Search Results - "Hu, Andy"
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The role of methionine on metabolism, oxidative stress, and diseases
Published in Amino acids (01-12-2017)“…Methionine is an aliphatic, sulfur-containing, essential amino acid, and a precursor of succinyl-CoA, homocysteine, cysteine, creatine, and carnitine. Recent…”
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2
FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib
Published in Journal of experimental & clinical cancer research (09-01-2017)“…Sorafenib, a multi-kinase inhibitor, is used as a standard therapy for advanced hepatocellular carcinoma (HCC). However, complete remission has not been…”
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3
Therapeutic Potential of Amino Acids in Inflammatory Bowel Disease
Published in Nutrients (23-08-2017)“…Inflammatory bowel disease (IBD), which includes both ulcerative colitis and Crohn's disease, is a chronic relapsing inflammation of the gastrointestinal…”
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4
Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation
Published in The Journal of biological chemistry (13-03-2015)“…Autophagy is an intracellular degradation pathway and is considered to be an essential cell survival mechanism. Defects in autophagy are implicated in many…”
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5
l-Glutamine and l-arginine protect against enterotoxigenic Escherichia coli infection via intestinal innate immunity in mice
Published in Amino acids (01-12-2017)“…Dietary glutamine (Gln) or arginine (Arg) supplementation is beneficial for intestinal health; however, whether Gln or Arg may confer protection against…”
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Baicalin modulates NF-κB and NLRP3 inflammasome signaling in porcine aortic vascular endothelial cells Infected by Haemophilus parasuis Causing Glässer’s disease
Published in Scientific reports (16-01-2018)“…Haemophilus parasuis (H. parasuis) can cause vascular inflammatory injury, but the molecular basis of this effect remains unclear. In this study,we…”
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Lentinan modulates intestinal microbiota and enhances barrier integrity in a piglet model challenged with lipopolysaccharide
Published in Food & function (22-01-2019)“…The intestinal microbiota plays a vital role in metabolism, pathogen resistance, and immune development in host cells, and is modifiable by dietary change…”
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The effects of baicalin on piglets challenged with Glaesserella parasuis
Published in Veterinary research (Paris) (14-08-2020)“…Glaesserella parasuis (G. parasuis) causes porcine vascular inflammation and damage. Baicalin is reported to have antioxidant and anti-inflammatory functions…”
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N-Acetylcysteine improves intestinal function in lipopolysaccharides-challenged piglets through multiple signaling pathways
Published in Amino acids (01-12-2017)“…This study determined whether N -acetylcysteine (NAC) could improve intestinal function through phosphatidylinositol-3-kinase (PI3K)/protein kinase B…”
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10
Effect of Baicalin-Aluminum Complexes on Fecal Microbiome in Piglets
Published in International journal of molecular sciences (14-05-2019)“…The gut microbiome has important effects on gastrointestinal diseases. Diarrhea attenuation functions of baicalin (BA) is not clear. Baicalin-aluminum…”
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Activation of the NF-κB and MAPK Signaling Pathways Contributes to the Inflammatory Responses, but Not Cell Injury, in IPEC-1 Cells Challenged with Hydrogen Peroxide
Published in Oxidative medicine and cellular longevity (2020)“…Oxidative stress can lead to intestinal cell injury as well as the induction of inflammation. It is not clear whether inflammation is an important factor…”
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N-Acetylcysteine supplementation alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus
Published in Amino acids (01-12-2017)“…Porcine epidemic diarrhea virus (PEDV) infects the intestine of young pigs, but effective measures for prevention and treatment are lacking. N -Acetylcysteine…”
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Protective Effects of Baicalin on Peritoneal Tight Junctions in Piglets Challenged with Glaesserella parasuis
Published in Molecules (Basel, Switzerland) (26-02-2021)“…( ) causes inflammation and damage to piglets. Whether polyserositis caused by is due to tight junctions damage and the protective effect of baicalin on it…”
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Necroptosis Underlies Hepatic Damage in a Piglet Model of Lipopolysaccharide-Induced Sepsis
Published in Frontiers in immunology (12-03-2021)“…Necroptosis is a newly recognized form of programmed cell death with characteristics of both necrosis and apoptosis. The role of necroptosis in hepatic damage…”
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Methionine restriction on oxidative stress and immune response in dss-induced colitis mice
Published in Oncotarget (04-07-2017)“…A strong correlation exists between inflammatory bowel disease (IBD) and oxidative stress involving alterations of several key signaling pathways. It is known…”
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Effects of Baicalin on piglet monocytes involving PKC-MAPK signaling pathways induced by Haemophilus parasuis
Published in BMC veterinary research (25-03-2019)“…Haemophilus parasuis (HPS) is the causative agent of Glässer's disease, characterized by arthritis, fibrinous polyserositis and meningitis, and resulting in…”
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Baicalin Inhibits Haemophilus Parasuis -Induced High-Mobility Group Box 1 Release during Inflammation
Published in International journal of molecular sciences (27-04-2018)“…( ) can cause Glässer's disease in pigs. However, the molecular mechanism of the inflammation response induced by remains unclear. The high-mobility group box…”
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Functions of pregnane X receptor in self-detoxification
Published in Amino acids (01-12-2017)“…Pregnane X receptor (PXR, NR1I2), a member of the nuclear receptor superfamily, is a crucial regulator of nutrient metabolism and metabolic detoxification such…”
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Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge
Published in Innate immunity (London, England) (01-11-2016)“…Asparagine (Asn), an activator of ornithine decarboxylase (ODC), stimulates cell proliferation in intestinal epithelial cells. We hypothesized that Asn can…”
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Human interstitial cellular model in therapeutics of heart valve calcification
Published in Amino acids (01-12-2017)“…Calcific aortic valve disease is a common, severe heart condition that is currently with no proven, effective drug treatment and requires a surgical valve…”
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