Search Results - "Hu, Shunfeng"

Recent advances of ferroptosis in tumor: From biological function to clinical application by Hu, Shunfeng, Chu, Yurou, Zhou, Xiangxiang, Wang, Xin

“…Ferroptosis is a recently recognized form of cell death with distinct features in terms of morphology, biochemistry, and molecular mechanisms. Unlike other…”
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Eukaryotic initiation factor 3a promotes the development of diffuse large B-cell lymphoma through regulating cell proliferation by Sun, Hongkun, Shang, Juanjuan, Liu, Xiao, Ren, Shuai, Hu, Shunfeng, Wang, Xin

“…One-third of diffuse large B-cell lymphoma (DLBCL) patients suffer relapse after standard treatment. Eukaryotic initiation factor 3a (eIF3a) is a key player in…”
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Inhibition of Polo-like kinase 4 induces mitotic defects and DNA damage in diffuse large B-cell lymphoma by Zhao, Yi, Yang, Juan, Liu, Jiarui, Cai, Yiqing, Han, Yang, Hu, Shunfeng, Ren, Shuai, Zhou, Xiangxiang, Wang, Xin

“…Polo-like kinase 4 (PLK4), a key regulator of centriole biogenesis, has recently been shown to play key roles in tumorigenesis. Blocking PLK4 expression by…”
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Targeting natural killer cells: from basic biology to clinical application in hematologic malignancies by Shang, Juanjuan, Hu, Shunfeng, Wang, Xin

“…Natural killer (NK) cell belongs to innate lymphoid cell family that contributes to host immunosurveillance and defense without pre-immunization. Emerging…”
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The regulatory roles and clinical significance of glycolysis in tumor by Qiao, Qiqi, Hu, Shunfeng, Wang, Xin

“…Metabolic reprogramming has been demonstrated to have a significant impact on the biological behaviors of tumor cells, among which glycolysis is an important…”
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Advances and clinical applications of immune checkpoint inhibitors in hematological malignancies by Sun, Wenyue, Hu, Shunfeng, Wang, Xin

“…Immune checkpoints are differentially expressed on various immune cells to regulate immune responses in tumor microenvironment. Tumor cells can activate the…”
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Applications of single-cell technologies in drug discovery for tumor treatment by Liu, Bingyu, Hu, Shunfeng, Wang, Xin

“…Single-cell technologies have been known as advanced and powerful tools to study tumor biological systems at the single-cell resolution and are playing…”
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Ferroptosis-related STEAP3 acts as predictor and regulator in diffuse large B cell lymphoma through immune infiltration by Chen, Xiaomin, Hu, Shunfeng, Han, Yang, Cai, Yiqing, Lu, Tiange, Hu, Xinting, Chu, Yurou, Zhou, Xiangxiang, Wang, Xin

“…Diffuse large B cell lymphoma (DLBCL) is a usual-seen hematological malignant tumor possessing molecular and genetic heterogeneity. Ferroptosis induction has…”
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Single-cell transcriptome analysis profiles the expression features of TMEM173 in BM cells of high-risk B-cell acute lymphoblastic leukemia by Cai, Yiqing, Chen, Xiaomin, Lu, Tiange, Yu, Zhuoya, Hu, Shunfeng, Liu, Jiarui, Zhou, Xiangxiang, Wang, Xin

“…As an essential regulator of type I interferon (IFN) response, TMEM173 participates in immune regulation and cell death induction. In recent studies,…”
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N‐acetyltransferase 10 facilitates tumorigenesis of diffuse large B‐cell lymphoma by regulating AMPK/mTOR signalling through N4‐acetylcytidine modification of SLC30A9 by Ding, Mengfei, Yu, Zhuoya, Lu, Tiange, Hu, Shunfeng, Zhou, Xiangxiang, Wang, Xin

“…Background Accumulating studies suggested that posttranscriptional modifications exert a vital role in the tumorigenesis of diffuse large B‐cell lymphoma…”
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Derivation and validation of a lipid-covered prognostic model for mature T-cell lymphomas by Lu, Tiange, Shi, Lei, Shi, Guanggang, Cai, Yiqing, Hu, Shunfeng, Liu, Jiarui, Ren, Shuai, Zhou, Xiangxiang, Wang, Xin

“…Abstract Background Mature T-cell lymphomas (MTCLs), a group of diseases with high aggressiveness and vulnerable prognosis, lack for the accurate prognostic…”
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P1210: TARGETING PTGDS AS A NOVEL THERAPEUTIC APPROACH IN PERIPHERAL T CELL LYMPHOMA THROUGH REGULATING IRON METABOLISM by Hu, Shunfeng, Liu, Bingyu, Shang, Juanjuan, Lu, Tiange, Ding, Mengfei, Zhou, Xiangxiang, Wang, Xin

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N6-Methyladenosine RNA Methylation Regulators Contribute to Malignant Progression and Survival Prediction in Chronic Lymphocytic Leukemia by Zhang, Ya, Fang, Xiaosheng, Chen, Na, Lv, Xiao, Ge, Xueling, Lu, Kang, Zhou, Xiangxiang, Yang, Juan, Han, Yang, Hu, Shunfeng, Wang, Xin

“…Introduction N6-methyladenosine (m6A) RNA methylation is the most abundant epitranscriptomic modification, dynamically installed by the m6A methyltransferases…”
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PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations by Hu, Shunfeng, Lu, Tiange, Shang, Juanjuan, Cai, Yiqing, Ding, Mengfei, Zhou, Xiangxiang, Wang, Xin

“…Prostaglandin D2 (PGD2), an arachidonic acid metabolite, has been implicated in allergic responses, parasitic infection and tumor development. The biological…”
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Risk Stratification for Diffuse Large B-Cell Lymphoma by Integrating Interim Evaluation and International Prognostic Index: A Multicenter Retrospective Study by Shi, Xue, Liu, Xiaoqian, Li, Xiaomei, Li, Yahan, Lu, Dongyue, Sun, Xue, Li, Ying, Hu, Shunfeng, Zhang, Yuanfeng, Zhou, Xiangxiang, Wang, Xin, Chen, Haiping, Fang, Xiaosheng

“…The baseline International Prognostic Index (IPI) is not sufficient for the initial risk stratification of patients with diffuse large B-cell lymphoma (DLBCL)…”
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Circulating Exosomal MiR-107 Restrains Tumorigenesis in Diffuse Large B-Cell Lymphoma by Targeting 14-3-3η by Liu, Jiarui, Han, Yang, Hu, Shunfeng, Cai, Yiqing, Yang, Juan, Ren, Shuai, Zhao, Yi, Lu, Tiange, Zhou, Xiangxiang, Wang, Xin

“…Exosomes, nanometer-sized membranous vesicles in body fluids, have emerged as promising non-invasive biomarkers for cancer diagnosis. However, the function of…”
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Pegylated Liposomal Doxorubicin in Vindesine-Based and Bortezomib-Based Regimens for Patients With Newly Diagnosed Multiple Myeloma: A Retrospective Study of Efficacy and Safety by Zhai, Yujia, Yuan, Dai, Ge, Xueling, Hu, Shunfeng, Li, Peipei, Fang, Xiaosheng, Li, Ying, Zhou, Xiangxiang, Wang, Xin

“…Although pegylated liposomal doxorubicin (PLD) has been approved in combination with bortezomib for relapsed/refractory multiple myeloma (MM), the antitumor…”
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Derivation and validation of a nutrition-covered prognostic scoring system for extranodal NK/T-cell lymphoma by Lu, Tiange, Shi, Xue, Ge, Xueling, Li, Ying, Cai, Yiqing, Chen, Xiaomin, Hu, Shunfeng, Ding, Mei, Fang, Xiaosheng, Liu, Fang, Zhou, Xiangxiang, Wang, Xin

“…Patients with aggressive lymphomas are at high risk of losing body resources, resulting in malnutrition, immunodeficiency and inferior outcomes. Nutritional…”
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Update of antibody-drug conjugates for hematological malignancies by Sun, Wenyue, Hu, Shunfeng, Wang, Xin

“…Antibody-drug conjugates (ADCs), consisting of monoclonal antibodies (mAbs) covalently linked to cytotoxic drugs via chemical linkers, are a kind of promising…”
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Novel Risk Models and Promising Biomarkers for Prognostic Prediction in T-Cell Lymphoma with Pleural Effusion by Shang, Juanjuan, Hu, Shunfeng, Zhou, Xiaoli, Liu, Bingyu, Wang, Xin

“…Introduction: T-cell lymphomas (TCLs), a cluster of lymphoproliferative diseases, display high heterogeneity of characteristics, and lack for accurate…”
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