Search Results - "Hu, Tiannan"
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Simultaneous optimization of stiffener layout of 3D box structure together with attached tuned mass dampers under harmonic excitations
Published in Structural and multidisciplinary optimization (01-08-2021)“…This paper presents a novel and effective design method to improve the structural dynamic performance of 3D box structures subjected to harmonic excitations by…”
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2
Reaction–diffusion equation driven topology optimization of high-resolution and feature-rich structures using unstructured meshes
Published in Advances in engineering software (1992) (01-06-2023)“…Motivated by the need for porous structures in the design of biodegradable implants, as well as for the diverse and competitive designs in architecture, this…”
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TLR8 activation and inhibition by guanosine analogs in RNA: Importance of functional groups and chain length
Published in Bioorganic & medicinal chemistry (01-01-2018)“…[Display omitted] Toll-like receptor 8 (TLR8) is an important component of the human innate immune system that recognizes single stranded RNA (ssRNA). Recent…”
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4
Guide Strand 3′-End Modifications Regulate siRNA Specificity
Published in Chembiochem : a European journal of chemical biology (14-12-2016)“…Short interfering RNA (siRNA)‐triggered gene knockdown through the RNA interference (RNAi) pathway is widely used to study gene function, and siRNA‐based…”
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5
Stress-constrained topology optimization using the velocity field level set method
Published in Computers & structures (01-12-2024)“…•A stress-constrained topology optimization method using VFLS model is presented.•A new stress constraint in the single domain integral form is proposed.•The…”
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Improved adaptive growth method of stiffeners for three-dimensional box structures with respect to natural frequencies
Published in Computers & structures (15-10-2020)“…•An improved version of adaptive growth method is suggested.•Natural frequencies of box structures are improved with optimal stiffener layout.•The morphology…”
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7
Topology optimization of coated structures with layer-wise graded lattice infill for maximizing the fundamental eigenfrequency
Published in Computers & structures (15-10-2022)“…•Coated structures with layer-wise graded lattice microstructures optimized using the proposed method show higher fundamental eigenfrequency than those with…”
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Topology optimization for all-solid-state-batteries using homogenization method
Published in Structural and multidisciplinary optimization (01-09-2024)“…This paper proposes a Topology Optimization (TO) method for the design of microstructures within All-Solid-State Batteries (ASSBs), using the homogenization…”
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Topology optimization of embracing fixator considering bone remodeling to mitigate stress shielding effect
Published in Medical engineering & physics (01-03-2024)“…•Finite element based bone remodeling model is employed to simulate bone growth or resorption.•Time-dependent topology optimization algorithm is developed for…”
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10
Topology optimization of coated structures infilled with multiple materials
Published in Finite elements in analysis and design (01-08-2024)“…A novel topology optimization method for the design of coated structures infilled with multiple materials is proposed in this paper, where a novel material…”
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Multiscale topological design of coated structures with layer-wise bi-material lattice infill for minimum dynamic compliance
Published in Composite structures (01-11-2023)“…In this paper, a novel multiscale topological design strategy for coated structures infilled with layer-wise bi-material lattice microstructures is presented,…”
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Improving siRNA specificity with Guanosine Nucleobase Modifications: TLR8 Response and miRNA-like Off-Target Effect
Published 01-01-2019“…Since the discovery of RNA interference over 20 years ago, siRNA has emerged as a powerful tool in biological research. However, the clinical development of…”
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Dissertation -
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HYBRID OPTIMIZATION METHOD OF CONTINUUM STRUCTURE AND ITS SUPPORTING LOCATIONS
Published in Ji xie qiang du (01-01-2021)“…In engineering problems,there is interaction between the layout of supporting locations and the distribution of structural material. Thus,simultaneously…”
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