Search Results - "Hsu, M M"

Long-term safety of ustekinumab in patients with moderate-to-severe psoriasis: final results from 5 years of follow-up by Papp, K.A., Griffiths, C.E.M., Gordon, K., Lebwohl, M., Szapary, P.O., Wasfi, Y., Chan, D., Hsu, M.-C., Ho, V., Ghislain, P.D., Strober, B., Reich, K.

“…Summary Background  Long‐term safety evaluations of biologics are needed to inform patient management decisions. Objectives  To evaluate the safety of…”
Get full text

Ustekinumab for the treatment of moderate‐to‐severe plaque psoriasis in paediatric patients (≥ 6 to < 12 years of age): efficacy, safety, pharmacokinetic and biomarker results from the open‐label CADMUS Jr study by Philipp, S., Menter, A., Nikkels, A.F., Barber, K., Landells, I., Eichenfield, L.F., Song, M., Randazzo, B., Li, S., Hsu, M.‐C., Zhu, Y., DePrimo, S., Paller, A.S.

“…Summary Background Limited options are available for treatment of paediatric psoriasis. Objectives To evaluate the efficacy and safety of ustekinumab in…”
Get full text

The bending strip method for isogeometric analysis of Kirchhoff–Love shell structures comprised of multiple patches by Kiendl, J., Bazilevs, Y., Hsu, M.-C., Wüchner, R., Bletzinger, K.-U.

“…In this paper we present an isogeometric formulation for rotation-free thin shell analysis of structures comprised of multiple patches. The structural patches…”
Get full text

Isogeometric fluid–structure interaction analysis with emphasis on non-matching discretizations, and with application to wind turbines by Bazilevs, Y., Hsu, M.-C., Scott, M.A.

“…► A framework for isogeometric analysis (IGA) fluid–structure interaction (FSI) is proposed. ► The framework is suitable for non-matching discretizations. ►…”
Get full text

3D simulation of wind turbine rotors at full scale. Part I: Geometry modeling and aerodynamics by Bazilevs, Y., Hsu, M.-C., Akkerman, I., Wright, S., Takizawa, K., Henicke, B., Spielman, T., Tezduyar, T. E.

“…In this two‐part paper we present a collection of numerical methods combined into a single framework, which has the potential for a successful application to…”
Get full text

A fully-coupled fluid-structure interaction simulation of cerebral aneurysms by Bazilevs, Y., Hsu, M.-C., Zhang, Y., Wang, W., Liang, X., Kvamsdal, T., Brekken, R., Isaksen, J. G.

“…This paper presents a computational vascular fluid-structure interaction (FSI) methodology and its application to patient-specific aneurysm models of the…”
Get full text

A generalized finite element formulation for arbitrary basis functions: From isogeometric analysis to XFEM by Benson, D. J., Bazilevs, Y., De Luycker, E., Hsu, M.-C., Scott, M., Hughes, T. J. R., Belytschko, T.

“…Many of the formulations of current research interest, including iosogeometric methods and the extended finite element method, use nontraditional basis…”
Get full text

3D simulation of wind turbine rotors at full scale. Part II: Fluid-structure interaction modeling with composite blades by Bazilevs, Y., Hsu, M.-C., Kiendl, J., Wüchner, R., Bletzinger, K.-U.

“…In this two‐part paper, we present a collection of numerical methods combined into a single framework, which has the potential for a successful application to…”
Get full text

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B by Johanns, M., Lai, Y.-C., Hsu, M.-F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M, Rider, M H

“…Biguanides such as metformin have previously been shown to antagonize hepatic glucagon-stimulated cyclic AMP (cAMP) signalling independently of AMP-activated…”
Get full text

Blended isogeometric shells by Benson, D.J., Hartmann, S., Bazilevs, Y., Hsu, M.-C., Hughes, T.J.R.

“…We propose a new isogeometric shell formulation that blends Kirchhoff–Love theory with Reissner–Mindlin theory. This enables us to reduce the size of equation…”
Get full text

A large deformation, rotation-free, isogeometric shell by Benson, D.J., Bazilevs, Y., Hsu, M.-C., Hughes, T.J.R.

“…Conventional finite shell element formulations use rotational degrees of freedom to describe the motion of the fiber in the Reissner–Mindlin shear deformable…”
Get full text

Computational fluid–structure interaction: methods and application to a total cavopulmonary connection by Bazilevs, Yuri, Hsu, M.-C., Benson, D. J., Sankaran, S., Marsden, A. L.

“…The Fontan procedure is a surgery that is performed on single-ventricle heart patients, and, due to the wide range of anatomies and variations among patients,…”
Get full text

Improving stability of stabilized and multiscale formulations in flow simulations at small time steps by Hsu, M.-C., Bazilevs, Y., Calo, V.M., Tezduyar, T.E., Hughes, T.J.R.

“…The objective of this paper is to show that use of the element-vector-based definition of stabilization parameters, introduced in [T.E. Tezduyar, Computation…”
Get full text

Extension of ustekinumab maintenance dosing interval in moderate‐to‐severe psoriasis: results of a phase IIIb, randomized, double‐blinded, active‐controlled, multicentre study (PSTELLAR) by Blauvelt, A., Ferris, L.K., Yamauchi, P.S., Qureshi, A., Leonardi, C.L., Farahi, K., Fakharzadeh, S., Hsu, M.‐C., Li, S., Chevrier, M., Smith, K., Goyal, K., Chen, Y., Muñoz‐Elías, E.J., Callis Duffin, K.

“…Summary Background Phase III studies showed that some patients maintained response for ≥ 6 months following ustekinumab discontinuation. Objectives To assess…”
Get full text

COVID-19 Among US Dialysis Patients: Risk Factors and Outcomes From a National Dialysis Provider by Hsu, Caroline M., Weiner, Daniel E., Aweh, Gideon, Miskulin, Dana C., Manley, Harold J., Stewart, Carol, Ladik, Vlad, Hosford, John, Lacson, Edward C., Johnson, Douglas S., Lacson, Eduardo

“…During the coronavirus disease 2019 (COVID-19) pandemic, patients receiving maintenance dialysis are a highly vulnerable population due to their comorbidities…”
Get full text

Gut to Brain Dysbiosis: Mechanisms Linking Western Diet Consumption, the Microbiome, and Cognitive Impairment by Noble, Emily E, Hsu, Ted M, Kanoski, Scott E

“…Consumption of a Western Diet (WD) that is high in saturated fat and added sugars negatively impacts cognitive function, particularly mnemonic processes that…”
Get full text

X-FEM in isogeometric analysis for linear fracture mechanics by De Luycker, E., Benson, D. J., Belytschko, T., Bazilevs, Y., Hsu, M. C.

“…The extended finite element method (X‐FEM) has proven to be an accurate, robust method for solving problems in fracture mechanics. X‐FEM has typically been…”
Get full text

A computational procedure for prebending of wind turbine blades by Bazilevs, Y., Hsu, M.-C., Kiendl, J., Benson, D.J.

“…SUMMARY Prebending of wind turbine blades constitutes a viable engineering solution to the problem of tower clearance, that is, ensuring that during wind…”
Get full text

A rapid and efficient isogeometric design space exploration framework with application to structural mechanics by Benzaken, J., Herrema, A.J., Hsu, M.-C., Evans, J.A.

“…In this paper, we present an isogeometric analysis framework for design space exploration. While the methodology is presented in the setting of structural…”
Get full text

Nuclear trafficking of the epidermal growth factor receptor family membrane proteins by Wang, Y-N, Yamaguchi, H, Hsu, J-M, Hung, M-C

“…Multiple membrane-bound receptor tyrosine kinases (RTKs), such as the epidermal growth factor receptor (EGFR) and ErbB-2, have been reported to be localized in…”
Get full text