Search Results - "Hsu, Stephen D H"

Biobank-scale methods and projections for sparse polygenic prediction from machine learning by Raben, Timothy G., Lello, Louis, Widen, Erik, Hsu, Stephen D. H.

“…In this paper we characterize the performance of linear models trained via widely-used sparse machine learning algorithms. We build polygenic scores and…”
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Polygenic Health Index, General Health, and Pleiotropy: Sibling Analysis and Disease Risk Reduction by Widen, Erik, Lello, Louis, Raben, Timothy G., Tellier, Laurent C. A. M., Hsu, Stephen D. H.

“…We construct a polygenic health index as a weighted sum of polygenic risk scores for 20 major disease conditions, including, e.g., coronary artery disease,…”
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Quantum Hair from Gravity by Calmet, Xavier, Casadio, Roberto, Hsu, Stephen D H, Kuipers, Folkert

“…We explore the relationship between the quantum state of a compact matter source and of its asymptotic graviton field. For a matter source in an energy…”
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Accurate Genomic Prediction of Human Height by Lello, Louis, Avery, Steven G, Tellier, Laurent, Vazquez, Ana I, de Los Campos, Gustavo, Hsu, Stephen D H

“…We construct genomic predictors for heritable but extremely complex human quantitative traits (height, heel bone density, and educational attainment) using…”
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Sibling validation of polygenic risk scores and complex trait prediction by Lello, Louis, Raben, Timothy G., Hsu, Stephen D. H.

“…We test 26 polygenic predictors using tens of thousands of genetic siblings from the UK Biobank (UKB), for whom we have SNP genotypes, health status, and…”
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Genomic Prediction of 16 Complex Disease Risks Including Heart Attack, Diabetes, Breast and Prostate Cancer by Lello, Louis, Raben, Timothy G., Yong, Soke Yuen, Tellier, Laurent C. A. M., Hsu, Stephen D. H.

“…We construct risk predictors using polygenic scores (PGS) computed from common Single Nucleotide Polymorphisms (SNPs) for a number of complex disease…”
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Genetic architecture of complex traits and disease risk predictors by Yong, Soke Yuen, Raben, Timothy G., Lello, Louis, Hsu, Stephen D. H.

“…Genomic prediction of complex human traits (e.g., height, cognitive ability, bone density) and disease risks (e.g., breast cancer, diabetes, heart disease,…”
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Asymptotic safety, singularities, and gravitational collapse by Casadio, Roberto, Hsu, Stephen D.H., Mirza, Behrouz

“…Asymptotic safety (an ultraviolet fixed point with finite-dimensional critical surface) offers the possibility that a predictive theory of quantum gravity can…”
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Grand unification and enhanced quantum gravitational effects by Calmet, Xavier, Hsu, Stephen D H, Reeb, David

“…In grand unified theories with large numbers of fields, renormalization effects significantly modify the scale at which quantum gravity becomes strong. This in…”
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A brief history of Hawking's information paradox by Calmet, Xavier, Hsu, Stephen D. H.

“…Abstract In this invited review, we describe Hawking's information paradox and a recently proposed resolution of it. Explicit calculations demonstrate the…”
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Automated Online Exam Proctoring by Atoum, Yousef, Liping Chen, Liu, Alex X., Hsu, Stephen D. H., Liu, Xiaoming

“…Massive open online courses and other forms of remote education continue to increase in popularity and reach. The ability to efficiently proctor remote online…”
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Quantum fluctuations in planar domain wall space–times: A possible origin of primordial preferred direction by Wang, Chih-Hung, Wu, Yu-Huei, Hsu, Stephen D.H.

“…We study the gravitational effects of a planar domain wall on quantum fluctuations of a massless scalar field during inflation. By obtaining an exact solution…”
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Determination of nonlinear genetic architecture using compressed sensing by Ho, Chiu Man, Hsu, Stephen D H

“…One of the fundamental problems of modern genomics is to extract the genetic architecture of a complex trait from a data set of individual genotypes and trait…”
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Quantum hair in electrodynamics and gravity by Calmet, Xavier, Hsu, Stephen D. H.

“…We demonstrate the existence of quantum hair in electrodynamics and gravity using effective action techniques. In the case of electrodynamics we use the…”
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Colorful quantum black holes at the LHC by Calmet, Xavier, Gong, Wei, Hsu, Stephen D.H.

“…We examine the LHC phenomenology of quantum black holes in models of TeV gravity. By quantum black holes we mean black holes of the smallest masses and…”
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Macroscopic Superposition States in Isolated Quantum Systems by Buniy, Roman V., Hsu, Stephen D. H.

“…For any choice of initial state and weak assumptions about the Hamiltonian, large isolated quantum systems undergoing Schrödinger evolution spend most of their…”
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Machine Learning Prediction of Biomarkers from SNPs and of Disease Risk from Biomarkers in the UK Biobank by Widen, Erik, Raben, Timothy G, Lello, Louis, Hsu, Stephen D H

“…We use UK Biobank data to train predictors for 65 blood and urine markers such as HDL, LDL, lipoprotein A, glycated haemoglobin, etc. from SNP genotype. For…”
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Instability of quantum de Sitter spacetime by Ho, Chiu Man, Hsu, Stephen D. H.

“…A bstract Quantized fields (e.g., the graviton itself) in de Sitter (dS) spacetime lead to particle production: specifically, we consider a thermal spectrum…”
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Does the BICEP2 observation of cosmological tensor modes imply an era of nearly planckian energy densities? by Ho, Chiu Man, Hsu, Stephen D. H.

“…A bstract BICEP2 observations, interpreted most simply, suggest an era of inflation with energy densities of order (10 16 GeV) 4 , not far below the Planck…”
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Author Correction: Genomic Prediction of 16 Complex Disease Risks Including Heart Attack, Diabetes, Breast and Prostate Cancer by Lello, Louis, Raben, Timothy G., Yong, Soke Yuen, Tellier, Laurent C. A. M., Hsu, Stephen D. H.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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