Search Results - "Hsu, Myriam Y"
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Iron: An Essential Element of Cancer Metabolism
Published in Cells (Basel, Switzerland) (03-12-2020)“…Cancer cells undergo considerable metabolic changes to foster uncontrolled proliferation in a hostile environment characterized by nutrient deprivation, poor…”
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Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter
Published in Cancer research (Chicago, Ill.) (15-10-2017)“…Extracellular acidosis resulting from intense metabolic activities in tumors promotes cancer cell migration, invasion, and metastasis. Although host cells die…”
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NAD+ repletion with niacin counteracts cancer cachexia
Published in Nature communications (03-04-2023)“…Cachexia is a debilitating wasting syndrome and highly prevalent comorbidity in cancer patients. It manifests especially with energy and mitochondrial…”
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4
Flvcr1a deficiency promotes heme-based energy metabolism dysfunction in skeletal muscle
Published in Cell reports (Cambridge) (26-03-2024)“…The definition of cell metabolic profile is essential to ensure skeletal muscle fiber heterogeneity and to achieve a proper equilibrium between the…”
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Phosphoinositide Conversion Inactivates R‐RAS and Drives Metastases in Breast Cancer
Published in Advanced science (01-03-2022)“…Breast cancer is the most prevalent cancer and a major cause of death in women worldwide. Although early diagnosis and therapeutic intervention significantly…”
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Tumour acidosis evaluated in vivo by MRI-CEST pH imaging reveals breast cancer metastatic potential
Published in British journal of cancer (05-01-2021)“…Background Tumour acidosis is considered to play a central role in promoting cancer invasion and migration, but few studies have investigated in vivo how…”
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Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia
Published in EMBO reports (05-04-2022)“…Cachexia is a wasting syndrome characterized by devastating skeletal muscle atrophy that dramatically increases mortality in various diseases, most notably in…”
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Assessing Metabolic Dysregulation in Muscle During Cachexia
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Cancer cachexia is a metabolic disease characterized by a negative energy balance associated with systemic weight loss and poor quality of life.In particular,…”
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Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Cancer cachexia is a devastating syndrome occurring in the majority of terminally ill cancer patients. Notably, skeletal muscle atrophy is a consistent feature…”
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FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy
Published in Cell reports. Medicine (19-12-2023)“…Skeletal muscle atrophy is a hallmark of cachexia, a wasting condition typical of chronic pathologies, that still represents an unmet medical need. Bone…”
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