Search Results - "Hsu, Jui‐Ling"
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What Prompts Small and Medium Enterprises to Engage in Corporate Social Responsibility? A Study from Taiwan
Published in Corporate social-responsibility and environmental management (01-09-2012)“…ABSTRACT This paper applies the innovation diffusion theory to analyze the impact of perceptive characteristics on the willingness of small and medium…”
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Mechanistic study of dual‐function inhibitors targeting topoisomerase II and Rad51‐mediated DNA repair pathway against castration‐resistant prostate cancer
Published in The Prostate (01-12-2023)“…BackgroundCastration‐resistant prostate cancer (CRPC) is refractory to hormone treatment and the therapeutic options are continuously advancing. This study…”
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3
Ascleposide, a natural cardenolide, induces anticancer signaling in human castration‐resistant prostatic cancer through Na+/K+‐ATPase internalization and tubulin acetylation
Published in The Prostate (01-03-2020)“…Background Cardiac glycosides, which inhibit Na+/K+‐ATPase, display inotropic effects for the treatment of congestive heart failure and cardiac arrhythmia…”
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4
A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin‐induced apoptosis in castration‐resistant prostate cancer
Published in The Prostate (01-05-2024)“…Background Metastatic castration‐resistant prostate cancer (CRPC), the most refractory prostate cancer, inevitably progresses and becomes unresponsive to…”
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Autophagic Activation and Decrease of Plasma Membrane Cholesterol Contribute to Anticancer Activities in Non-Small Cell Lung Cancer
Published in Molecules (Basel, Switzerland) (01-10-2021)“…Non-small cell lung cancer (NSCLC), an aggressive subtype of pulmonary carcinomas with high mortality, accounts for 85% of all lung cancers. Drug resistance…”
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Diploid and tetraploid genomes of Acorus and the evolution of monocots
Published in Nature communications (20-06-2023)“…Monocots are a major taxon within flowering plants, have unique morphological traits, and show an extraordinary diversity in lifestyle. To improve our…”
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Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells
Published in Frontiers in pharmacology (10-11-2020)“…Hepatocellular carcinoma (HCC) is the most common primary liver malignancy in adults and accounts for 85-90% of all primary liver cancer. Based on the…”
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The Combination of MK-2206 and WZB117 Exerts a Synergistic Cytotoxic Effect Against Breast Cancer Cells
Published in Frontiers in pharmacology (06-11-2019)“…Breast cancer is the most commonly diagnosed cancer and the second leading cause of cancer death in women. Hormone receptor-positive breast cancer is usually…”
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Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies
Published in Molecules (Basel, Switzerland) (16-12-2020)“…Chalcones are responsible for biological activity throughout fruits, vegetables, and medicinal plants in preventing and treating a variety of…”
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Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling
Published in Frontiers in oncology (07-08-2020)“…Combination therapies that display cancer-killing activities through either coexistent targeting of several cellular factors or more efficient suppression of a…”
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The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis
Published in Molecules (Basel, Switzerland) (25-06-2020)“…Because conventional chemotherapy is not sufficiently effective against prostate cancer, various examinations have been performed to identify anticancer…”
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Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells-Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy
Published in International journal of molecular sciences (02-04-2020)“…Various derivatives that mimic ceramide structures by introducing a triazole to connect the aminodiol moiety and long alkyl chain have been synthesized and…”
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Para-Toluenesulfonamide Induces Anti-tumor Activity Through Akt-Dependent and -Independent mTOR/p70S6K Pathway: Roles of Lipid Raft and Cholesterol Contents
Published in Frontiers in pharmacology (13-11-2018)“…Castration-resistant prostate cancer (CRPC) cells can resist many cellular stresses to ensure survival. There is an unmet medical need to fight against the…”
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Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Cell Death Against Human Non-Small Cell Lung Cancers
Published in International journal of molecular sciences (05-08-2020)“…Non-small cell lung cancer (NSCLC) accounts about 80% of all lung cancers. More than two-thirds of NSCLC patients have inoperable, locally advanced or…”
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NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells
Published in PloS one (05-11-2014)“…NPRL-Z-1 is a 4β-[(4"-benzamido)-amino]-4'-O-demethyl-epipodophyllotoxin derivative. Previous reports have shown that NPRL-Z-1 possesses anticancer activity…”
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Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycle
Published in PloS one (27-01-2014)“…In the past decade, there has been a profound increase in the number of studies revealing that cardenolide glycosides display inhibitory activity on the growth…”
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Organic dyes incorporating 9,10-dihydrophenanthrene moiety for dye-sensitized solar cells
Published in Molecular Crystals and Liquid Crystals (23-05-2020)“…A series of new dipolar organic dyes containing 9,10-dihydrophenanthrene has been synthesized as sensitizers for the application in dye-sensitized solar cells…”
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Phosphodiesterase Type 5 (PDE5) Inhibitors Sensitize Topoisomerase II Inhibitors in Killing Prostate Cancer Through PDE5-Independent Impairment of HR and NHEJ DNA Repair Systems
Published in Frontiers in oncology (17-01-2019)“…Human castration-resistant prostate cancer (CRPC) is a significant target of clinical research. The use of DNA-damaging agents has a long history in cancer…”
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Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult
Published in Biochemical pharmacology (15-03-2007)“…Hepatocellular carcinoma is a very common malignancy and is chemoresistant to currently available chemotherapeutic agents. Endoplasmic reticulum (ER)…”
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Inhibitory effect of berberine on the invasion of human lung cancer cells via decreased productions of urokinase-plasminogen activator and matrix metalloproteinase-2
Published in Toxicology and applied pharmacology (01-07-2006)“…Berberine, a compound isolated from medicinal herbs, has been reported with many pharmacological effects related to anti-cancer and anti-inflammation…”
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