Search Results - "Hsu, Kai‐Cheng"

Incidence of acute kidney injury in COVID-19 infection: a systematic review and meta-analysis by Chen, Yih-Ting, Shao, Shih-Chieh, Hsu, Cheng-Kai, Wu, I-Wen, Hung, Ming-Jui, Chen, Yung-Chang

“…Keywords: Acute kidney injury, COVID-19, Incidence, Meta-analysis…”
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The role of ubiquitin-specific peptidases in cancer progression by Young, Ming-Jer, Hsu, Kai-Cheng, Lin, Tony Eight, Chang, Wen-Chang, Hung, Jan-Jong

“…Protein ubiquitination is an important mechanism for regulating the activity and levels of proteins under physiological conditions. Loss of regulation by…”
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iGEMDOCK: a graphical environment of enhancing GEMDOCK using pharmacological interactions and post-screening analysis by Hsu, Kai-Cheng, Chen, Yen-Fu, Lin, Shen-Rong, Yang, Jinn-Moon

“…Pharmacological interactions are useful for understanding ligand binding mechanisms of a therapeutic target. These interactions are often inferred from a set…”
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Structural Insights into the Cytotoxic Mechanism of Vibrio parahaemolyticus PirAvp and PirBvp Toxins by Lin, Shin-Jen, Hsu, Kai-Cheng, Wang, Hao-Ching

“…In aquaculture, shrimp farming is a popular field. The benefits of shrimp farming include a relatively short grow-out time, high sale price, and good cost…”
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Acute kidney disease stage predicts outcome of patients on extracorporeal membrane oxygenation support by Hsu, Cheng-Kai, Wu, I-Wen, Chen, Yih-Ting, Tsai, Tsung-Yu, Tsai, Feng-Chun, Fang, Ji-Tseng, Chen, Yung-Chang

“…The mortality rate of patients on extracorporeal membrane oxygenation (ECMO), especially those patients that develop acute kidney injury (AKI) is high. Acute…”
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In silico identification of a novel Cdc2‐like kinase 2 (CLK2) inhibitor in triple negative breast cancer by Huang, Cheng‐Chiao, Hsu, Chia‐Ming, Chao, Min‐Wu, Hsu, Kai‐Cheng, Lin, Tony Eight, Yen, Shih‐Chung, Tu, Huang‐Ju, Pan, Shiow‐Lin

“…Dysregulation of RNA splicing processes is intricately linked to tumorigenesis in various cancers, especially breast cancer. Cdc2‐like kinase 2 (CLK2), an…”
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Performance of urinary C–C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis by Chen, Yih-Ting, Pan, Heng-Chih, Hsu, Cheng-Kai, Sun, Chiao-Yin, Chen, Chun-Yu, Chen, Yi-Hung, Hsu, Heng-Jung, Wu, I-Wen, Wu, Vin-Cent, Hoste, Eric

“…Background Urinary C-C motif chemokine ligand 14 (CCL14) has been described as an effective marker for delayed recovery of acute kidney injury (AKI), yet its…”
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Anti-Inflammatory and Tau Phosphorylation-Inhibitory Effects of Eupatin by Chou, Ching-Hsuan, Hsu, Kai-Cheng, Lin, Tony Eight, Yang, Chia-Ron

“…Alzheimer's disease (AD), which is among the most prevalent neurodegenerative diseases, manifests as increasing memory loss and cognitive decline. Tau…”
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In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction by Lu, Chih-Hao, Chung, Wei-Min, Tsai, Chun-Hao, Cheng, Ju-Chien, Hsu, Kai-Cheng, Tzeng, Huey-En

“…Targeting the programmed cell death protein 1/programmed cell death ligand 1 (PD-1/PD-L1) axis with monoclonal antibodies (mAbs) represents a crucial…”
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An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors by Lin, Tony Eight, Yen, Dyan, HuangFu, Wei‐Chun, Wu, Yi‐Wen, Hsu, Jui‐Yi, Yen, Shih‐Chung, Sung, Tzu‐Ying, Hsieh, Jui‐Hua, Pan, Shiow‐Lin, Yang, Chia‐Ron, Huang, Wei‐Jan, Hsu, Kai‐Cheng

“…The identification of an effective inhibitor is an important starting step in drug development. Unfortunately, many issues such as the characterization of…”
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Model-based optimization approaches for precision medicine: A case study in presynaptic dopamine overactivity by Hsu, Kai-Cheng, Wang, Feng-Sheng

“…Precision medicine considers an individual's unique physiological characteristics as strongly influential in disease vulnerability and in response to specific…”
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Preparation of naphthalenes via Pd‐catalyzed annulation of 5‐(2‐bromophenyl)pent‐3‐en‐1‐ynes under Suzuki‐Miyaura coupling conditions by Hsu, Cheng‐Kai, Liu, Yi‐Hung, Liu, Shiuh‐Tzung

“…Highly substituted naphthalene derivatives were prepared via palladium‐catalyzed reaction of 5‐(2‐bromophenyl)pent‐3‐en‐1‐ynes with arylboronic acids…”
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CHA2DS2-VASc score as an independent outcome predictor in patients hospitalized with acute ischemic stroke by Su, Chun-Hung, Lo, Chien-Hsien, Chen, Hsin-Hung, Tsai, Chin-Feng, Yip, Hei-Tung, Hsu, Kai-Cheng, Hsu, Chung Y, Kao, Chia-Hung

“…Purpose Atrial fibrillation (AF) is a significant independent risk factor for 1-year mortality in patients with first acute ischemic stroke (AIS). The…”
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Machine learning approaches for biomarker discovery to predict large-artery atherosclerosis by Sun, Ting-Hsuan, Wang, Chia-Chun, Wu, Ya-Lun, Hsu, Kai-Cheng, Lee, Tsong-Hai

“…Large-artery atherosclerosis (LAA) is a leading cause of cerebrovascular disease. However, LAA diagnosis is costly and needs professional identification. Many…”
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Renal function is associated with one-month and one-year mortality in patients with intracerebral hemorrhage by Wang, I-Kuan, Yen, Tzung-Hai, Tsai, Chon-Haw, Sun, Yu, Chang, Wei-Lun, Chen, Po-Lin, Lai, Ta-Chang, Yeh, Po-Yen, Wei, Cheng-Yu, Lin, Cheng-Li, Hsu, Kai-Cheng, Li, Chi-Yuan, Sung, Fung-Chang, Hsu, Chung Y

“…This study evaluated short-term (1-month) and long-term (1-year) mortality risks associated with the glomerular filtration rate (eGFR) on admission for…”
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Increased risk of cirrhosis and its decompensation in chronic hepatitis C patients with new‐onset diabetes: A nationwide cohort study by Huang, Yi‐Wen, Yang, Sien‐Sing, Fu, Szu‐Chieh, Wang, Ting‐Chuan, Hsu, Cheng‐Kai, Chen, Ding‐Shinn, Hu, Jui‐Ting, Kao, Jia‐Horng

“…The effect of diabetes on cirrhosis, its decompensation, and their time relationship in chronic hepatitis C (CHC) patients remains unclear. We conducted a…”
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5‑Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer’s Disease Phenotypes by Lee, Hsueh-Yun, Fan, Sheng-Jun, Huang, Fang-I, Chao, Hsin-Yi, Hsu, Kai-Cheng, Lin, Tony Eight, Yeh, Teng-Kuang, Lai, Mei-Jung, Li, Yu-Hsuan, Huang, Hsiang-Ling, Yang, Chia-Ron, Liou, Jing-Ping

“…This paper reports the development of a series of 5-aroylindolyl-substituted hydroxamic acids…”
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Dibenzofuran, 4-Chromanone, Acetophenone, and Dithiecine Derivatives: Cytotoxic Constituents from Eupatorium fortunei by Chang, Chun-Hao, Wu, Semon, Hsu, Kai-Cheng, Huang, Wei-Jan, Chen, Jih-Jung

“…Five new compounds, eupatodibenzofuran A (1), eupatodibenzofuran B (2), 6-acetyl-8-methoxy-2,2-dimethylchroman-4-one (3), eupatofortunone (4), and…”
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Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach by Hsu, Kai-Cheng, Liu, Chang-Yi, Lin, Tony Eight, Hsieh, Jui-Hua, Sung, Tzu-Ying, Tseng, Hui-Ju, Yang, Jinn-Moon, Huang, Wei-Jan

“…Histone deacetylases (HDAC) contain eighteen isoforms that can be divided into four classes. Of these isoform enzymes, class IIa (containing HDAC4, 5, 7 and 9)…”
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USP24 promotes drug resistance during cancer therapy by Wang, Shao-An, Young, Ming-Jer, Wang, Yi-Chang, Chen, Shu-Hui, Liu, Chia-Yu, Lo, Yao-An, Jen, Hung-Hsiang, Hsu, Kai-Cheng, Hung, Jan-Jong

“…Drug resistance has remained an important issue in the treatment and prevention of various diseases, including cancer. Herein, we found that USP24 not only…”
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