Search Results - "Hu, Shengshou"

Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function by Wang, Li, Yu, Peng, Zhou, Bingying, Song, Jiangping, Li, Zheng, Zhang, Mingzhi, Guo, Guangran, Wang, Yin, Chen, Xiao, Han, Leng, Hu, Shengshou

“…Owing to the prevalence and high mortality rates of cardiac diseases, a more detailed characterization of the human heart is necessary; however, this has been…”
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Resolving the intertwining of inflammation and fibrosis in human heart failure at single-cell level by Rao, Man, Wang, Xiliang, Guo, Guangran, Wang, Li, Chen, Shi, Yin, Pengbin, Chen, Kai, Chen, Liang, Zhang, Zemin, Chen, Xiao, Hu, Xueda, Hu, Shengshou, Song, Jiangping

“…Inflammation and fibrosis are intertwined mechanisms fundamentally involved in heart failure. Detailed deciphering gene expression perturbations and cell–cell…”
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Diagnostic Accuracy of Angiography-Based Quantitative Flow Ratio Measurements for Online Assessment of Coronary Stenosis by Xu, Bo, Tu, Shengxian, Qiao, Shubin, Qu, Xinkai, Chen, Yundai, Yang, Junqing, Guo, Lijun, Sun, Zhongwei, Li, Zehang, Tian, Feng, Fang, Weiyi, Chen, Jiyan, Li, Wei, Guan, Changdong, Holm, Niels R., Wijns, William, Hu, Shengshou

“…Quantitative flow ratio (QFR) is a novel angiography-based method for deriving fractional flow reserve (FFR) without pressure wire or induction of hyperemia…”
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Quality of primary health care in China: challenges and recommendations by Li, Xi, Krumholz, Harlan M, Yip, Winnie, Cheng, Kar Keung, De Maeseneer, Jan, Meng, Qingyue, Mossialos, Elias, Li, Chuang, Lu, Jiapeng, Su, Meng, Zhang, Qiuli, Xu, Dong Roman, Li, Liming, Normand, Sharon-Lise T, Peto, Richard, Li, Jing, Wang, Zengwu, Yan, Hongbing, Gao, Runlin, Chunharas, Somsak, Gao, Xin, Guerra, Raniero, Ji, Huijie, Ke, Yang, Pan, Zhigang, Wu, Xianping, Xiao, Shuiyuan, Xie, Xinying, Zhang, Yujuan, Zhu, Jun, Zhu, Shanzhu, Hu, Shengshou

“…China has substantially increased financial investment and introduced favourable policies for strengthening its primary health care system with core…”
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Off-Pump or On-Pump Coronary-Artery Bypass Grafting at 30 Days by Lamy, André, Devereaux, P.J, Prabhakaran, Dorairaj, Taggart, David P, Hu, Shengshou, Paolasso, Ernesto, Straka, Zbynek, Piegas, Leopoldo S, Akar, Ahmet Ruchan, Jain, Anil R, Noiseux, Nicolas, Padmanabhan, Chandrasekar, Bahamondes, Juan-Carlos, Novick, Richard J, Vaijyanath, Prashant, Reddy, Sukesh, Tao, Liang, Olavegogeascoechea, Pablo A, Airan, Balram, Sulling, Toomas-Andres, Whitlock, Richard P, Ou, Yongning, Ng, Jennifer, Chrolavicius, Susan, Yusuf, Salim

“…A total of 4752 patients for whom CABG was planned were randomly assigned to undergo the procedure on-pump or off-pump. At 30 days, the rates of death,…”
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Acute inflammation stimulates a regenerative response in the neonatal mouse heart by Han, Chunyong, Nie, Yu, Lian, Hong, Liu, Rui, He, Feng, Huang, Huihui, Hu, Shengshou

“…Cardiac injury in neonatal 1-day-old mice stimulates a regenerative response characterized by reactive cardio- myocyte proliferation, which is distinguished…”
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gp130 Controls Cardiomyocyte Proliferation and Heart Regeneration by Li, Yandong, Feng, Jie, Song, Shen, Li, Haotong, Yang, Huijun, Zhou, Bin, Li, Yan, Yue, Zhang, Lian, Hong, Liu, Lihui, Hu, Shengshou, Nie, Yu

“…A key cause of the high mortality of cardiovascular diseases is the cardiomyocyte inability to renew after cardiac injury. As a promising strategy to…”
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Summary of the 2022 Report on Cardiovascular Health and Diseases in China by Wang, Zengwu, Ma, Liyuan, Liu, Mingbo, Fan, Jing, Hu, Shengshou

“…Recent decades have seen the remarkable development of China in medical accessibility and quality index, and the application of a number of new advanced…”
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Transplantation of murine neonatal cardiac macrophage improves adult cardiac repair by Li, Yandong, Li, Haotong, Pei, Jianqiu, Hu, Shengshou, Nie, Yu

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A comparison of bilateral and unilateral cerebral perfusion for total arch replacement surgery for non-marfan, type A aortic dissection by Jiang, Qin, Huang, Keli, Wang, Deliang, Xia, Jiaqi, Yu, Tao, Hu, Shengshou

“…Objectives Acknowledging lacking of consensus exist in total aortic arch (TAA) surgery for acute type A aortic dissection (AAD), this study aimed to…”
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Five-Year Outcomes after Off-Pump or On-Pump Coronary-Artery Bypass Grafting by Lamy, André, Devereaux, P.J, Prabhakaran, Dorairaj, Taggart, David P, Hu, Shengshou, Straka, Zbynek, Piegas, Leopoldo S, Avezum, Alvaro, Akar, Ahmet R, Lanas Zanetti, Fernando, Jain, Anil R, Noiseux, Nicolas, Padmanabhan, Chandrasekar, Bahamondes, Juan-Carlos, Novick, Richard J, Tao, Liang, Olavegogeascoechea, Pablo A, Airan, Balram, Sulling, Toomas-Andres, Whitlock, Richard P, Ou, Yongning, Gao, Peggy, Pettit, Shirley, Yusuf, Salim

“…After 5 years of follow-up in this trial, the rates of the composite outcome of death, stroke, myocardial infarction, renal failure, or repeat…”
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Enhancing the precision of genetic lineage tracing using dual recombinases by He, Lingjuan, Li, Yan, Li, Yi, Pu, Wenjuan, Huang, Xiuzhen, Tian, Xueying, Wang, Yue, Zhang, Hui, Liu, Qiaozhen, Zhang, Libo, Zhao, Huan, Tang, Juan, Ji, Hongbin, Cai, Dongqing, Han, Zhibo, Han, Zhongchao, Nie, Yu, Hu, Shengshou, Wang, Qing-Dong, Sun, Ruilin, Fei, Jian, Wang, Fengchao, Chen, Ting, Yan, Yan, Huang, Hefeng, Pu, William T, Zhou, Bin

“…Genetic cell-lineage tracing studies in mice are crucial for delineating the contribution of stem and progenitor cells to different cell types, both in disease…”
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MicroRNA‐24 regulates cardiac fibrosis after myocardial infarction by Wang, Jue, Huang, Weicong, Xu, Ruixia, Nie, Yu, Cao, Xiaoqing, Meng, Jiang, Xu, Xiuqin, Hu, Shengshou, Zheng, Zhe

“…Cardiac fibrosis after myocardial infarction (MI) has been identified as a key factor in the development of heart failure. Although dysregulation of microRNA…”
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Preexisting endothelial cells mediate cardiac neovascularization after injury by He, Lingjuan, Huang, Xiuzhen, Kanisicak, Onur, Li, Yi, Wang, Yue, Li, Yan, Pu, Wenjuan, Liu, Qiaozhen, Zhang, Hui, Tian, Xueying, Zhao, Huan, Liu, Xiuxiu, Zhang, Shaohua, Nie, Yu, Hu, Shengshou, Miao, Xiang, Wang, Qing-Dong, Wang, Fengchao, Chen, Ting, Xu, Qingbo, Lui, Kathy O, Molkentin, Jeffery D, Zhou, Bin

“…The mechanisms that promote the generation of new coronary vasculature during cardiac homeostasis and after injury remain a fundamental and clinically…”
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CRISPR-CasRx knock-in mice for RNA degradation by Li, Jiacheng, Zhu, Dekun, Hu, Shengshou, Nie, Yu

“…The RNA editing tool CRISPR-CasRx has provided a platform for a range of transcriptome analysis tools and therapeutic approaches with its broad efficacy and…”
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Outline of the report on cardiovascular diseases in China, 2014 by Weiwei, Chen, Runlin, Gao, Lisheng, Liu, Manlu, Zhu, Wen, Wang, Yongjun, Wang, Zhaosu, Wu, Huijun, Li, Zhe, Zheng, Lixin, Jiang, Shengshou, Hu

“…The risk factors for cardiovascular diseases (CVDs) are more prevalent in the Chinese population, and therefore, increase the incidence of CVD. In general, CVD…”
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Direct reprogramming of fibroblasts into functional hepatocytes via CRISPRa activation of endogenous Gata4 and Foxa3 by Li, Jiacheng, Li, Ruopu, Bai, Xue, Zhang, Wenlong, Nie, Yu, Hu, Shengshou

“…The ability to generate functional hepatocytes without relying on donor liver organs holds significant therapeutic promise in the fields of regenerative…”
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Apoptosis of mesenchymal stem cells induced by hydrogen peroxide concerns both endoplasmic reticulum stress and mitochondrial death pathway through regulation of caspases, p38 and JNK by Wei, Hua, Li, Zongwei, Hu, Shengshou, Chen, Xi, Cong, Xiangfeng

“…Poor survival of mesenchymal stem cells (MSCs) compromised the efficacy of stem cell therapy for myocardial infarction. The increase of exogenous reactive…”
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Hypoxia and Serum Deprivation‐Induced Apoptosis in Mesenchymal Stem Cells by Zhu, Weiquan, Chen, Jinghai, Cong, Xiangfeng, Hu, Shengshou, Chen, Xi

“…In recent years, the understanding that regeneration progresses at the level of the myocardium has placed stem cell research at the center stage in cardiology…”
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Assessing Drug-Induced Mitochondrial Toxicity in Cardiomyocytes: Implications for Preclinical Cardiac Safety Evaluation by Tang, Xiaoli, Wang, Zengwu, Hu, Shengshou, Zhou, Bingying

“…Drug-induced cardiotoxicity not only leads to the attrition of drugs during development, but also contributes to the high morbidity and mortality rates of…”
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