Search Results - "Hu, Mengying"

Heterogeneous pseudobulk simulation enables realistic benchmarking of cell-type deconvolution methods by Hu, Mengying, Chikina, Maria

“…Computational cell type deconvolution enables the estimation of cell type abundance from bulk tissues and is important for understanding tissue…”
Get full text

Hepatic macrophages act as a central hub for relaxin-mediated alleviation of liver fibrosis by Hu, Mengying, Wang, Ying, Liu, Zhengsheng, Yu, Zhuo, Guan, Kaiyun, Liu, Mengrui, Wang, Menglin, Tan, Jun, Huang, Leaf

“…Relaxin is an antifibrotic peptide hormone previously assumed to directly reverse the activation of hepatic stellate cells for liver fibrosis resolution. Using…”
Get full text

Relaxin gene delivery mitigates liver metastasis and synergizes with check point therapy by Hu, Mengying, Wang, Ying, Xu, Ligeng, An, Sai, Tang, Yu, Zhou, Xuefei, Li, Jingjing, Liu, Rihe, Huang, Leaf

“…Activated hepatic stellate cell (aHSC)-mediated liver fibrosis is essential to the development of liver metastasis. Here, we discover intra-hepatic scale-up of…”
Get full text

Trapping of Lipopolysaccharide to Promote Immunotherapy against Colorectal Cancer and Attenuate Liver Metastasis by Song, Wantong, Tiruthani, Karthik, Wang, Ying, Shen, Limei, Hu, Mengying, Dorosheva, Oleksandra, Qiu, Kunyu, Kinghorn, Karina A., Liu, Rihe, Huang, Leaf

“…The development and progression of colorectal cancer (CRC) is closely related to gut microbiome. Here, the impact of lipopolysaccharide (LPS), one of the most…”
Get full text

mRNA Delivery of a Bispecific Single‐Domain Antibody to Polarize Tumor‐Associated Macrophages and Synergize Immunotherapy against Liver Malignancies by Wang, Ying, Tiruthani, Karthik, Li, Sirui, Hu, Mengying, Zhong, Guojie, Tang, Yu, Roy, Sourav, Zhang, Lillian, Tan, Jun, Liao, Chengheng, Liu, Rihe

“…Liver malignancies are among the tumor types that are resistant to immune checkpoint inhibition therapy. Tumor‐associated macrophages (TAMs) are highly…”
Get full text

Geometry-dependent skin effects in reciprocal photonic crystals by Fang, Zhening, Hu, Mengying, Zhou, Lei, Ding, Kun

“…Skin effect that all eigenmodes within a frequency range become edge states is dictated by the topological properties of eigenvalues unique in systems. The…”
Get full text

Double-bowl state in photonic Dirac nodal line semimetal by Hu, Mengying, Zhang, Ye, Jiang, Xi, Qiao, Tong, Wang, Qiang, Zhu, Shining, Xiao, Meng, Liu, Hui

“…The past decade has seen a proliferation of topological materials for both insulators and semimetals in electronic systems and classical waves. Topological…”
Get full text

Nanoparticle Delivery of miR-122 Inhibits Colorectal Cancer Liver Metastasis by Sendi, Hossein, Yazdimamaghani, Mostafa, Hu, Mengying, Sultanpuram, Nikhila, Wang, Jie, Moody, Amber S, McCabe, Ellie, Zhang, Jiajie, Graboski, Amanda, Li, Liantao, Rojas, Juan D, Dayton, Paul A, Huang, Leaf, Wang, Andrew Z

“…Liver metastasis is a leading cause of cancer morbidity and mortality. Thus, there has been strong interest in the development of therapeutics that can…”
Get full text

JAX2, an ethanol extract of Hyssopus cuspidatus Boriss, can prevent bronchial asthma by inhibiting MAPK/NF-κB inflammatory signaling by Yuan, Fengjuan, Liu, Rui, Hu, Mengying, Rong, Xiaojuan, Bai, Liping, Xu, Lei, Mao, Yan, Hasimu, Hamulati, Sun, Yuhua, He, Jinhua

“…Hyssopus cuspidatus Boriss has been used to treat bronchial asthma for many years in Uighur medicine. JAX2, an ethanol extract from this plant, has…”
Get full text

A Power-Efficient SAR ADC with Optimized Timing-Redistribution Asynchronous SAR Logic in 40-nm CMOS by Hu, Mengying, Jin, Jing, Guo, Yuekang, Liu, Xiaoming, Zhou, Jianjun

“…This paper presents a power-efficient successive-approximation register (SAR) analog-to-digital converter (ADC) with fast response reference buffer…”
Get full text

Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression by Li, Zhongchi, Low, Vivien, Luga, Valbona, Sun, Janet, Earlie, Ethan, Parang, Bobak, Shobana Ganesh, Kripa, Cho, Sungyun, Endress, Jennifer, Schild, Tanya, Hu, Mengying, Lyden, David, Jin, Wenbing, Guo, Chunjun, Dephoure, Noah, Cantley, Lewis C., Laughney, Ashley M., Blenis, John

“…The systemic metabolic shifts that occur during aging and the local metabolic alterations of a tumor, its stroma and their communication cooperate to establish…”
Get full text

Integration of network pharmacology, transcriptomics and molecular docking reveals two novel hypoglycemic components in snow chrysanthemum by Lv, Qiuyue, Wu, Xinyan, Guan, Yuwen, Lin, Jinrong, Sun, Yuhua, Hu, Mengying, Xiao, Peigen, He, Chunnian, Jiang, Baoping

“…Our previous studies uncovered the glucose-lowering properties of snow chrysanthemum tea, however, the active ingredients and underlying mechanisms were yet to…”
Get full text

Lipid Mediators Metabolic Chaos of Asthmatic Mice Reversed by Rosmarinic Acid by Qin, Tuo, Rong, Xiaojuan, Zhang, Xiaohui, Kong, Lingfei, Kang, Yutong, Liu, Xuanlin, Hu, Mengying, Liang, Handong, Tie, Cai

“…Asthma is a common chronic inflammatory disease of the airways with no known cure. Lipid mediators (LMs) are a kind of inflammatory signaling molecules which…”
Get full text

An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma by Sun, Hanyong, Yang, Weiqin, Tian, Yuan, Zeng, Xuezhen, Zhou, Jingying, Mok, Myth T. S., Tang, Wenshu, Feng, Yu, Xu, Liangliang, Chan, Anthony W. H., Tong, Joanna H., Cheung, Yue-Sun, Lai, Paul B. S., Wang, Hector K. S., Tsang, Shun-Wa, Chow, King-Lau, Hu, Mengying, Liu, Rihe, Huang, Leaf, Yang, Bing, Yang, Pengyuan, To, Ka-Fai, Sung, Joseph J. Y., Wong, Grace L. H., Wong, Vincent W. S., Cheng, Alfred S. L.

“…Obesity increases the risk of hepatocellular carcinoma (HCC) especially in men, but the molecular mechanism remains obscure. Here, we show that an androgen…”
Get full text

Realization of photonic charge-2 Dirac point by engineering super-modes in topological superlattices by Hu, Mengying, Ding, Kun, Qiao, Tong, Jiang, Xi, Wang, Qiang, Zhu, Shining, Liu, Hui

“…Quite recently, an unconventional variety of fourfold linear band degeneracy points has been discovered in certain condensed-matter systems. Contrary to…”
Get full text

A novel electricity consumption forecasting model based on kernel extreme learning machine-with generalized maximum correntropy criterion by Duan, Jiandong, Hou, Zequan, Fang, Shuai, Lu, Wenchao, Hu, Mengying, Tian, Xuan, Wang, Peng, Ma, Wentao

“…Electricity consumption forecasting (ECF) plays a crucial role in the new open electricity market nowadays, and in order to pass the ECF test, the ECF error is…”
Get full text

Predict Ki-67 Positive Cells in H&E-Stained Images Using Deep Learning Independently From IHC-Stained Images by Liu, Yiqing, Li, Xi, Zheng, Aiping, Zhu, Xihan, Liu, Shuting, Hu, Mengying, Luo, Qianjiang, Liao, Huina, Liu, Mubiao, He, Yonghong, Chen, Yupeng

“…To obtain molecular information in slides directly from H&E staining slides, which apparently display morphological information, to show that some differences…”
Get full text

Temporal and spatial distribution of Cenozoic igneous rocks in the South China Sea and its adjacent regions: implications for tectono-magmatic evolution by Hui, GeGe, Li, Sanzhong, Li, Xiyao, Guo, LingLi, Suo, YanHui, Somerville, Ian D., Zhao, Shujuan, Hu, Mengying, Lan, Haoyuan, Zhang, Jian

“…The ocean–continent transition/conjunction zone is a mysterious and significant region in global tectonics and geodynamic evolution. The South China Sea (SCS)…”
Get full text

Dynamic mechanism of tectonic inversion and implications for oil–gas accumulation in the Xihu Sag, East China Sea Shelf Basin: Insights from numerical modelling by Hu, Mengying, Li, Sanzhong, Dai, Liming, Suo, Yanhui, Guo, Lingli, Somerville, Ian, Liu, Ze, Ma, Fangfang, Yu, S.

“…The East China Sea Shelf Basin (ECSSB) lies at the south‐eastern margin of the Eurasian Plate and was affected by the subduction of the Pacific Plate and the…”
Get full text

Strategies targeting tumor immune and stromal microenvironment and their clinical relevance by Hu, Mengying, Huang, Leaf

“…[Display omitted] The critical role of tumor microenvironment (TME) in tumor initiation and development has been well-recognized after more than a century of…”
Get full text