Search Results - "Hu, Sunli"

Stabilization of HIF-1α alleviates osteoarthritis via enhancing mitophagy by Hu, Sunli, Zhang, Chunwu, Ni, Libin, Huang, Chongan, Chen, Dingwen, Shi, Keqing, Jin, Haiming, Zhang, Kairui, Li, Yao, Xie, Ling, Fang, Mingqiao, Xiang, Guangheng, Wang, Xiangyang, Xiao, Jian

“…Mitochondrial dysfunction leads to osteoarthritis (OA) and disc degeneration. Hypoxia inducible factor-1α (HIF-1α) mediated mitophagy has a protective role in…”
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The therapeutic effect of TBK1 in intervertebral disc degeneration via coordinating selective autophagy and autophagic functions by Hu, Sunli, Chen, Liang, Al Mamun, Abdullah, Ni, Libin, Gao, Weiyang, Lin, Yan, Jin, Haiming, Zhang, Xiaolei, Wang, Xiangyang

“…[Display omitted] While its innate immune function has been known, recent works of literature have focused on the role of Tank binding kinase 1 (TBK1) in…”
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The homogeneous and heterogeneous risk factors for occurrence and prognosis in lung cancer patients with bone metastasis by Wang, Ben, Chen, Lijie, Huang, Chongan, Lin, Jialiang, Pan, Xiangxiang, Shao, Zhenxuan, Hu, Sunli, Zhang, Xiaolei, Wang, Xiangyang

“…•Survival time of lung cancer with BM observed was very lower than other foundings.•The only two homogeneous factors were male gender and metastasis to the…”
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Prognostic Determinants Analysis and Nomogram for Bone Malignant Vascular Tumors: A Surveillance, Epidemiology and End Results (SEER) Analysis by Hu, Sunli, Wang, Xiangyang

“…BACKGROUND The aim and objective of our investigations were to explore the prognostic value of various clinical and pathological factors of bone malignant…”
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Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages by Ni, Libin, Lin, Zhen, Hu, Sunli, Shi, Yifeng, Jiang, Zhichen, Zhao, Jiayi, Zhou, Yifei, Wu, Yaosen, Tian, Naifeng, Sun, Liaojun, Wu, Aimin, Pan, Zongyou, Zhang, Xiaolei, Wang, Xiangyang

“…[Display omitted] Osteoarthritis (OA) is a progressive joint disease characterized by the degradation and destruction of articular cartilage, which is involved…”
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Genistein protects intervertebral discs from degeneration via Nrf2‐mediated antioxidant defense system: An in vitro and in vivo study by Wang, Ke, Hu, Sunli, Wang, Ben, Wang, Jianle, Wang, Xiangyang, Xu, Cong

“…Oxidative stress has been reported to be closely associated with the development of intervertebral disc degeneration (IDD). IDD is one of the major causes of…”
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Promoting Nrf2/Sirt3-Dependent Mitophagy Suppresses Apoptosis in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration by Hu, Sunli, Zhang, Chenxi, Qian, Tianchen, Bai, Yue, Chen, Liang, Chen, Jiaoxiang, Huang, Chongan, Xie, Chenglong, Wang, Xiangyang, Jin, Haiming

“…One of the causes of intervertebral disc degeneration (IVDD) is nucleus pulposus cell (NPC) death, possibly apoptosis. In this study, we explored the role of…”
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BRD4 inhibition attenuates inflammatory response in microglia and facilitates recovery after spinal cord injury in rats by Wang, Jianle, Chen, Jiaoxiang, Jin, Haiming, Lin, Dongdong, Chen, Yu, Chen, Ximiao, Wang, Ben, Hu, Sunli, Wu, Yan, Wu, Yaosen, Zhou, Yifei, Tian, Naifeng, Gao, Weiyang, Wang, Xiangyang, Zhang, Xiaolei

“…The pathophysiology of spinal cord injury (SCI) involves primary injury and secondary injury. For the irreversibility of primary injury, therapies of SCI…”
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Dual regulation of microglia and neurons by Astragaloside IV‐mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury by Lin, Jialiang, Pan, Xiangxiang, Huang, Chongan, Gu, Mingbao, Chen, Ximiao, Zheng, Xuanqi, Shao, Zhenxuan, Hu, Sunli, Wang, Ben, Lin, Hao, Wu, Yaosen, Tian, Naifeng, Wu, Yan, Gao, Weiyang, Zhou, Yifei, Zhang, Xiaolei, Wang, Xiangyang

“…Inflammation and neuronal apoptosis contribute to the progression of secondary injury after spinal cord injury (SCI) and are targets for SCI therapy; autophagy…”
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Chemerin facilitates intervertebral disc degeneration via TLR4 and CMKLR1 and activation of NF-kB signaling pathway by Hu, Sunli, Shao, Zhenxuan, Zhang, Chenxi, Chen, Liang, Mamun, Abdullah Al, Zhao, Ning, Cai, Jinfeng, Lou, Zhiling, Wang, Xiangyang, Chen, Jiaoxiang

“…Now days, obesity is a major risk factor for intervertebral disc degeneration (IDD). However, adipokine, such as chemerin is a novel cytokine, which is…”
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RNA‐binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration by Shao, Zhenxuan, Ni, Libin, Hu, Sunli, Xu, Tianzhen, Meftah, Zaher, Yu, Zupo, Tian, Naifeng, Wu, Yaosen, Sun, Liaojun, Wu, Aimin, Pan, Zongyou, Chen, Linwei, Gao, Weiyang, Zhou, Yifei, Zhang, Xiaolei, Wang, Xiangyang

“…Objectives Diabetes is a risk factor for intervertebral disc degeneration (IVDD). Studies have demonstrated that diabetes may affect IVDD through…”
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Hydroxysafflor yellow A promotes multiterritory perforating flap survival: an experimental study by Zhang, Chenxi, Shao, Zhenxuan, Chen, Zhentai, Lin, Chen, Hu, Sunli, Lou, Zhiling, Li, Jiafeng, Zheng, Xuanqi, Lin, Nan, Gao, Weiyang

“…The use of perforator flaps is a common surgical technique in wound repair. However, the area surrounding the multiterritory perforating flap often becomes…”
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