Search Results - "Hu, Ruifeng"

Deep generative neural network for accurate drug response imputation by Jia, Peilin, Hu, Ruifeng, Pei, Guangsheng, Dai, Yulin, Wang, Yin-Ying, Zhao, Zhongming

“…Drug response differs substantially in cancer patients due to inter- and intra-tumor heterogeneity. Particularly, transcriptome context, especially tumor…”
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6mA-Finder: a novel online tool for predicting DNA N6-methyladenine sites in genomes by Xu, Haodong, Hu, Ruifeng, Jia, Peilin, Zhao, Zhongming

“…Abstract Motivation DNA N6-methyladenine (6 mA) has recently been found as an essential epigenetic modification, playing its roles in a variety of cellular…”
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scGWAS: landscape of trait-cell type associations by integrating single-cell transcriptomics-wide and genome-wide association studies by Jia, Peilin, Hu, Ruifeng, Yan, Fangfang, Dai, Yulin, Zhao, Zhongming

“…The rapid accumulation of single-cell RNA sequencing (scRNA-seq) data presents unique opportunities to decode the genetically mediated cell-type specificity in…”
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Decoding whole-genome mutational signatures in 37 human pan-cancers by denoising sparse autoencoder neural network by Pei, Guangsheng, Hu, Ruifeng, Dai, Yulin, Zhao, Zhongming, Jia, Peilin

“…Millions of somatic mutations have recently been discovered in cancer genomes. These mutations in cancer genomes occur due to internal and external mutagenesis…”
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TSEA-DB: a trait–tissue association map for human complex traits and diseases by Jia, Peilin, Dai, Yulin, Hu, Ruifeng, Pei, Guangsheng, Manuel, Astrid Marilyn, Zhao, Zhongming

“…Abstract Assessing the causal tissues of human traits and diseases is important for better interpreting trait-associated genetic variants, understanding…”
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VISDB: a manually curated database of viral integration sites in the human genome by Tang, Deyou, Li, Bingrui, Xu, Tianyi, Hu, Ruifeng, Tan, Daqiang, Song, Xiaofeng, Jia, Peilin, Zhao, Zhongming

“…Abstract Virus integration into the human genome occurs frequently and represents a key driving event in human disease. Many studies have reported viral…”
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Direct numerical simulation of a stationary spherical particle in fluctuating inflows by Wang, Yuqi, Zhu, Zhengping, Hu, Ruifeng, Shen, Lian

“…Fully resolved direct numerical simulations are conducted to study the effects of fluctuating freestream flow on the drag force and wake characteristics of a…”
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Exploring the Open Innovation Information Spillover Effect: Conceptual Framework Construction and Exploratory Analysis by Hu, Ruifeng, Diao, Xinyi

“…Since its launch, open innovation has been one of the hottest research topics in the field of innovation management. However, most of the current literature…”
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Editorial: Deep learning for disease prediction in next-generation sequencing and biomedical imaging data by Mallik, Saurav, Iwata, Junichi, Hu, Ruifeng, Si, Tapas

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ImmuneApp for HLA-I epitope prediction and immunopeptidome analysis by Xu, Haodong, Hu, Ruifeng, Dong, Xianjun, Kuang, Lan, Zhang, Wenchao, Tu, Chao, Li, Zhihong, Zhao, Zhongming

“…Advances in mass spectrometry accelerates the characterization of HLA ligandome, necessitating the development of efficient methods for immunopeptidomics…”
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Inner-outer decomposition of wall shear stress fluctuations in turbulent channels by Wang, Limin, Hu, Ruifeng

“…•Fluctuating wall shear stress is decomposed into small-scale and large-scale components.•A critical Reynolds number that defines the emergence of universal…”
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Logarithmic-Linear Law of the Streamwise Velocity Variance in Stably Stratified Boundary Layers by Yang, Xiang I. A., Chen, Peng E. S., Hu, Ruifeng, Abkar, Mahdi

“…We exploit Monin–Obukhov similarity theory and Townsend’s attached-eddy hypothesis and arrive at a logarithmic-linear law for the streamwise velocity variance…”
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A Simulation Framework of Unmanned Aerial Vehicles Route Planning Design and Validation for Landslide Monitoring by Xie, Dongmei, Hu, Ruifeng, Wang, Chisheng, Zhu, Chuanhua, Xu, Hui, Li, Qipei

“…Unmanned aerial vehicles (UAVs) have emerged as a highly efficient means of monitoring landslide-prone regions, given the growing concern for urban safety and…”
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The evolution of electric technology in the context of China’s low-carbon transformation: a patent analysis by Hu, Ruifeng, Xu, Weiqiao, Yang, Yalin

“…Purpose Owing to increased energy demands, China has become the world’s top CO2 emitter, with electricity generation accounting for the majority of emissions…”
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Effects of Leading Edge Defect on the Aerodynamic and Flow Characteristics of an S809 Airfoil by Wang, Yan, Zheng, Xiaojing, Hu, Ruifeng, Wang, Ping

“…Unexpected performance degradation occurs in wind turbine blades due to leading edge defect when suffering from continuous impacts with rain drops, hails,…”
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Lipidomic Characterization of Oocytes at Single-Cell Level Using Nanoflow Chromatography-Trapped Ion Mobility Spectrometry-Mass Spectrometry by Zhu, Pujia, Bu, Guowei, Hu, Ruifeng, Ruan, Xianqin, Fu, Rongrong, Zhang, Zhourui, Wan, Qiongqiong, Liu, Xin, Miao, Yiliang, Chen, Suming

“…Mass spectrometry (MS)-based lipidomic has become a powerful tool for studying lipids in biological systems. However, lipidome analysis at the single-cell…”
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PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling by Yao, Bing, Gui, Tao, Zeng, Xiangwei, Deng, Yexuan, Wang, Zhi, Wang, Ying, Yang, Dongjun, Li, Qixiang, Xu, Peipei, Hu, Ruifeng, Li, Xinyu, Chen, Bing, Wang, Jin, Zen, Ke, Li, Haitao, Davis, Melissa J, Herold, Marco J, Pan, Hua-Feng, Jiang, Zhi-Wei, Huang, David C S, Liu, Ming, Ju, Junyi, Zhao, Quan

“…Aberrant changes in epigenetic mechanisms such as histone modifications play an important role in cancer progression. PRMT1 which triggers asymmetric…”
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TarNet: An Evidence-Based Database for Natural Medicine Research by Hu, Ruifeng, Ren, Guomin, Sun, Guibo, Sun, Xiaobo

“…Complex diseases seriously threaten human health. Drug discovery approaches based on "single genes, single drugs, and single targets" are limited in targeting…”
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Angiogenic gene networks are dysregulated in opioid use disorder: evidence from multi-omics and imaging of postmortem human brain by Mendez, Emily F., Wei, Haichao, Hu, Ruifeng, Stertz, Laura, Fries, Gabriel R., Wu, Xizi, Najera, Katherine E., Monterey, Michael D., Lincoln, Christie M., Kim, Joo-won, Moriel, Karla, Meyer, Thomas D., Selvaraj, Sudhakar, Teixeira, Antonio L., Zhao, Zhongming, Xu, Junqian, Wu, Jiaqian, Walss-Bass, Consuelo

“…Opioid use disorder (OUD) is a public health crisis in the U.S. that causes over 50 thousand deaths annually due to overdose. Using next-generation RNA…”
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Effects of sampling frequency on the proper orthogonal decomposition based reconstruction of a wind turbine wake by Wang, Yan, Wang, Liang, Hu, RuiFeng, Kong, LingXuan, Cheng, Jie

“…The effects of sampling frequency on the efficacy of the POD technique for reconstructing the flow field of a wind turbine wake are studied in a neutral…”
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