Search Results - "Hu, Huantao"
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Cardiac Glycoside Ouabain Exerts Anticancer Activity via Downregulation of STAT3
Published in Frontiers in oncology (30-06-2021)“…Cardiac glycosides are plant-derived steroid-like compounds which have been used for the treatment of cardiovascular diseases. Ouabain, a cardiotonic steroid…”
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Targeting ferroptosis in the maintenance of mitochondrial homeostasis in the realm of septic cardiomyopathy
Published in Current opinion in pharmacology (01-02-2024)“…Septic cardiomyopathy is one of the predominant culprit factors contributing to the rising mortality in patients with severe sepsis. Among various mechanisms…”
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Cardiac-specific overexpression of catalase attenuates lipopolysaccharide-induced cardiac anomalies through reconciliation of autophagy and ferroptosis
Published in Life sciences (1973) (01-09-2023)“…Lipopolysaccharide (LPS) from Gram-negative bacteria is a major contributor to cardiovascular failure, but the signaling mechanisms underlying its stress…”
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Ablation of mitophagy receptor FUNDC1 accentuates septic cardiomyopathy through ACSL4-dependent regulation of ferroptosis and mitochondrial integrity
Published in Free radical biology & medicine (20-11-2024)“…Sepsis evokes compromised myocardial function prompting heart failure albeit target therapy remains dismal. Our study examined the possible role of mitophagy…”
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