Search Results - "Hu, Shengcao"
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Design, Synthesis and Anticancer Evaluation of Fangchinoline Derivatives
Published in Molecules (Basel, Switzerland) (08-11-2017)“…Twenty fangchinoline derivatives were synthesized from the natural product fangchinoline, and their anticancer activities on human breast cancer MDA-MB-231…”
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Fangchinoline derivatives induce cell cycle arrest and apoptosis in human leukemia cell lines via suppression of the PI3K/AKT and MAPK signaling pathway
Published in European journal of medicinal chemistry (15-01-2020)“…Fangchinoline, a bisbenzylisoquinoline alkaloid extracted from Stephania tetrandra S. Moore, is known to exert anti-cancer activity. A series of new…”
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Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors
Published in Journal of medicinal chemistry (11-08-2022)“…Covalent inhibitors with an electrophilic warhead have received considerable attention due to their remarkable pharmacological properties. However, the…”
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Design, synthesis, and evaluation of proliferation inhibitory activity of novel L-shaped ortho-quinone analogs as anticancer agents
Published in Bioorganic chemistry (01-12-2021)“…[Display omitted] •Novel L-shaped ortho-quinone analogs were designed and synthesized.•The cytotoxicities of most TD compounds were significant lower than…”
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Design and synthesis of novel C14-urea-tetrandrine derivatives with potent anti-cancer activity
Published in European journal of medicinal chemistry (01-01-2018)“…Tetrandrine is a dibenzyltetrahydroisoquinoline alkaloid, isolated from traditional Chinese medicinal plant Stephania tetrandra, with anti-tumor activity. Our…”
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Design, synthesis and bioactivity investigation of tetrandrine derivatives as potential anti-cancer agents
Published in MedChemComm (01-07-2018)“…Twenty-four 14-sulfonamide-tetrandrine derivatives as potential anti-cancer agents were synthesized. The synthetic derivatives were investigated for their…”
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Research on Flotation Process Test of Magnesite in Xinjiang
Published in Kuangchan Zonghe Liyong (01-04-2022)“…The multi-element and XRD diffraction analysis of a magnesite in Xinjiang shows that the main component of the ore is MgO, which exists in the form of…”
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Design, synthesis and bioactivity investigation of tetrandrine derivatives as potential anti-cancer agentsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8md00125a
Published 18-07-2018“…Twenty-four 14-sulfonamide-tetrandrine derivatives as potential anti-cancer agents were synthesized. The synthetic derivatives were investigated for their…”
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Design, synthesis and bioactivity investigation of tetrandrine derivatives as potential anti-cancer agents† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00125a
Published in MedChemComm (04-05-2018)“…Twenty-four 14-sulfonamide–tetrandrine derivatives were synthesized. Compound 23 exhibited growth inhibition of MDA-MB-231 cells with an IC 50 value of 1.18 ±…”
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新疆某菱镁矿浮选工艺实验研究
Published in 矿产综合利用 (01-04-2022)“…TD97; 对新疆某菱镁矿进行多元素及XRD衍射分析,该矿石主要成分为MgO,以碳酸镁的形式赋存与矿石中,脉石矿物主要以石英、白云石、方解石等为主的SiO2、CaO类杂质,该矿石属工业四级品.针对该矿性质,本实验采用预先脱泥-反-正浮选的工艺流程,在磨矿细度为-74 μm…”
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Design and synthesis of novel C 14 -urea-tetrandrine derivatives with potent anti-cancer activity
Published in European journal of medicinal chemistry (01-01-2018)“…Tetrandrine is a dibenzyltetrahydroisoquinoline alkaloid, isolated from traditional Chinese medicinal plant Stephania tetrandra, with anti-tumor activity. Our…”
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