Search Results - "Hu, Junyuan"
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Panax notoginseng Saponins for Treating Coronary Artery Disease: A Functional and Mechanistic Overview
Published in Frontiers in pharmacology (17-10-2017)“…Coronary artery disease (CAD) is a major public health problem and the chief cause of morbidity and mortality worldwide. , a valuable herb in traditional…”
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Utilization of convolutional neural networks to analyze microscopic images for high-throughput screening of mesenchymal stem cells
Published in Open life sciences (10-07-2024)“…This work investigated the high-throughput classification performance of microscopic images of mesenchymal stem cells (MSCs) using a hyperspectral…”
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Epigenetic mechanisms in coronary artery disease: The current state and prospects
Published in Trends in cardiovascular medicine (01-07-2018)“…Coronary artery disease (CAD) is the leading cause of morbidity and mortality. CAD has both genetic and environmental causes. In the past two decades, the…”
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Efficient generation of induced pluripotent stem cell lines from peripheral blood mononuclear cells
Published in Stem cell research (01-06-2023)“…Peripheral blood mononuclear cells (PBMCs) have been widely considered as a more convenient and almost unlimited reprogramming resource, while the…”
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Efficient generation of induced pluripotent stem cell lines from healthy donors’ peripheral blood mononuclear cells of different genders
Published in Stem cell research (01-06-2024)“…Peripheral blood mononuclear cell (PBMC) are recognized as a conveniently collected reprogramming resource. Several methods are available in academia to…”
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Human umbilical cord mesenchymal stromal cells attenuate pulmonary fibrosis via regulatory T cell through interaction with macrophage
Published in Stem cell research & therapy (13-07-2021)“…Pulmonary fibrosis (PF) is a growing clinical problem with limited therapeutic options. Human umbilical cord mesenchymal stromal cell (hucMSC) therapy is being…”
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Interleukin-18-primed human umbilical cord-mesenchymal stem cells achieve superior therapeutic efficacy for severe viral pneumonia via enhancing T-cell immunosuppression
Published in Cell death & disease (28-01-2023)“…Coronavirus disease 2019 (COVID-19) treatments are still urgently needed for critically and severely ill patients. Human umbilical cord-mesenchymal stem cells…”
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A GMP-compliant manufacturing method for Wharton's jelly-derived mesenchymal stromal cells
Published in Stem cell research & therapy (03-05-2024)“…Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) hold great therapeutic potential in regenerative medicine. Therefore, it is crucial to establish a…”
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Unveiling the functional heterogeneity of cytokine-primed human umbilical cord mesenchymal stem cells through single-cell RNA sequencing
Published in Cell & bioscience (26-03-2024)“…Mesenchymal stem cells (MSCs) hold immense promise for use in immunomodulation and regenerative medicine. However, their inherent heterogeneity makes it…”
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A Comprehensive Mass Spectrometry-Based Workflow for Clinical Metabolomics Cohort Studies
Published in Metabolites (24-11-2022)“…As a comprehensive analysis of all metabolites in a biological system, metabolomics is being widely applied in various clinical/health areas for disease…”
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Programmed Cell Death Ligand 1 Is Enriched in Mammary Stem Cells and Promotes Mammary Development and Regeneration
Published in Frontiers in cell and developmental biology (05-11-2021)“…Programmed cell death ligand 1 (PD-L1) is widely expressed in a variety of human tumors, and inhibition of the PD-L1/PD-1 pathway represents one of the most…”
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Human Platelet Lysate Maintains Stemness of Umbilical Cord-Derived Mesenchymal Stromal Cells and Promote Lung Repair in Rat Bronchopulmonary Dysplasia
Published in Frontiers in cell and developmental biology (10-11-2021)“…Mesenchymal stromal cells (MSCs) show potential for treating preclinical models of newborn bronchopulmonary dysplasia (BPD), but studies of their therapeutic…”
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Computationally rational design of metal‐involving halogen bonds with π‐covalency: Structures and bonding analysis
Published in Journal of computational chemistry (30-01-2023)“…Traditional π‐covalent interactions have been proved in the non‐metal halogen bond adducts formed by chloride and halogenated triphenylamine‐based radical…”
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The role of DNA methylation in coronary artery disease
Published in Gene (10-03-2018)“…Epigenetic studies have identified DNA methylation in coronary artery disease (CAD). How the critical genes interact at the cellular level to cause CAD is…”
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Efficacy and safety of oral Panax notoginseng saponins for unstable angina patients: A meta-analysis and systematic review
Published in Phytomedicine (Stuttgart) (01-08-2018)“…Panax notoginseng saponins (PNS) is one of the most important active ingredients in Panax notoginseng, which plays an important role against cardiovascular…”
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Synthesis of P(V)-Stereogenic Phosphorus Compounds via Organocatalytic Asymmetric Condensation
Published in Journal of the American Chemical Society (26-11-2024)“…Enantioenriched phosphorus(V)-stereogenic compounds, featuring a pentavalent phosphorus atom as the stereogenic center, are crucial in various natural…”
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Catalyst Control over S(IV)-stereogenicity via Carbene-derived Sulfinyl Azolium Intermediates
Published in Journal of the American Chemical Society (11-09-2024)“…Stereoselective synthesis utilizing small-molecule catalysts, particularly N-heterocyclic carbene (NHC), has facilitated swift access to enantioenriched…”
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Application of Trichoderma asperellum spore powder helps maintain ionic balance and photosystem II activity in wolfberry in saline soil
Published in Scientia horticulturae (01-11-2024)“…•Trichoderma asperellum blocked root K+ loss in wolfberry under saline stress.•Trichoderma asperellum increased root Na+ exclusion in wolfberry under saline…”
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Engineered porous Co–Ni alloy on carbon cloth as an efficient bifunctional electrocatalyst for glucose electrolysis in alkaline environment
Published in Journal of alloys and compounds (15-05-2020)“…Toward water splitting, the cell voltage is limited by the sluggish anodic oxygen evolution reaction (OER), requiring a much higher overpotential than cathodic…”
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Understanding Alkali Cation-Assisted Ring-Opening Polymerization of Macrocyclic Carbonate: Kinetics and Thermodynamics
Published in Macromolecules (12-09-2023)“…Control over polymerization thermodynamics and kinetics enables the generation of polymers with on-demand properties. This is exemplified by the ring-opening…”
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