Search Results - "Hu, Tianyuan"

Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis by Tu, Lichan, Su, Ping, Zhang, Zhongren, Gao, Linhui, Wang, Jiadian, Hu, Tianyuan, Zhou, Jiawei, Zhang, Yifeng, Zhao, Yujun, Liu, Yuan, Song, Yadi, Tong, Yuru, Lu, Yun, Yang, Jian, Xu, Cao, Jia, Meirong, Peters, Reuben J., Huang, Luqi, Gao, Wei

“…Triptolide is a trace natural product of Tripterygium wilfordii . It has antitumor activities, particularly against pancreatic cancer cells. Identification of…”
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De novo formation of a distinct coronary vascular population in neonatal heart by Tian, Xueying, Hu, Tianyuan, Zhang, Hui, He, Lingjuan, Huang, Xiuzhen, Liu, Qiaozhen, Yu, Wei, He, Liang, Yang, Zhen, Yan, Yan, Yang, Xiao, Zhong, Tao P., Pu, William T., Zhou, Bin

“…The postnatal coronary vessels have been viewed as developing through expansion of vessels formed during the fetal period. Using genetic lineage tracing, we…”
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Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions by Xu, Longyong, Liu, Xia, Peng, Fanglue, Zhang, Weijie, Zheng, Liting, Ding, Yao, Gu, Tianpeng, Lv, Kaosheng, Wang, Jin, Ortinau, Laura, Hu, Tianyuan, Shi, Xiangguo, Shi, Guojun, Shang, Ge, Sun, Shengyi, Iwawaki, Takao, Ji, Yewei, Li, Wei, Rosen, Jeffrey M., Zhang, Xiang H.-F., Park, Dongsu, Adoro, Stanley, Catic, Andre, Tong, Wei, Qi, Ling, Nakada, Daisuke, Chen, Xi

“…Stem cells need to be protected from genotoxic and proteotoxic stress to maintain a healthy pool throughout life 1 – 3 . Little is known about the proteostasis…”
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Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries by Tian, Xueying, Hu, Tianyuan, Zhang, Hui, He, Lingjuan, Huang, Xiuzhen, Liu, Qiaozhen, Yu, Wei, He, Liang, Yang, Zhongzhou, Zhang, Zhen, Zhong, Tao P, Yang, Xiao, Yang, Zhen, Yan, Yan, Baldini, Antonio, Sun, Yunfu, Lu, Jie, Schwartz, Robert J, Evans, Sylvia M, Gittenberger-de Groot, Adriana C, Red-Horse, Kristy, Zhou, Bin

“…Coronary arteries bring blood flow to the heart muscle. Understanding the developmental program of the coronary arteries provides insights into the treatment…”
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Identification and functional characterization of squalene epoxidases and oxidosqualene cyclases from Tripterygium wilfordii by Liu, Yuan, Zhou, Jiawei, Hu, Tianyuan, Lu, Yun, Gao, Linhui, Tu, Lichan, Gao, Jie, Huang, Luqi, Gao, Wei

“…Key message We cloned two squalene epoxidases and five oxidosqualene cyclases, and identified their function using CRISPR/Cas9 tool and yeast heterologous…”
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Detection of continuous hierarchical heterogeneity by single-cell surface antigen analysis in the prognosis evaluation of acute myeloid leukaemia by Shao, Nan, Ren, Chenshuo, Hu, Tianyuan, Wang, Dianbing, Zhu, Xiaofan, Li, Min, Cheng, Tao, Zhang, Yingchi, Zhang, Xian-En

“…Abstract Background Acute myeloid leukaemia (AML) is characterised by the malignant accumulation of myeloid progenitors with a high recurrence rate after…”
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ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response by Chapple, Richard H, Hu, Tianyuan, Tseng, Yu-Jung, Liu, Lu, Kitano, Ayumi, Luu, Victor, Hoegenauer, Kevin A, Iwawaki, Takao, Li, Qing, Nakada, Daisuke

“…Activation of the unfolded protein response (UPR) sustains protein homeostasis (proteostasis) and plays a fundamental role in tissue maintenance and longevity…”
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Yap1 Is Required for Endothelial to Mesenchymal Transition of the Atrioventricular Cushion by Zhang, Hui, von Gise, Alexander, Liu, Qiaozhen, Hu, Tianyuan, Tian, Xueying, He, Lingjuan, Pu, Wenjuan, Huang, Xiuzhen, He, Liang, Cai, Chen-Leng, Camargo, Fernando D., Pu, William T., Zhou, Bin

“…Cardiac malformations due to aberrant development of the atrioventricular (AV) valves are among the most common forms of congenital heart diseases. Normally,…”
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Transcriptome analysis reveals regulation mechanism of methyl jasmonate-induced terpenes biosynthesis in Curcuma wenyujin by Wei, Qiuhui, Lan, Kaer, Liu, Yuyang, Chen, Rong, Hu, Tianyuan, Zhao, Shujuan, Yin, Xiaopu, Xie, Tian

“…Curcuma wenyujin is the source plant of three traditional Chinese medicines, which have been widely used in clinical treatment over 1000 years. The content of…”
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An Investigation of the JAZ Family and the CwMYC2-like Protein to Reveal Their Regulation Roles in the MeJA-Induced Biosynthesis of β-Elemene in Curcuma wenyujin by Liu, Yuyang, Wu, Shiyi, Lan, Kaer, Wang, Qian, Ye, Tingyu, Jin, Huanan, Hu, Tianyuan, Xie, Tian, Wei, Qiuhui, Yin, Xiaopu

“…β-Elemene (C15H24), a sesquiterpenoid compound isolated from the volatile oil of Curcuma wenyujin, has been proven to be effective for multiple cancers and is…”
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Tandemly duplicated CYP82Ds catalyze 14-hydroxylation in triptolide biosynthesis and precursor production in Saccharomyces cerevisiae by Zhang, Yifeng, Gao, Jie, Ma, Lin, Tu, Lichan, Hu, Tianyuan, Wu, Xiaoyi, Su, Ping, Zhao, Yujun, Liu, Yuan, Li, Dan, Zhou, Jiawei, Yin, Yan, Tong, Yuru, Zhao, Huan, Lu, Yun, Wang, Jiadian, Gao, Wei, Huang, Luqi

“…Triptolide is a valuable multipotent antitumor diterpenoid in Tripterygium wilfordii , and its C-14 hydroxyl group is often selected for modification to…”
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Genetic targeting of sprouting angiogenesis using Apln-CreER by Liu, Qiaozhen, Hu, Tianyuan, He, Lingjuan, Huang, Xiuzhen, Tian, Xueying, Zhang, Hui, He, Liang, Pu, Wenjuan, Zhang, Libo, Sun, Heng, Fang, Jing, Yu, Ying, Duan, Shengzhong, Hu, Chaobo, Hui, Lijian, Zhang, Haibin, Quertermous, Thomas, Xu, Qingbo, Red-Horse, Kristy, Wythe, Joshua D., Zhou, Bin

“…Under pathophysiological conditions in adults, endothelial cells (ECs) sprout from pre-existing blood vessels to form new ones by a process termed…”
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Protein Engineering of a Germacrene A Synthase From Lactuca sativa and Its Application in High Productivity of Germacrene A in Escherichia coli by Chen, Rong, Liu, Yuheng, Chen, Shu, Wang, Ming, Zhu, Yao, Hu, Tianyuan, Wei, Qiuhui, Yin, Xiaopu, Xie, Tian

“…Germacrene A (GA) is a key intermediate for the synthesis of medicinal active compounds, especially for β-elemene, which is a broad-spectrum anticancer drug…”
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Transcriptional and Microenvironmental Regulation of Lineage Ambiguity in Leukemia by Hu, Tianyuan, Murdaugh, Rebecca, Nakada, Daisuke

“…Leukemia is characterized by the uncontrolled production of leukemic cells and impaired normal hematopoiesis. Although the combination of chemotherapies and…”
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Minimal residual disease monitoring in childhood Philadelphia chromosome-positive acute lymphoblastic leukemia: prognostic significance and correlation between multiparameter flow cytometry and real-time quantitative polymerase chain reaction by Li, Jun, Lu, Anni, Gao, Yangyang, Wan, Yang, Wang, Junxia, Zhang, Jingliao, Hu, Tianyuan, Wu, Peng, Chen, Xiaojuan, Zou, Yao, Chen, Yumei, Zhang, Li, Guo, Ye, Yang, Wenyu, Li, Chengwen, Zhang, Yingchi, Zhu, Xiaofan

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Selection and Identification of Novel Aptamers Specific for Clenbuterol Based on ssDNA Library Immobilized SELEX and Gold Nanoparticles Biosensor by Liu, Xixia, Lu, Qi, Chen, Sirui, Wang, Fang, Hou, Jianjun, Xu, Zhenlin, Meng, Chen, Hu, Tianyuan, Hou, Yaoyao

“…We describe a multiple combined strategy to discover novel aptamers specific for clenbuterol (CBL). An immobilized ssDNA library was used for the selection of…”
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The chromosome-level reference genome assembly for Panax notoginseng and insights into ginsenoside biosynthesis by Jiang, Zhouqian, Tu, Lichan, Yang, Weifei, Zhang, Yifeng, Hu, Tianyuan, Ma, Baowei, Lu, Yun, Cui, Xiuming, Gao, Jie, Wu, Xiaoyi, Tong, Yuru, Zhou, Jiawei, Song, Yadi, Liu, Yuan, Liu, Nan, Huang, Luqi, Gao, Wei

“…Panax notoginseng, a perennial herb of the genus Panax in the family Araliaceae, has played an important role in clinical treatment in China for thousands of…”
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Bmi1 Suppresses Adipogenesis in the Hematopoietic Stem Cell Niche by Hu, Tianyuan, Kitano, Ayumi, Luu, Victor, Dawson, Brian, Hoegenauer, Kevin A., Lee, Brendan H., Nakada, Daisuke

“…Bone marrow stromal cells (BMSCs) that express high levels of stem cell factor (SCF) and CXC chemokine ligand 12 (CXCL12) are one crucial component of the…”
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Overexpression of TwSQS, TwSE, and TwOSC Regulates Celastrol Accumulation in Cambial Meristematic Cells and Dedifferentiated Cells by Song, Yadi, Zhou, Jiawei, Zhang, Yifeng, Zhao, Yujun, Wang, Xiujuan, Hu, Tianyuan, Tong, Yuru, Huang, Luqi, Gao, Wei

“…Squalene synthase (SQS), squalene epoxidase (SE), and oxidosqualene cyclase (OSC) are encoding enzymes in downstream biosynthetic pathway of triterpenoid in…”
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A novel strategy to enhance terpenoids production using cambial meristematic cells of Tripterygium wilfordii Hook. f by Song, Yadi, Chen, Shang, Wang, Xiujuan, Zhang, Rui, Tu, Lichan, Hu, Tianyuan, Liu, Xihong, Zhang, Yifeng, Huang, Luqi, Gao, Wei

“…Hook. f. ( ) is an important medicinal plant with anti-inflammatory, immunosuppressive and anti-tumor activities. The main bioactive ingredients are…”
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