Search Results - "Hu, Yanhui"

An integrative approach to ortholog prediction for disease-focused and other functional studies by Hu, Yanhui, Flockhart, Ian, Vinayagam, Arunachalam, Bergwitz, Clemens, Berger, Bonnie, Perrimon, Norbert, Mohr, Stephanie E

“…Mapping of orthologous genes among species serves an important role in functional genomics by allowing researchers to develop hypotheses about gene function in…”
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Fast high-resolution miniature two-photon microscopy for brain imaging in freely behaving mice by Zong, Weijian, Wu, Runlong, Li, Mingli, Hu, Yanhui, Li, Yijun, Li, Jinghang, Rong, Hao, Wu, Haitao, Xu, Yangyang, Lu, Yang, Jia, Hongbo, Fan, Ming, Zhou, Zhuan, Zhang, Yunfeng, Wang, Aimin, Chen, Liangyi, Cheng, Heping

“…FHIRM-TPM is a miniature two-photon microscope capable of imaging fluorescently labeled neurons in the brains of freely behaving mice. It allows for imaging of…”
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Systemic Organ Wasting Induced by Localized Expression of the Secreted Insulin/IGF Antagonist ImpL2 by Kwon, Young, Song, Wei, Droujinine, Ilia A., Hu, Yanhui, Asara, John M., Perrimon, Norbert

“…Organ wasting, related to changes in nutrition and metabolic activity of cells and tissues, is observed under conditions of starvation and in the context…”
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Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets by Vinayagam, Arunachalam, Gibson, Travis E., Lee, Ho-Joon, Yilmazel, Bahar, Roesel, Charles, Hu, Yanhui, Kwon, Young, Sharma, Amitabh, Liu, Yang-Yu, Perrimon, Norbert, Barabási, Albert-László

“…The protein–protein interaction (PPI) network is crucial for cellular information processing and decision-making. With suitable inputs, PPI networks drive the…”
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Miniature two-photon microscopy for enlarged field-of-view, multi-plane and long-term brain imaging by Zong, Weijian, Wu, Runlong, Chen, Shiyuan, Wu, Junjie, Wang, Hanbin, Zhao, Zhe, Chen, Guoqing, Tu, Rui, Wu, Danlei, Hu, Yanhui, Xu, Yangyang, Wang, Yao, Duan, Zhuoli, Wu, Haitao, Zhang, Yunfeng, Zhang, Jue, Wang, Aimin, Chen, Liangyi, Cheng, Heping

“…We have developed a miniature two-photon microscope equipped with an axial scanning mechanism and a long-working-distance miniature objective to enable…”
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Coal Chemical Production Detection System Based on Fact Database by Yanhui Hu

“…In order to ensure the safety of coal chemical production, a dynamic model that conforms to actual production based on the fact database is established…”
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Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells by Viswanatha, Raghuvir, Li, Zhongchi, Hu, Yanhui, Perrimon, Norbert

“…Genome-wide screens in cells have offered numerous insights into gene function, yet a major limitation has been the inability to stably deliver large…”
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Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila by Cho, Bumsik, Yoon, Sang-Ho, Lee, Daewon, Koranteng, Ferdinand, Tattikota, Sudhir Gopal, Cha, Nuri, Shin, Mingyu, Do, Hobin, Hu, Yanhui, Oh, Sue Young, Lee, Daehan, Vipin Menon, A., Moon, Seok Jun, Perrimon, Norbert, Nam, Jin-Wu, Shim, Jiwon

“…The Drosophila lymph gland, the larval hematopoietic organ comprised of prohemocytes and mature hemocytes, has been a valuable model for understanding…”
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Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data by Hu, Yanhui, Vinayagam, Arunachalam, Nand, Ankita, Comjean, Aram, Chung, Verena, Hao, Tong, Mohr, Stephanie E, Perrimon, Norbert

“…Abstract Model organism and human databases are rich with information about genetic and physical interactions. These data can be used to interpret and guide…”
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Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase by Chen, Chiao-Lin, Hu, Yanhui, Udeshi, Namrata D, Lau, Thomas Y, Wirtz-Peitz, Frederik, He, Li, Ting, Alice Y, Carr, Steven A, Perrimon, Norbert

“…Characterization of the proteome of organelles and subcellular domains is essential for understanding cellular organization and identifying protein complexes…”
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Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9 by Ren, Xingjie, Sun, Jin, Housden, Benjamin E., Hu, Yanhui, Roesel, Charles, Lin, Shuailiang, Liu, Lu-Ping, Yang, Zhihao, Mao, Decai, Sun, Lingzhu, Wu, Qujie, Jie, Jun-Yuan, Xi, Jianzhong, Mohr, Stephanie E., Xu, Jiang, Perrimon, Norbert, Ni, Jian-Quan

“…The ability to engineer genomes in a specific, systematic, and cost-effective way is critical for functional genomic studies. Recent advances using the…”
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QNAR modeling of cytotoxicity of mixing nano-TiO2 and heavy metals by Yuan, Beilei, Wang, Pengfei, Sang, Leqi, Gong, Junhui, Pan, Yong, Hu, Yanhui

“…The Quantitative Structure-Activity Relationship (QSAR) has been used to investigate organic mixtures but QSAR in the nanomaterial field (QNAR) is still new…”
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The Transgenic RNAi Project at Harvard Medical School: Resources and Validation by Perkins, Lizabeth A, Holderbaum, Laura, Tao, Rong, Hu, Yanhui, Sopko, Richelle, McCall, Kim, Yang-Zhou, Donghui, Flockhart, Ian, Binari, Richard, Shim, Hye-Seok, Miller, Audrey, Housden, Amy, Foos, Marianna, Randkelv, Sakara, Kelley, Colleen, Namgyal, Pema, Villalta, Christians, Liu, Lu-Ping, Jiang, Xia, Huan-Huan, Qiao, Wang, Xia, Fujiyama, Asao, Toyoda, Atsushi, Ayers, Kathleen, Blum, Allison, Czech, Benjamin, Neumuller, Ralph, Yan, Dong, Cavallaro, Amanda, Hibbard, Karen, Hall, Don, Cooley, Lynn, Hannon, Gregory J, Lehmann, Ruth, Parks, Annette, Mohr, Stephanie E, Ueda, Ryu, Kondo, Shu, Ni, Jian-Quan, Perrimon, Norbert

“…To facilitate large-scale functional studies in Drosophila, the Drosophila Transgenic RNAi Project (TRiP) at Harvard Medical School (HMS) was established along…”
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CRISPR guide RNA design for research applications by Mohr, Stephanie E., Hu, Yanhui, Ewen‐Campen, Benjamin, Housden, Benjamin E., Viswanatha, Raghuvir, Perrimon, Norbert

“…The rapid rise of CRISPR as a technology for genome engineering and related research applications has created a need for algorithms and associated online tools…”
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Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control by Song, Wei, Cheng, Daojun, Hong, Shangyu, Sappe, Benoit, Hu, Yanhui, Wei, Neil, Zhu, Changqi, O’Connor, Michael B., Pissios, Pavlos, Perrimon, Norbert

“…While high-caloric diet impairs insulin response to cause hyperglycemia, whether and how counter-regulatory hormones are modulated by high-caloric diet is…”
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A single-cell survey of Drosophila blood by Tattikota, Sudhir Gopal, Cho, Bumsik, Liu, Yifang, Hu, Yanhui, Barrera, Victor, Steinbaugh, Michael J, Yoon, Sang-Ho, Comjean, Aram, Li, Fangge, Dervis, Franz, Hung, Ruei-Jiun, Nam, Jin-Wu, Ho Sui, Shannan, Shim, Jiwon, Perrimon, Norbert

“…blood cells, called hemocytes, are classified into plasmatocytes, crystal cells, and lamellocytes based on the expression of a few marker genes and cell…”
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Structured transverse orbital angular momentum probed by a levitated optomechanical sensor by Hu, Yanhui, Kingsley-Smith, Jack J., Nikkhou, Maryam, Sabin, James A., Rodríguez-Fortuño, Francisco J., Xu, Xiaohao, Millen, James

“…The momentum carried by structured light fields exhibits a rich array of surprising features. In this work, we generate transverse orbital angular momentum…”
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A gene-specific T2A-GAL4 library for Drosophila by Lee, Pei-Tseng, Zirin, Jonathan, Kanca, Oguz, Lin, Wen-Wen, Schulze, Karen L, Li-Kroeger, David, Tao, Rong, Devereaux, Colby, Hu, Yanhui, Chung, Verena, Fang, Ying, He, Yuchun, Pan, Hongling, Ge, Ming, Zuo, Zhongyuan, Housden, Benjamin E, Mohr, Stephanie E, Yamamoto, Shinya, Levis, Robert W, Spradling, Allan C, Perrimon, Norbert, Bellen, Hugo J

“…We generated a library of ~1000 stocks in which we inserted a construct in the intron of genes allowing expression of under control of endogenous promoters…”
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Enhanced Specificity and Efficiency of the CRISPR/Cas9 System with Optimized sgRNA Parameters in Drosophila by Ren, Xingjie, Yang, Zhihao, Xu, Jiang, Sun, Jin, Mao, Decai, Hu, Yanhui, Yang, Su-Juan, Qiao, Huan-Huan, Wang, Xia, Hu, Qun, Deng, Patricia, Liu, Lu-Ping, Ji, Jun-Yuan, Li, Jin Billy, Ni, Jian-Quan

“…The CRISPR/Cas9 system has recently emerged as a powerful tool for functional genomic studies in Drosophila melanogaster. However, single-guide RNA (sgRNA)…”
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Large-Scale Transgenic Drosophila Resource Collections for Loss- and Gain-of-Function Studies by Zirin, Jonathan, Hu, Yanhui, Liu, Luping, Yang-Zhou, Donghui, Colbeth, Ryan, Yan, Dong, Ewen-Campen, Ben, Tao, Rong, Vogt, Eric, VanNest, Sara, Cavers, Cooper, Villalta, Christians, Comjean, Aram, Sun, Jin, Wang, Xia, Jia, Yu, Zhu, Ruibao, Peng, Ping, Yu, Jinchao, Shen, Da, Qiu, Yuhao, Ayisi, Limmond, Ragoowansi, Henna, Fenton, Ethan, Efrem, Senait, Parks, Annette, Saito, Kuniaki, Kondo, Shu, Perkins, Liz, Mohr, Stephanie E, Ni, Jianquan, Perrimon, Norbert

“…Abstract The Transgenic RNAi Project (TRiP), a Drosophila melanogaster functional genomics platform at Harvard Medical School, was initiated in 2008 to…”
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