Search Results - "Hu, Hongli"
-
1
The role of chromatin loop extrusion in antibody diversification
Published in Nature reviews. Immunology (01-09-2022)“…Cohesin mediates chromatin loop formation across the genome by extruding chromatin between convergently oriented CTCF-binding elements. Recent studies indicate…”
Get full text
Journal Article -
2
Acetylation of PGK1 promotes liver cancer cell proliferation and tumorigenesis
Published in Hepatology (Baltimore, Md.) (01-02-2017)“…Phosphoglycerate kinase 1 (PGK1) is an important enzyme in the metabolic glycolysis pathway. In this study, we observed a significant overexpression of PGK1 in…”
Get full text
Journal Article -
3
Conformational transitions of a neurotensin receptor 1–Gi1 complex
Published in Nature (London) (01-08-2019)“…Neurotensin receptor 1 (NTSR1) is a G-protein-coupled receptor (GPCR) that engages multiple subtypes of G protein, and is involved in the regulation of blood…”
Get full text
Journal Article -
4
Development of an antibody fragment that stabilizes GPCR/G-protein complexes
Published in Nature communications (13-09-2018)“…Single-particle cryo-electron microscopy (cryo-EM) has recently enabled high-resolution structure determination of numerous biological macromolecular…”
Get full text
Journal Article -
5
The fundamental role of chromatin loop extrusion in physiological V(D)J recombination
Published in Nature (London) (26-09-2019)“…The RAG endonuclease initiates Igh V(D)J assembly in B cell progenitors by joining D segments to J H segments, before joining upstream V H segments to DJ H…”
Get full text
Journal Article -
6
Digital Approach to Rotational Speed Measurement Using an Electrostatic Sensor
Published in Sensors (Basel, Switzerland) (04-06-2019)“…In industrial production processes, rotational speed is a key parameter for equipment condition monitoring and fault diagnosis. To achieve rotational speed…”
Get full text
Journal Article -
7
Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex
Published in Cell (24-01-2019)“…Cannabis elicits its mood-enhancing and analgesic effects through the cannabinoid receptor 1 (CB1), a G protein-coupled receptor (GPCR) that signals primarily…”
Get full text
Journal Article -
8
Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex
Published in Cell (23-08-2018)“…The methylation of histone 3 lysine 4 (H3K4) is carried out by an evolutionarily conserved family of methyltransferases referred to as complex of proteins…”
Get full text
Journal Article -
9
Structural Insights into the Dynamic Assembly of a YFV sNS1 Tetramer
Published in Viruses (29-07-2024)“…Yellow fever virus (YFV) infections can cause severe diseases in humans, resulting in mass casualties in Africa and the Americas each year. Secretory NS1…”
Get full text
Journal Article -
10
Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns
Published in Nature communications (05-09-2022)“…The formyl peptide receptor 1 (FPR1) is primarily responsible for detection of short peptides bearing N-formylated methionine (fMet) that are characteristic of…”
Get full text
Journal Article -
11
Mechanism of agonist-induced activation of the human itch receptor MRGPRX1
Published in PLoS biology (22-06-2023)“…Mas-related G-protein-coupled receptors X1-X4 (MRGPRX1-X4) are 4 primate-specific receptors that are recently reported to be responsible for many biological…”
Get full text
Journal Article -
12
ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer
Published in Cell research (01-05-2015)“…F-box and WD repeat domain-containing 7 (FBW7) is the substrate recognition component of the Skpl-Cull-F- box (SCF) ubiquitin ligase complex and functions as a…”
Get full text
Journal Article -
13
Evaluation of the Performance of Capacitance Sensor for Concentration Measurement of Gas/Solid Particles Flow by Coupled Fields
Published in IEEE sensors journal (15-06-2017)“…This paper proposed a real-time dynamic 3-D numerical simulation method to evaluate the performance of capacitance sensor in the concentration measurement of…”
Get full text
Journal Article -
14
The subcortical maternal complex modulates the cell cycle during early mammalian embryogenesis via 14-3-3
Published in Nature communications (15-10-2024)“…The subcortical maternal complex (SCMC) is essential for safeguarding female fertility in mammals. Assembled in oocytes, the SCMC maintains the cleavage of…”
Get full text
Journal Article -
15
An AST-ELM Method for Eliminating the Influence of Charging Phenomenon on ECT
Published in Sensors (Basel, Switzerland) (09-12-2017)“…Electrical capacitance tomography (ECT) is a promising imaging technology of permittivity distributions in multiphase flow. To reduce the effect of charging…”
Get full text
Journal Article -
16
Multisensor Data Fusion Techniques With ELM for Pulverized-Fuel Flow Concentration Measurement in Cofired Power Plant
Published in IEEE transactions on instrumentation and measurement (01-10-2015)“…Due to the phase concentration, measurement of coal/biomass/air three-phase flow is closely associated with the quantity of pollutant discharged and combustion…”
Get full text
Journal Article -
17
Long-Read Genome Sequence Resource of Ascochyta versabilis Causing Leaf Spot Disease in Pseudostellaria heterophylla
Published in Molecular plant-microbe interactions (01-12-2020)“…is the fungal pathogen that causes the severe leaf spot disease of (Miq.) Pax, a vital Chinese herbal plant. Here, we deployed PacBio single-molecule real-time…”
Get full text
Journal Article -
18
Model-free adaptive discrete-time full-order sliding mode constrained control for path following of unmanned surface vessels
Published in International journal of naval architecture and ocean engineering (01-01-2023)“…Considering the dynamic uncertainty, input saturation, and the discrete characteristics of digital control, a practical path following method is proposed for…”
Get full text
Journal Article -
19
A Water Fraction Measurement Method Using Heuristic-Algorithm-Based Electrical Capacitance Tomography Images Post-Processing Technology
Published in IEEE access (2020)“…This paper presents a sectional water fraction measurement method using electrical capacitance tomography (ECT) image. To achieve a desired measurement…”
Get full text
Journal Article -
20
Diversity, Abundance, and Distribution of Wood-Decay Fungi in Major Parks of Hong Kong
Published in Forests (01-10-2020)“…Wood-decay fungi are one of the major threats to the old and valuable trees in Hong Kong and constitute a main conservation and management challenge because…”
Get full text
Journal Article