Search Results - "Hu, Jun Jacob"

Tandem Payne/Dakin Reaction: A New Strategy for Hydrogen Peroxide Detection and Molecular Imaging by Ye, Sen, Hu, Jun Jacob, Yang, Dan

“…Hydrogen peroxide (H2O2) has been recognized as one of the most significant ROS (reactive oxygen species) in human health and disease. Because of the intrinsic…”
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Fluorescent probes for in vitro and in vivo quantification of hydrogen peroxide by Ye, Sen, Hu, Jun Jacob, Zhao, Qian Angela, Yang, Dan

“…Hydrogen peroxide (H O ) plays essential roles in redox signaling and oxidative stress, and its dynamic concentration is critical to human health and diseases…”
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FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation by Hu, Jun Jacob, Liu, Xing, Xia, Shiyu, Zhang, Zhibin, Zhang, Ying, Zhao, Jingxia, Ruan, Jianbin, Luo, Xuemei, Lou, Xiwen, Bai, Yang, Wang, Junhong, Hollingsworth, L. Robert, Magupalli, Venkat Giri, Zhao, Li, Luo, Hongbo R., Kim, Justin, Lieberman, Judy, Wu, Hao

“…Cytosolic sensing of pathogens and damage by myeloid and barrier epithelial cells assembles large complexes called inflammasomes, which activate inflammatory…”
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HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation by Magupalli, Venkat Giri, Negro, Roberto, Tian, Yuzi, Hauenstein, Arthur V, Di Caprio, Giuseppe, Skillern, Wesley, Deng, Qiufang, Orning, Pontus, Alam, Hasan B, Maliga, Zoltan, Sharif, Humayun, Hu, Jun Jacob, Evavold, Charles L, Kagan, Jonathan C, Schmidt, Florian I, Fitzgerald, Katherine A, Kirchhausen, Tom, Li, Yongqing, Wu, Hao

“…Inflammasomes are supramolecular complexes that play key roles in immune surveillance. This is accomplished by the activation of inflammatory caspases, which…”
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HKOCl‑2 Series of Green BODIPY-Based Fluorescent Probes for Hypochlorous Acid Detection and Imaging in Live Cells by Hu, Jun Jacob, Wong, Nai-Kei, Gu, Qiangshuai, Bai, Xiaoyu, Ye, Sen, Yang, Dan

“…A HKOCl-2 series of new fluorescent probes for hypochlorous acid (HOCl) detection in live cells is reported. The probes exhibit excellent selectivity,…”
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Fluorescent Probe HKSOX‑1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo by Hu, Jun Jacob, Wong, Nai-Kei, Ye, Sen, Chen, Xingmiao, Lu, Ming-Yang, Zhao, Angela Qian, Guo, Yuhan, Ma, Alvin Chun-Hang, Leung, Anskar Yu-Hung, Shen, Jiangang, Yang, Dan

“…Superoxide anion radical (O2 •–) is undoubtedly the most important primary reactive oxygen species (ROS) found in cells, whose formation and fate are…”
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HKOCl-3 : a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay by Hu, Jun Jacob, Wong, Nai-Kei, Lu, Ming-Yang, Chen, Xingmiao, Ye, Sen, Zhao, Angela Qian, Gao, Peng, Yi-Tsun Kao, Richard, Shen, Jiangang, Yang, Dan

“…Ultra-selective and ultra-sensitive probes for hypochlorous acid (HOCl), one of the most poorly understood reactive oxygen species (ROS), are urgently needed…”
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Fluorescent Probes for HOCl Imaging by Hu, Jun Jacob, Ye, Sen, Yang, Dan

“…Small‐molecule fluorescent probes for hypochlorous acid (HOCl), one of the poorly understood reactive oxygen species (ROS), help to unveil HOCl functions in…”
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Tandem Payne/Dakin Reaction: A New Strategy for Hydrogen Peroxide Detection and Molecular Imaging by Ye, Sen, Hu, Jun Jacob, Yang, Dan

“…Hydrogen peroxide (H2O2) has been recognized as one of the most significant ROS (reactive oxygen species) in human health and disease. Because of the intrinsic…”
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Small-Molecule-Based Fluorescent Sensors for Selective Detection of Reactive Oxygen Species in Biological Systems by Bai, Xiaoyu, Ng, Kenneth King-Hei, Hu, Jun Jacob, Ye, Sen, Yang, Dan

“…Reactive oxygen species (ROS) encompass a collection of intricately linked chemical entities characterized by individually distinct physicochemical properties…”
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Molecular Imaging of Peroxynitrite with HKGreen‑4 in Live Cells and Tissues by Peng, Tao, Wong, Nai-Kei, Chen, Xingmiao, Chan, Yee-Kwan, Ho, Derek Hoi-Hang, Sun, Zhenning, Hu, Jun Jacob, Shen, Jiangang, El-Nezami, Hani, Yang, Dan

“…Peroxynitrite (ONOO–), the product of a radical combination reaction of nitric oxide and superoxide, is a potent biological oxidant involved in a broad…”
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The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells by Sen Santara, Sumit, Lee, Dian-Jang, Crespo, Ângela, Hu, Jun Jacob, Walker, Caitlin, Ma, Xiyu, Zhang, Ying, Chowdhury, Sourav, Meza-Sosa, Karla F., Lewandrowski, Mercedes, Zhang, Haiwei, Rowe, Marjorie, McClelland, Arthur, Wu, Hao, Junqueira, Caroline, Lieberman, Judy

“…Natural killer (NK) cells kill infected, transformed and stressed cells when an activating NK cell receptor is triggered 1 . Most NK cells and some innate…”
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HKPerox-1: A Highly Selective and Sensitive Fluorescent Probe for Hydrogen Peroxide Detection in Live Cells by Ye, Sen, Hu, Jun Jacob, Yang, Dan

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88 - HKPerox-1: A Highly Selective and Sensitive Fluorescent Probe for Hydrogen Peroxide Detection in Live Cells by Ye, Sen, Hu, Jun Jacob, Yang, Dan

“…Hydrogen peroxide (H2O2) plays important roles in mediating diverse physiological and pathological responses. Recent research clearly demonstrates that H2O2…”
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SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage by Meza-Sosa, Karla F., Miao, Rui, Navarro, Francisco, Zhang, Zhibin, Zhang, Ying, Hu, Jun Jacob, Hartford, Corrine Corrina R., Li, Xiao Ling, Pedraza-Alva, Gustavo, Pérez-Martínez, Leonor, Lal, Ashish, Wu, Hao, Lieberman, Judy

“…p53, master transcriptional regulator of the genotoxic stress response, controls cell-cycle arrest and apoptosis following DNA damage. Here, we identify a…”
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Publisher Correction: The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells by Sen Santara, Sumit, Lee, Dian-Jang, Crespo, Ângela, Hu, Jun Jacob, Walker, Caitlin, Ma, Xiyu, Zhang, Ying, Chowdhury, Sourav, Meza-Sosa, Karla F., Lewandrowski, Mercedes, Zhang, Haiwei, Rowe, Marjorie, McClelland, Arthur, Wu, Hao, Junqueira, Caroline, Lieberman, Judy

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40 - Novel Selective Fluorescent Probes for Imaging Superoxide, Peroxynitrite, Hypochlorous Acid, Hydrogen Peroxide and Hydroxyl Radical by Wong, Naikei, Jacob Hu, Jun, Peng, Tao, Bai, Xiaoyu, Lu, Mingyang, Ye, Sen, Yang, Dan

“…Remarkable advances of biological understanding have been made on the complex roles of reactive oxygen/nitrogen species (ROS/RNS) both as signaling molecules…”
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Novel Selective Fluorescent Probes for Imaging Superoxide, Peroxynitrite, Hypochlorous Acid, Hydrogen Peroxide and Hydroxyl Radical by Wong, Naikei, Jacob Hu, Jun, Peng, Tao, Bai, Xiaoyu, Lu, Mingyang, Ye, Sen, Yang, Dan

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Correction to “Molecular Imaging of Peroxynitrite with HKGreen‑4 in Live Cells and Tissues” by Peng, Tao, Wong, Nai-Kei, Chen, Xingmiao, Chan, Yee-Kwan, Sun, Zhenning, Hu, Jun Jacob, Shen, Jiangang, El-Nezami, Hani, Yang, Dan

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Correction to “Molecular Imaging of Peroxynitrite with HKGreen‑4 in Live Cells and Tissues” by Peng, Tao, Wong, Nai-Kei, Chen, Xingmiao, Chan, Yee-Kwan, Sun, Zhenning, Hu, Jun Jacob, Shen, Jiangang, El-Nezami, Hani, Yang, Dan

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