Search Results - "Hu, Xing‐Jie"

Nano Proteolysis Targeting Chimeras (PROTACs) with Anti‐Hook Effect for Tumor Therapy by Zhang, Ni‐Yuan, Hou, Da‐Yong, Hu, Xing‐Jie, Liang, Jian‐Xiao, Wang, Man‐Di, Song, Zhang‐Zhi, Yi, Li, Wang, Zhi‐Jia, An, Hong‐Wei, Xu, Wanhai, Wang, Hao

“…Proteolysis targeting chimera (PROTAC) is an emerging pharmacological modality with innovated post‐translational protein degradation capabilities. However,…”
Get full text

In Situ Constructed Nano‐Drug Depots through Intracellular Hydrolytic Condensation for Chemotherapy of Bladder Cancer by Hou, Da‐Yong, Zhang, Ni‐Yuan, Wang, Man‐Di, Xu, Shao‐Xin, Wang, Zhi‐Jia, Hu, Xing‐Jie, Lv, Gan‐Tian, Wang, Jia‐Qi, Wu, Xiu‐Hai, Wang, Lu, Cheng, Dong‐Bing, Wang, Hao, Xu, Wanhai

“…Intravesical administration of first‐line drugs has shown failure in the treatment of bladder cancer owing to the poor tumor retention time of…”
Get full text

An In Vivo Self‐Assembled Bispecific Nanoblocker for Enhancing Tumor Immunotherapy by Hu, Xing‐Jie, Zhang, Ni‐Yuan, Hou, Da‐Yong, Wang, Zhi‐Jia, Wang, Man‐Di, Yi, Li, Song, Zhang‐Zhi, Liang, Jian‐Xiao, Li, Xiang‐Peng, An, Hong‐Wei, Xu, Wanhai, Wang, Hao

“…Anti‐PD‐L1 monoclonal antibody has achieved substantial success in tumor immunotherapy by T‐cells activation. However, the excessive accumulation of…”
Get full text

In vivo assembly enhanced binding effect augments tumor specific ferroptosis therapy by Hou, Da-Yong, Cheng, Dong-Bing, Zhang, Ni-Yuan, Wang, Zhi-Jia, Hu, Xing-Jie, Li, Xin, Lv, Mei-Yu, Li, Xiang-Peng, Jian, Ling-Rui, Ma, Jin-Peng, Sun, Taolei, Qiao, Zeng-Ying, Xu, Wanhai, Wang, Hao

“…Emerging evidence indicates that the activation of ferroptosis by glutathione peroxidase 4 (GPX4) inhibitors may be a prominent therapeutic strategy for tumor…”
Get full text

An activated excretion-retarded tumor imaging strategy towards metabolic organs by Hou, Da-Yong, Wang, Man-Di, Hu, Xing-Jie, Wang, Zhi-Jia, Zhang, Ni-Yuan, Lv, Gan-Tian, Wang, Jia-Qi, Wu, Xiu-Hai, Wang, Lu, Wang, Hao, Xu, Wanhai

“…Intraoperative fluorescence-based tumor imaging plays a crucial role in performing the oncological safe tumor resection with the advantage of differentiating…”
Get full text

Programmable design and self assembly of peptide conjugated AIEgens for biomedical applications by Zhang, Ni-Yuan, Hu, Xing-Jie, An, Hong-Wei, Liang, Jian-Xiao, Wang, Hao

“…Aggregation-induced emission luminogens (AIEgens) possess enhanced fluorescence in highly aggregated states, thus enabling AIEgens as a promising module for…”
Get full text

Targeted in situ self-assembly augments peptide drug conjugate cell-entry efficiency by Wang, Man-Di, Hou, Da-Yong, Lv, Gan-Tian, Li, Ru-Xiang, Hu, Xing-Jie, Wang, Zhi-Jia, Zhang, Ni-Yuan, Yi, Li, Xu, Wan-Hai, Wang, Hao

“…Peptide drug conjugate (PDC) has emerged as one of the new generations of targeted therapeutics for cancer, which owns the advantages of improved drug…”
Get full text

A Lysosome-Targeting Self-Condensation Prodrug-Nanoplatform System for Addressing Drug Resistance of Cancer by Hou, Da-Yong, Wang, Man-Di, Zhang, Ni-Yuan, Xu, Shaoxin, Wang, Zhi-Jia, Hu, Xing-Jie, Lv, Gan-Tian, Wang, Jia-Qi, Lv, Mei-Yu, Yi, Li, Wang, Lu, Cheng, Dong-Bing, Sun, Taolei, Wang, Hao, Xu, Wanhai

“…Lysosome-targeting self-assembling prodrugs had emerged as an attractive approach to overcome the acquisition of resistance to chemotherapeutics by inhibiting…”
Get full text

A self-assembled fluorescent contrast agent targeting XIAP for image-guided surgery of bladder cancer by An, Hong-Wei, Hou, Da-Yong, Zhang, Ni-Yuan, Hu, Xing-Jie, Yi, Li, Liang, Jian-Xiao, Liu, Yi-Xuan, Zhang, Ying-Jin, Liao, Yu-Si, Xu, Wanhai, Wang, Hao

“…Fluorescently labeled tumor-specific molecular imaging agents have been extensively utilized in clinical settings to improve endoscopic tumor identification…”
Get full text

Endogenous formaldehyde responsive fluorescent probe for bioimaging by Yi, Ning-Bo, Hu, Xing-Jie, Wang, Fei, Chen, Si-Yi, Xu, Xiao-Xue, Li, Xin, Wang, Hao, Sun, Taolei, Qiao, Zeng-Ying, Cheng, Dong-Bing

“…Formaldehyde (FA), as the simplest endogenous carbonyl molecule, participates in many biosynthesis and metabolism in living organisms, such as nucleotides and…”
Get full text

A bispecific glycopeptide spatiotemporally regulates tumor microenvironment for inhibiting bladder cancer recurrence by An, Hong-Wei, Hou, Da-Yong, Yang, Jia, Wang, Zi-Qi, Wang, Man-Di, Zheng, Rui, Zhang, Ni-Yuan, Hu, Xing-Jie, Wang, Zhi-Jia, Wang, Lu, Liu, Di, Hao, Jun-Feng, Xu, Wanhai, Zhao, Yuliang, Wang, Hao

“…Up to 75% of bladder cancer patients suffer from recurrence due to postoperative tumor implantation. However, clinically used Bacillus Calmette-Guerin (BCG)…”
Get full text

Nano Proteolysis Targeting Chimeras (PROTACs) with Anti‐Hook Effect for Tumor Therapy by Zhang, Ni‐Yuan, Hou, Da‐Yong, Hu, Xing‐Jie, Liang, Jian‐Xiao, Wang, Man‐Di, Song, Zhang‐Zhi, Yi, Li, Wang, Zhi‐Jia, An, Hong‐Wei, Xu, Wanhai, Wang, Hao

“…Proteolysis targeting chimera (PROTAC) is an emerging pharmacological modality with innovated post‐translational protein degradation capabilities. However,…”
Get full text

In Situ Constructed Nano‐Drug Depots through Intracellular Hydrolytic Condensation for Chemotherapy of Bladder Cancer by Hou, Da‐Yong, Zhang, Ni‐Yuan, Wang, Man‐Di, Xu, Shao‐Xin, Wang, Zhi‐Jia, Hu, Xing‐Jie, Lv, Gan‐Tian, Wang, Jia‐Qi, Wu, Xiu‐Hai, Wang, Lu, Cheng, Dong‐Bing, Wang, Hao, Xu, Wanhai

“…Intravesical administration of first‐line drugs has shown failure in the treatment of bladder cancer owing to the poor tumor retention time of…”
Get full text

In vivo self-assembled bispecific fluorescence probe for early detection of bladder cancer and metastasis by Hou, Da-Yong, Zhang, Ni-Yuan, Zhang, Peng, Li, Xiang-Peng, Wu, Jiong-Cheng, Lv, Mei-Yu, Wang, Zhi-Jia, Hu, Xing-Jie, Liang, Jian-Xiao, Wang, Hong-Lei, Wang, Yue-Ze, You, Hui-Hui, An, Hong-Wei, Wang, Hao, Xu, Wanhai

“…Tumor metastasis accounts for over 90% of tumor-related deaths, prompting the development of fluorescently labeled tumor-specific molecular imaging agents for…”
Get full text

In Vivo Self-Assembled Bispecific Nano-Blocker for Enhancing Tumor Immunotherapy by Hu, Xing-Jie, Zhang, Ni-Yuan, Hou, Da-Yong, Wang, Zhi-Jia, Wang, Man-Di, Yi, Li, Song, Zhang-Zhi, Liang, Jian-Xiao, Li, Xiang-Peng, An, Hong-Wei, Xu, Wanhai, Wang, Hao

“…Anti-PD-L1 monoclonal antibody (mAb) has achieved substantial success in tumor immunotherapy by T-cells activation. However, owing to the excessive…”
Get full text

Puzzle and Challenge in Differentiating Immunoglobulin G4？related Cholangitis from Hilar Cholangiocarcinoma by Hu, Hai-Jie, Zhou, Rong-Xing, Shrestha, Anuj, Zhou, Yong, Li, Fu-Yu

“…Immunoglobulin G4 （IgG4）-related cholangitis （IAC） is one of the IgG4-related immune-mediated diseases. Although a study has provided a preliminary insight…”
Get full text

Carbon-free Cu2ZnSn（S,Se）4 film prepared via a non-hydrazine route by ZOU YuGang LIU Jie ZHANG Xing JIANG Yan HU JinSong WAN Li-Jun

“…The kesterite Cu2ZnSn（S,Se）4（CZTSSe） is an ideal candidate for light harvesting materials in earth-abundant low-cost thinfilm solar cells（TFSC）. Although the…”
Get full text

Six-step synthesis of Leonurine and toxicity study on zebrafish by Zhao, Hui, Hu, Xiang-Guo, Xu, Min-Jie, Cai, Qun-Xing, Liu, Yu-Jun, Su, Duo-Meng, Chen, Shi-Jin, Wang, Kai, Gong, Zhu-Nan

“…Leonurine（1）,an important ingredient in leonurus sibiricus L,can be used for some gynecological disease.We have developed a concise and efficient synthetic…”
Get full text

Bone marrow mesenchymal stem cell transplantation combined with perindopril treatment attenuates infarction remodelling in a rat model of acute myocardial infarction by Wang, Jian-an, Luo, Rong-hua, Zhang, Xing, Xie, Xiao-jie, Hu, Xin-yang, He, Ai-na, Chen, Jie, Li, Jia-hui

“…Objective： This study was performed to evaluate whether implantation of mesenchymal stem cell （MSC） would reduce left ventricular remodelling from the…”
Get full text

血清对细胞摄取DNA四面体纳米结构行为的影响 by 胡兴杰 王则君 殷敏 李迪 陈楠

“…研究了细胞培养基中的胎牛血清（FBS）对DNA四面体（Tetrahedral DNA nanostructure,TDNs）进入He…”
Get full text