Search Results - "Hu, Shaonan"

Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway by Hu, Shaonan, Wu, Yali, Zhao, Bo, Hu, Haiyan, Zhu, Baochen, Sun, Zongxi, Li, Pengyue, Du, Shouying

“…Oxidative stress plays a critical role in cerebral ischemia/reperfusion (I/R)-induced blood-brain barrier (BBB) disruption. saponins (PNS) possess efficient…”
Get full text

Ultrasound-induced cavitation renders prostate cancer cells susceptible to hyperthermia: Analysis of potential cellular and molecular mechanisms by Hu, Shaonan, Zhang, Xinrui, Melzer, Andreas, Landgraf, Lisa

“…Focused ultrasound (FUS) has become an important non-invasive therapy for prostate tumor ablation thermal effects in the clinic. The cavitation effect induced…”
Get full text

Causal inference of the effect of plasma proteins on the incidence of oral cancer: two-sample Mendelian randomization by Tian, Tao, Li, Simin, Hu, Shaonan, Zhao, Yiwei, Schmalz, Gerhard, Acharya, Aneesha, Huang, Shaohong

“…This study is aimed to investigate the causal relationship between plasma proteins and oral cancer risk using two-sample MR (Mendelian randomization)…”
Get full text

The genes regulating sensitivity of tumor cells to T cell-mediated killing: could they be potential personalized immunotherapeutic targets in head and neck squamous cell carcinoma? by Hu, Shaonan, Duan, Heng, Lu, Yongtao, Huang, Shaohong

“…Objective To identify the pivotal genes, specifically the STTK genes, that govern the sensitivity of tumor cells to T cell-mediated killing in Head and Neck…”
Get full text

Network pharmacology-based identification of protective mechanism of Panax Notoginseng Saponins on aspirin induced gastrointestinal injury by Zhu, Baochen, Zhang, Wantong, Lu, Yang, Hu, Shaonan, Gao, Rui, Sun, Zongxi, Chen, Xiaonan, Ma, Junming, Guo, Shuang, Du, Shouying, Li, Pengyue

“…[Display omitted] Aspirin is the first line therapy for cardiovascular and cerebrovascular diseases and is widely used. However aspirin-induced gastrointestinal…”
Get full text

Comparative Analysis of Compatibility Influence on Invigorating Blood Circulation for Combined Use of Panax Notoginseng Saponins and Aspirin Using Metabolomics Approach by Sun, Zongxi, Wu, Huichao, Wu, Yali, Wang, Chenglong, Wang, Yu, Hu, Shaonan, Du, Shouying

“…The combined use of Panax notoginseng saponins (PNS)-based drugs and aspirin (ASA) to combat vascular diseases has achieved good clinical results. In this…”
Get full text

Focused Ultrasound-Induced Cavitation Sensitizes Cancer Cells to Radiation Therapy and Hyperthermia by Hu, Shaonan, Zhang, Xinrui, Unger, Michael, Patties, Ina, Melzer, Andreas, Landgraf, Lisa

“…Focused ultrasound (FUS) has become an important non-invasive therapy for solid tumor ablation via thermal effects. The cavitation effect induced by FUS is…”
Get full text

Effects of Panax Notoginseng Saponins on Esterases Responsible for Aspirin Hydrolysis In Vitro by Sun, Zongxi, Wu, Yali, Liu, Song, Hu, Shaonan, Zhao, Bo, Li, Pengyue, Du, Shouying

“…Herb⁻drug interactions strongly challenge the clinical combined application of herbs and drugs. Herbal products consist of complex pharmacological-active…”
Get full text

Identifying crosstalk genetic biomarkers linking a neurodegenerative disease, Parkinson's disease, and periodontitis using integrated bioinformatics analyses by Hu, Shaonan, Li, Simin, Ning, Wanchen, Huang, Xiuhong, Liu, Xiangqiong, Deng, Yupei, Franceschi, Debora, Ogbuehi, Anthony Chukwunonso, Lethaus, Bernd, Savkovic, Vuk, Li, Hanluo, Gaus, Sebastian, Zimmerer, Rüdiger, Ziebolz, Dirk, Schmalz, Gerhard, Huang, Shaohong

“…To identify the genetic linkage mechanisms underlying Parkinson's disease (PD) and periodontitis, and explore the role of immunology in the crosstalk between…”
Get full text

Inhibitory Influence of Panax notoginseng Saponins on Aspirin Hydrolysis in Human Intestinal Caco-2 Cells by Sun, Zongxi, Wu, Yali, Yang, Bing, Zhu, Baochen, Hu, Shaonan, Lu, Yang, Zhao, Bo, Du, Shouying

“…Herb-drug interactions are important safety concerns in clinical practice. The interactions occur firstly in the intestinal absorption for orally administered…”
Get full text

Development of an on-column enrichment technique based on C₁₈-functionalized magnetic silica nanoparticles for the determination of lidocaine in rat plasma by high performance liquid chromatography by Chu, Bin, Lou, Dujuan, Yu, Panfeng, Hu, Shaonan, Shen, Shun

“…In this study, a novel on-column enrichment technique filled with C₁₈-functionalized magnetic silica nanoparticles was successfully developed for the…”
Get full text

Periodontal Inflamed Surface Area Is Associated With Increased Gestational Blood Pressure and Uric Acid Levels Among Pregnant Women From Rural North China by Hu, Shaonan, Yu, Feifan, Jiang, Hong, Shang, Wei, Miao, Hui, Li, Simin, Zhao, Jianjiang, Xiao, Hui

“…Periodontal disease has been associated with gestational complications and both conditions have a high prevalence in rural populations from developing regions…”
Get full text

Optimal time-point for neural stem cell transplantation to delay denervated skeletal muscle atrophy by Lin, Sen, Xu, Lei, Hu, Shaonan, Zhang, Changqing, Wang, Yang, Xu, Jianguang

“…Introduction: Transplantation of neural stem cells (NSCs) is a promising treatment to delay denervated skeletal muscle atrophy; however, the optimal time‐point…”
Get full text

Combined application of neutrophin-3 gene and neural stem cells is ameliorative to delay of denervated skeletal muscular atrophy after tibial nerve transection in rats by Lin, Sen, Xu, Jianguang, Hu, Shaonan, Xu, Lei, Zhang, Changqing, Wang, Yang, Gu, Yudong

“…Examination of the therapeutic efficacy of neural stem cells (NSCs) has recently become the focus of much investigation. In this study we present an insight of…”
Get full text

Panax notoginseng saponins suppress lipopolysaccharide‐induced barrier disruption and monocyte adhesion on bEnd.3 cells via the opposite modulation of Nrf2 antioxidant and NF‐κB inflammatory pathways by Hu, Shaonan, Liu, Tingting, Wu, Yali, Yang, Wanqing, Hu, Shaobo, Sun, Zongxi, Li, Pengyue, Du, Shouying

“…Dysfunction of the blood‐brain barrier (BBB) is a prerequisite for the pathogenesis of many cerebral diseases. Oxidative stress and inflammation are well‐known…”
Get full text

Novel Pheretima guillelmi-derived antithrombotic protein DPf3: Identification, characterization, in vitro evaluation and antithrombotic mechanisms investigation by Wu, Yali, Hu, Shaonan, Ma, Yunnan, Zhao, Bo, Yang, Wanqing, Lu, Yang, Li, Pengyue, Du, Shouying

“…In this study, the antithrombotic protein, named DPf3, was purified from Pheretima guillelmi by ion-exchange chromatography. The protein pattern of DPf3 was…”
Get full text

The Understanding of Vital Pulp Therapy in Permanent Teeth: A New Perspective by Shang, Wei, Zhang, Zeliang, Zhao, Xicong, Dong, Qingquan, Schmalz, Gerhard, Hu, Shaonan

“…The indications of vital pulp therapy (VPT) are expanding, which cases are suitable for VPT, and how to improve the success rate of VPT is a problem that often…”
Get full text

Transcriptomic-proteomics-anticoagulant bioactivity integrated study of Pheretima guillemi by Wu, Yali, Ma, Yunnan, Hu, Shaonan, Zhao, Bo, Yang, Wanqing, Sun, Zongxi, Zhu, Baochen, Lu, Yang, Li, Pengyue, Du, Shouying

“…Earthworms, a type of animal drugs from traditional Chinese medicine, have been used to treat coagulation for many years with less adverse effects and similar…”
Get full text

Ultrastructural analysis of peripheral-nerve regeneration within a nerve conduit by Li, Jifeng, Yan, Ji-Geng, Ai, Xun, Hu, Shaonan, Gu, Yu-Dong, Matloub, Hani S, Sanger, James R

“…The purpose of this study was to observe the cellular components of regenerating peripheral nerves within a nerve conduit. Rat sciatic nerves were placed in a…”
Get more information

Controllable Adaptive Molybdate‐Oligosaccharide Nanoparticles Regulate M2 Macrophage Mitochondrial Function and Promote Angiogenesis via PI3K/HIF‐1α/VEGF Pathway to Accelerate Diabetic Wound Healing by Huang, Xiuhong, Zheng, Liqin, Zhou, Yueshan, Hu, Shaonan, Ning, Wancheng, Li, Simin, Lin, Ziling, Huang, Shaohong

“…The complex wound environment of diabetic wounds leads to poor treatment efficacy, and the inflammatory disorders and vascular injury are the primary causes of…”
Get full text