Search Results - "Hu, Gaizun"

Impacts of High Fructose Diet and Chronic Exercise on Nitric Oxide Synthase and Oxidative Stress in Rat Kidney by Hu, Gaizun, Xu, Lusi, Ito, Osamu

“…Chronic exercise (Ex) exerts antihypertensive and renoprotective effects in rats fed a high fructose diet (HFr). To elucidate the mechanisms, the impacts of an…”
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Loss of sphingosine kinase 2 protects against cisplatin-induced kidney injury by Xie, Dengpiao, Hu, Gaizun, Chen, Chaoling, Ahmadinejad, Fereshteh, Wang, Weili, Li, Pin-Lan, Gewirtz, David A, Li, Ningjun

“…Cisplatin is an established chemotherapeutic drug for treatment of solid-organ cancers and is the primary drug used in the treatment of head and neck cancer;…”
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Chronic Running Exercise Alleviates Early Progression of Nephropathy with Upregulation of Nitric Oxide Synthases and Suppression of Glycation in Zucker Diabetic Rats by Ito, Daisuke, Cao, Pengyu, Kakihana, Takaaki, Sato, Emiko, Suda, Chihiro, Muroya, Yoshikazu, Ogawa, Yoshiko, Hu, Gaizun, Ishii, Tadashi, Ito, Osamu, Kohzuki, Masahiro, Kiyomoto, Hideyasu

“…Exercise training is known to exert multiple beneficial effects including renal protection in type 2 diabetes mellitus and obesity. However, the mechanisms…”
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High Fructose‐Induced Hypertension and Renal Damage Are Exaggerated in Dahl Salt‐Sensitive Rats via Renal Renin‐Angiotensin System Activation by Xu, Lusi, Hu, Gaizun, Qiu, Jiahe, Fan, Yuxuan, Ma, Yixuan, Miura, Takahiro, Kohzuki, Masahiro, Ito, Osamu

“…Background High‐fructose diet (HFr) induces hypertension and renal damage. However, it has been unknown whether the HFr‐induced hypertension and renal damage…”
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Pitavastatin Upregulates Nitric Oxide Synthases in the Kidney of Spontaneously Hypertensive Rats and Wistar–Kyoto Rats by Hu, Gaizun, Ito, Osamu, Rong, Rong, Sakuyama, Akihiro, Miura, Takahiro, Ito, Daisuke, Ogawa, Yoshiko, Kohzuki, Masahiro

“…Abstract BACKGROUND Clinical trials show potent renoprotective effects of pitavastatin (PTV), although the precise mechanism for these renoprotective effects…”
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Angiotensin II upregulates CYP4A isoform expression in the rat kidney through angiotensin II type 1 receptor by Rong, Rong, Hu, Gaizun, Wang, Wanting, Muroya, Yoshikazu, Miura, Takahiro, Ogawa, Yoshiko, Kohzuki, Masahiro, Ito, Osamu

“…•20-Hydroxyeicosatetraenoic acids is catalyzed from arachidonic acid by CYP4A.•Angiotensin II (AngII) chronically increased the CYP4A expression in the rat…”
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Exercise Training Prevents High Fructose-Induced Hypertension and Renal Damages in Male Dahl Salt-Sensitive Rats by XU, LUSI, HU, GAIZUN, QIU, JIAHE, MIURA, TAKAHIRO, YAMAKOSHI, SEIKO, NAMAI-TAKAHASHI, ASAKO, KOHZUKI, MASAHIRO, ITO, OSAMU

“…High-fructose diet (HFr) causes metabolic syndrome, and HFr-induced hypertension and renal damage are exaggerated in Dahl salt-sensitive (DS) rats. Exercise…”
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PS-B07-2: EXERCISE TRAINING PREVENTS HIGH FRUCTOSE-INDUCED HYPERTENSION AND RENAL DAMAGES IN DAHL SALT-SENSITIVE RATS by Xu, Lusi, Hu, Gaizun, Kohzuki, Masahiro, Ito, Osamu

“…Background: High fructose diet (HFr) causes metabolic syndrome, and HFr-induced hypertension and renal damage are exaggerated in Dahl salt-sensitive (DS) rats…”
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Abstract P175: Chronic Exercise Attenuates Blood Pressure Elevation and Albuminuria With Improvement of Renal Lipid Metabolism in High Fructose-fed Rats by Hu, Gaizun, Ito, Osamu, Xu, Lusi

“…Abstract only High fructose diet (HFr) can lead to metabolic disorder, hypertension, and renal disease. Although chronic exercise (Ex) provides various…”
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Characterization and Ischemic Response of Telecytes in the Mouse Renal Medulla by Zou, Yao, Li, Guangbi, Hu, Gaizun, Yuan, Xinxu, Ritter, Joseph K., Li, Pinlan

“…Telocytes are currently defined as a novel type of interstitial (stromal) cells with very long and thin prolongations, and these cells can produce exosomes to…”
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Antihypertensive Action of Exosomes Released from the Renal Medulla after Unclipping of the Renal Artery of 2 Kidney‐1 Clip Hypertension Mice by Hu, Gaizun, Li, Guangbi, Huang, Dandan, Zou, Yao, Yuan, Xinxu, Li, Pin‐lan

“…The renal medulla has been long known to exert antihypertensive action by releasing different bioactive substances. However, so far it remains unknown what is…”
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Kidney-Targeted Delivery of Prolyl Hydroxylase Domain Protein 2 Small Interfering RNA with Nanoparticles Alleviated Renal Ischemia/Reperfusion Injury by Xie, Dengpiao, Wang, Juan, Hu, Gaizun, Chen, Chaoling, Yang, Hu, Ritter, Joseph K, Qu, Yun, Li, Ningjun

“…Inhibition of hypoxia-inducible factor-prolyl hydroxylase (PHD) has been shown to protect against various kidney diseases. However, there are controversial…”
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Exercise Training Prevents High Fructose-Induced Hypertension and Renal Damages in Male Dahl Salt-Sensitive Rats by Xu, Lusi, Hu, Gaizun, Qiu, Jiahe, Miura, Takahiro, Yamakoshi, Seiko, Namai-Takahashi, Asako, Kohzuki, Masahiro, Ito, Osamu

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Cellular senescence as a target to inhibit epithelial‐mesenchymal transition in HK‐2 cells by Xie, Dengpiao, Hu, Gaizun, Chen, Chaoling, Wang, Weili, Gewirtz, David, Li, Ningjun

“…Cellular senescence is a program that induces a stable growth arrest accompanied by metabolic reprogramming, phenotypic changes, increased…”
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Inactivation of Endocannabinoid‐metabolizing Enzyme FAAH Represses TGF‐β1‐induced Epithelial‐mesenchymal Transition in Renal Proximal Tubular Epithelial Cells by Chen, Chaoling, Xie, Dengpiao, Hu, Gaizun, Wang, Weili, Ritter, Joseph, Li, Ningjun

“…Epithelial‐mesenchymal transition (EMT) of proximal tubular epithelial cells plays a very important role in the development of renal fibrosis and progressive…”
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Abstract P150: Chronic Exercise Provides Antihypertensive Effects With Upregulation of Oxidative Stress-Induced Nitric Oxide Upregulation in The Kidney of High-Fructose Fed Rat by Hu, Gaizun, Xu, Lusi, Kohzuki, Masahiro, Ito, Osamu

“…Abstract only Object: The fructose consumption was reported to correlated with increase of oxidative stress, which thereby impair nitric oxide system. Chronic…”
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A4283 High fructose-induced hypertension and renal dysfunction exaggerate in Dahl salt-sensitive rats by Xu, Lusi, Gaizun, Hu, Masahiro, Kohzuki, Osamu, Ito

“…OBJECTIVES:High-fructose diet (HFr) was reported to induce insulin resistance, multiple organ damages and salt-sensitive hypertension. However, it has been…”
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A3921 Chronic exercise provides nitric oxide-mediated antihypertensive and renoprotective effects in high fructose-fed rats by Hu, Gaizun, Xu, Lusi, Kohzuki, Masahiro, Ito, Osamu

“…OBJECTIVES:The over intake of fructose was reported to have strong correlation with metabolic disorder and hypertensive changes via several mechanisms. Nitric…”
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Inhibition of Sphingosine Kinase 2 Attenuated Cisplatin‐induced Nephrotoxicity in Mice by Xie, Dengpiao Li, Hu, Gaizun, Wang, Weili, Li, Pin-Lan, Chen, Chaoling, Li, Ningjun

“…Abstract only Sphingosine‐1‐phosphate (S1P) is a bioactive sphingolipid metabolite and shown to participate in various kidney diseases. S1P is produced by…”
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Renal Protection against Post Ischemia‐reperfusion Injury in Fatty Acid Amide Hydrolase Knockout Mice by Chen, Chaoling, Wang, Weili, Hu, Gaizun, Xie, Dengpiao, Ritter, Joseph, Li, Ningjun

“…Abstract only Renal fibrosis is a typical characteristic of progressive chronic kidney disease (CKD). Current treatment options to slow renal fibrosis are…”
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