Search Results - "Hu, Shannon J"
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The "Loss" of Perineuronal Nets in Alzheimer's Disease: Missing or Hiding in Plain Sight?
Published in Frontiers in integrative neuroscience (25-05-2022)“…Perineuronal nets (PNNs) are chondroitin-sulfate glycosaminoglycan (CS-GAG) containing extracellular matrix structures that assemble around neurons involved in…”
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Perineuronal net deglycosylation associates with tauopathy-induced gliosis and neurodegeneration
Published in Journal of neurochemistry (01-09-2024)“…Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by clinical symptoms of memory and cognitive deficiencies. Postmortem…”
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Diabetes exacerbates inflammatory bowel disease in mice with diet-induced obesity
Published in World journal of gastroenterology : WJG (07-09-2023)“…The increased prevalence of inflammatory bowel disease (IBD) among patients with obesity and type 2 diabetes suggests a causal link between these diseases,…”
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Decoding perineuronal net glycan sulfation patterns in the Alzheimer's disease brain
Published in Alzheimer's & dementia (01-05-2022)“…The extracellular matrix (ECM) of the brain comprises unique glycan “sulfation codes” that influence neurological function. Perineuronal nets (PNNs) are…”
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Neurogenin-3 Enteric Endocrinopathy: A Rare Case of Pediatric Congenital Diarrhea and Diabetes Mellitus
Published in JPGN reports (01-02-2022)“…Disorders of intestinal enteroendocrine cells (EEC) are a rare cause of congenital diarrhea and diabetes. The gene is essential in EEC differentiation, and…”
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157-OR: High-Fat–Diet Feeding Disrupts Thermal Responsiveness of AgRP Neurons
Published in Diabetes (New York, N.Y.) (01-06-2022)“…To defend energy homeostasis in the cold requires energy expenditure (to support thermogenesis) and energy intake increase, enabling core temperature to be…”
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1357-P: Diabetic Hyperglycemia Impairs Intestinal Barrier Function in the Setting of Diet-Induced Obesity
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Proper function of the intestinal barrier plays a crucial role to maintain normal health by selectively absorbing nutrients and keeping out pathogens…”
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Neurogenin-3 Enteric Endocrinopathy: A Rare Case of Pediatric Congenital Diarrhea and Diabetes Mellitus
Published in JPGN reports (01-02-2022)Get full text
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