Search Results - "Hu, Renqiu"

Divergence of Binding, Signaling, and Biological Responses to Recombinant Human Hybrid IFN by Hu, Renqiu, Bekisz, Joseph, Hayes, Mark, Audet, Susette, Beeler, Judy, Petricoin, Emanuel, Zoon, Kathryn

“…Three human IFN-alpha hybrids, HY-1 [IFN-alpha21a(1-75)/alpha2c(76-165)], HY-2 [IFN-alpha21a(1-95)/alpha2c(96-165)], and HY-3…”
Get full text

Prolonged STAT1 Activation Related to the Growth Arrest of Malignant Lymphoma Cells by Interferon-α by Grimley, Philip M., Fang, Hui, Rui, Hallgeir, Petricoin III, Emanuel F., Ray, Subhransu, Dong, Fan, Fields, Karen H., Hu, Renqiu, Zoon, Kathryn C., Audet, Susette, Beeler, Judy

“…Multiple biologic effects of interferon-α (IFN-α), including cell growth inhibition and antiviral protection, are initiated by tyrosine phosphorylation of STAT…”
Get full text

Evidence for multiple binding sites for several components of human lymphoblastoid interferon-alpha by Hu, R, Gan, Y, Liu, J, Miller, D, Zoon, K C

“…The antiproliferative and competitive binding activities of 20 purified components of human lymphoblastoid interferon (IFN)-alpha were compared with that of…”
Get full text

Modulation of Epidermal Growth Factor Receptors by Human α Interferon by Zoon, Kathryn C., Karasaki, Yuji, Dorothy L. Zur Nedden, Hu, Renqiu, Arnheiter, Heinz

“…Treatment of Madin-Darby bovine kidney (MDBK) cells with human interferon (IFN)-α 2 at 37 degrees C results in a dose-dependent inhibition of cell growth and a…”
Get full text

Human IFN-alpha protein engineering: the amino acid residues at positions 86 and 90 are important for antiproliferative activity by Hu, R, Bekisz, J, Schmeisser, H, McPhie, P, Zoon, K

“…Human IFN-alpha is a family of structurally related proteins that exhibit a wide range of antiproliferative activities. To understand the structural basis for…”
Get full text

Amino acid substitutions in loop BC and helix C affect antigenic properties of helix D in hybrid IFN-alpha21a/alpha2c molecules by Schmeisser, Hana, Hu, Renqiu, Kontsek, Peter, Bekisz, Joseph, Zoon, Kathryn

“…We compared the antigenic properties of human interferon-alpha2c (IFN-alpha2c), IFN-alpha21a, hybrids IFN-alpha21a/alpha2c, and their mutants, using a panel of…”
Get more information

Protein engineering of interferon alphas by Hu, Renqiu, Lei, Ke-Jian, Bekisz, Joseph, Zoon, Kathryn C

“…Interferon (IFN)-alphas constitute a family of proteins exhibiting high degree of homology in primary, secondary, and tertiary structure and display a high…”
Get more information

Human IFN-{alpha} Protein Engineering: The Amino Acid Residues at Positions 86 and 90 Are Important for Antiproliferative Activity by Hu, Renqiu, Bekisz, Joseph, Schmeisser, Hana, McPhie, Peter, Zoon, Kathryn

Get full text