Search Results - "Hu, Sanmei"

Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to Klebsiella pneumoniae and Ozone Exposure by Wang, Guirong, Umstead, Todd M, Hu, Sanmei, Mikerov, Anatoly N, Phelps, David S, Floros, Joanna

“…Surfactant protein A (SP-A) plays critical roles in host defense, regulation of inflammation and surfactant metabolism in the lung. The human SP-A locus…”
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Neutrophils and galectin-3 defend mice from lethal bacterial infection and humans from acute respiratory failure by Das, Sudipta, Kaminski, Tomasz W., Schlegel, Brent T., Bain, William, Hu, Sanmei, Patel, Akruti, Kale, Sagar L., Chen, Kong, Lee, Janet S., Mallampalli, Rama K., Kagan, Valerian E., Rajasundaram, Dhivyaa, McVerry, Bryan J., Sundd, Prithu, Kitsios, Georgios D., Ray, Anuradha, Ray, Prabir

“…Respiratory infection by Pseudomonas aeruginosa , common in hospitalized immunocompromised and immunocompetent ventilated patients, can be life-threatening…”
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GM-CSF overexpression after influenza a virus infection prevents mortality and moderates M1-like airway monocyte/macrophage polarization by Halstead, E Scott, Umstead, Todd M, Davies, Michael L, Kawasawa, Yuka Imamura, Silveyra, Patricia, Howyrlak, Judie, Yang, Linlin, Guo, Weichao, Hu, Sanmei, Hewage, Eranda Kurundu, Chroneos, Zissis C

“…Influenza A viruses cause life-threatening pneumonia and lung injury in the lower respiratory tract. Application of high GM-CSF levels prior to infection has…”
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Early life exposure to house dust mite allergen prevents experimental allergic asthma requiring mitochondrial H2O2 by Yuan, Huijuan, Chen, Jie, Hu, Sanmei, Oriss, Timothy B., Kale, Sagar Laxman, Das, Sudipta, Nouraie, Seyed M., Ray, Prabir, Ray, Anuradha

“…Immune tolerance to allergens in early-life decreases the risk for asthma in later life. Here we show establishment of stable airway tolerance to the allergen,…”
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SH3GLB2/endophilin B2 regulates lung homeostasis and recovery from severe influenza A virus infection by Fino, Kristin K., Yang, Linlin, Silveyra, Patricia, Hu, Sanmei, Umstead, Todd M., DiAngelo, Susan, Halstead, E. Scott, Cooper, Timothy K., Abraham, Thomas, Takahashi, Yoshinori, Zhou, Zhixiang, Wang, Hong Gang, Chroneos, Zissis C.

“…New influenza A viruses that emerge frequently elicit composite inflammatory responses to both infection and structural damage of alveolar-capillary barrier…”
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Interleukin-22 Inhibits Respiratory Syncytial Virus Production by Blocking Virus-Mediated Subversion of Cellular Autophagy by Das, Sudipta, St. Croix, Claudette, Good, Misty, Chen, Jie, Zhao, Jinming, Hu, Sanmei, Ross, Mark, Myerburg, Michael M., Pilewski, Joseph M., Williams, John, Wenzel, Sally E., Kolls, Jay K., Ray, Anuradha, Ray, Prabir

“…Respiratory syncytial virus (RSV) infection can cause severe bronchiolitis in infants requiring hospitalization, whereas the elderly and immunocompromised are…”
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SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation by Yang, Linlin, Carrillo, Marykate, Wu, Yuchieh M, DiAngelo, Susan L, Silveyra, Patricia, Umstead, Todd M, Halstead, E Scott, Davies, Michael L, Hu, Sanmei, Floros, Joanna, McCormack, Francis X, Christensen, Neil D, Chroneos, Zissis C

“…The surfactant protein (SP-A) receptor SP-R210 has been shown to increase phagocytosis of SP-A-bound pathogens and to modulate cytokine secretion by immune…”
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Impact of Ozone, Sex, and Gonadal Hormones on Bronchoalveolar Lavage Characteristics and Survival in SP-A KO Mice Infected with Klebsiella pneumoniae by Gandhi, Chintan K., Mikerov, Anatoly N., Durrani, Faryal, Umstead, Todd M., Hu, Sanmei, Wang, Guirong, Phelps, David S., Floros, Joanna

“…Surfactant protein A (SP-A) plays an important role in innate immunity. The sex-dependent survival of infected SP-A knockout (KO) mice has been observed. Our…”
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Peripheral osmotic stimulation inhibits the brain's innate immune response to microdialysis of acidic perfusion fluid adjacent to supraoptic nucleus by Summy-Long, Joan Y, Hu, Sanmei

“…During the brain's innate immune response microglia, astroglia and ependymal cells resolve/repair damaged tissue and control infection. Released…”
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Dual role for CXCR3 and CCR5 in asthmatic type 1 inflammation by Gauthier, Marc, Kale, Sagar Laxman, Oriss, Timothy B., Scholl, Kathryn, Das, Sudipta, Yuan, Huijuan, Hu, Sanmei, Chen, Jie, Camiolo, Matthew, Ray, Prabir, Wenzel, Sally, Ray, Anuradha

“…Many patients with severe asthma (SA) fail to respond to type 2 inflammation–targeted therapies. We previously identified a cohort of subjects with SA…”
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Establishment of airway tolerance in early life to inhaled house dust mite involves mitochondrial H2O2 by Yuan, Huijuan, Chen, Jie, Hu, Sanmei, Sinha, Ayan, Ray, Prabir, Ray, Anuradha

“…Abstract BACKGROUND Exposure to innocuous inhaled foreign antigens such as dust mite and pollen triggers aberrant immune responses in the respiratory tract of…”
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Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung by He, Kun, Hettinga, Angela, Kale, Sagar Laxman, Hu, Sanmei, Xie, Markus M, Dent, Alexander L, Ray, Anuradha, Poholek, Amanda C

“…A Th2 immune response is central to allergic airway inflammation, which afflicts millions worldwide. However, the mechanisms that augment GATA3 expression in…”
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Interleukin-22 controls RSV production in primary human airway epithelial cells by preserving cellular autophagy by Das, Sudipta, Hu, Sanmei, Chen, Jie, St. Croix, Claudette M, Kolls, Jay K., Ray, Anuradha, Ray, Prabir

“…Abstract OBJECTIVE To study the ability of the host protective cytokine interleukin-22 (IL-22) to block productive infection of airway epithelial cells by…”
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Targeting of the surfactant protein A receptor SP-R210L variant by influenza A virus in macrophages. (INM8P.440) by Yang, Linlin, Hu, Sanmei, Chroneos, Zissis

“…Abstract Alveolar macrophages (AM) are critical for controlling IAV infection by limiting virus release and by initiating innate and adaptive immunity…”
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The Surfactant Protein A Receptor SP‐R210 L Variant Medicates Infection and Resolution of Influenza A Virus in the Lung by Yang, Linlin, Hu, Sanmei, Halstead, E Scott, Chroneos, Zissis

“…Abstract only Alveolar macrophages (AM) are critical for controlling influenza virus (IAV) infection by limiting virus release and initiating immunity…”
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1056: GM-CSF PROTECTS FROM SEVERE INFLUENZA INFECTION BY ACCELERATING THE RECOVERY OF LUNG HOMEOSTASIS by Halstead, E. Scott, Umstead, Todd, Davies, Michael, Guo, Weichao, Hu, Sanmei, Chroneos, Zissis

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Influenza induces GM-CSF deficiency: lung-specific overexpression after infection confers protection (INC1P.355) by Halstead, Eric, Guo, Weichao, Yang, Linlin, Hu, Sanmei, Umstead, Todd, Hartshorn, Kevan, White, Mitch, Chroneos, Zissis

“…Abstract GM-CSF is an essential cytokine for normal lung immune homeostasis. In the current studies we examined the role of GM-CSF and its lung-specific…”
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SP-R210 (Myo18A) enhances influenza A virus pathogenicity by alveolar macrophages and dendritic cells in vivo by Fino, Kristin K, Yang, Linlin, Hu, Sanmei, Halstead, Scott E, DiAngelo, Susan L, Silveyra, Patricia, Chroneos, Zissis C

“…Abstract Alveolar macrophages (AMs) are critical for the host response to severe influenza A virus (IAV) infection; IAV is known to cause abortive infection in…”
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Early life exposure to house dust mite allergen prevents experimental allergic asthma requiring mitochondrial H 2 O 2 by Yuan, Huijuan, Chen, Jie, Hu, Sanmei, Oriss, Timothy B, Kale, Sagar Laxman, Das, Sudipta, Nouraie, Seyed M, Ray, Prabir, Ray, Anuradha

“…Immune tolerance to allergens in early-life decreases the risk for asthma in later life. Here we show establishment of stable airway tolerance to the allergen,…”
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Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella Pneumoniae infection by Durrani, Faryal, Phelps, David S., Weisz, Judith, Silveyra, Patricia, Hu, Sanmei, Mikerov, Anatoly N., Floros, Joanna

“…Survival of mice after Klebsiella pneumoniae infection and phagocytosis by alveolar macrophages (AMs), in the presence or absence of ozone (O3) exposure prior…”
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