsive biodegradable nanoplatform for enhancing chemo-sonodynamic therapy
Published in Biomaterials (01-03-2020)“…Nanocarrier for augmenting the efficacy of reactive oxygen species (ROS) by tumor microenvironment (TME) has become an emerging strategy for cancer treatment…”
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Rosmarinic Acid Attenuates Sodium Taurocholate-Induced Acute Pancreatitis in Rats by Inhibiting Nuclear Factor-κB Activation
Published in The American journal of Chinese medicine (1979) (2015)“…Rosmarinic Acid (RA), a caffeic acid ester, has been shown to exert anti-inflammation, anti-oxidant and antiallergic effects. Our study aimed to investigate…”
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Cyclopamine blocked the growth of colorectal cancer SW116 cells by modulating some target genes of Gli1 in vitro
Published in Hepato-gastroenterology (01-09-2011)“…Hedgehog (Hh) pathway has been considered as a therapy target for various cancer entities. However, its mechanism in colorectal cancer is still unclear. We…”
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Self-initiated nano-micelles mediated covalent modification of mRNA for labeling and treatment of tumors
Published in Angewandte Chemie International Edition (17-10-2024)“…As a promising gene therapy strategy, controllable small molecule-mRNA covalent modification in tumor cells could be initiated by singlet oxygen (1O2) to…”
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M1 macrophage-derived exosome for reprograming M2 macrophages and combining endogenous NO gas therapy with enhanced photodynamic synergistic therapy in colorectal cancer
Published in Journal of colloid and interface science (15-01-2024)“…[Display omitted] Reprogramming immunosuppressive M2 macrophages into M1 macrophages in tumor site provides a new strategy for the immunotherapy of colorectal…”
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A nanoplatform of hollow Ag2S/Ag nanocomposite shell for photothermal and enhanced sonodynamic therapy mediated by photoacoustic and CT imaging
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-04-2022)“…•A hollow Ag2S/Ag nanoshell composed of elemental Ag and compound Ag2S is synthesized.•The probe avoids the major defect of pure Ag shell gradual oxidiation…”
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Nanoplaform based on ultra-small Au regulating phototoxicity and fluorescence off–on function of Ag2S for multi-modal diagnosis and treatment of tumor
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-03-2022)“…•Hydrophobic ultra-small (3 ∼ 5 nm) nano-Au particle (mAu) is synthesized.•ASAuDP probe greatly reduces the phototoxicity of Ag2S.•Ag2S in ASAuDP probe…”
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Biomimetic O2 Self-generated hybrid membrane nanoplatform for blocking the polarization towards immunosuppressive M2 macrophage phenotype and enhancing sonodynamics therapy in orthotopic colorectal cancer
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-12-2022)Get full text
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Gelatinase-responsive biodegradable targeted microneedle patch for abscess wound treatment of S. aureus infection
Published in International journal of biological macromolecules (31-12-2023)“…Abscess wound caused by bacterial infection is usually difficult to heal, thus greatly affect people's quality of life. In this study, a biodegradable…”
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Free-Space Optical communication using visible light
Published in Journal of Zhejiang University. A. Science (01-02-2007)“…The possibility of visible red light laser being used as signal light source for Free-Space Optical (FSO) communication is proposed. Based on analysis of…”
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18
Separation of indium from iron in a rotating packed bed contactor using Di-2-ethylhexylphosphoric acid
Published in Separation and purification technology (30-05-2016)“…•IS–RPB as a novel reactor was employed for the separation of indium and iron.•The separation tests were carried out with In rich solution.•The separation…”
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Cascade-catalysed nanocarrier degradation for regulating metabolism homeostasis and enhancing drug penetration on breast cancer
Published in Journal of nanobiotechnology (06-11-2024)“…The abnormal structure of tumor vascular seriously hinders the delivery and deep penetration of drug in tumor therapy. Herein, an integrated and tumor…”
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Catalpol ameliorates sodium taurocholate-induced acute pancreatitis in rats via inhibiting activation of nuclear factor kappa B
Published in International journal of molecular sciences (04-07-2014)“…Catalpol, an iridoid glucoside extracted from the traditional Chinese herbal medicine, Rehmannia glutinosa, is reported to exert neuroprotective,…”
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