Search Results - "Hsu, Horng‐Chaung"
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Transforming growth factor β1 enhances heme oxygenase 1 expression in human synovial fibroblasts by inhibiting microRNA 519b synthesis
Published in PloS one (19-04-2017)“…Osteoarthritis (OA) is manifested by synovial inflammation and cartilage destruction that is directly linked to synovitis, joint swelling and pain. In the…”
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2
A model‐based tracking method for measuring 3D dynamic joint motion using an alternating biplane x‐ray imaging system
Published in Medical physics (Lancaster) (01-08-2018)“…Purposes To propose a new model‐based tracking method for measuring three‐dimensional (3D) dynamic joint kinematics using a clinical alternating biplane x‐ray…”
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3
Osteochondral Tissue Regeneration Using a Tyramine-Modified Bilayered PLGA Scaffold Combined with Articular Chondrocytes in a Porcine Model
Published in International journal of molecular sciences (15-01-2019)“…Repairing damaged articular cartilage is challenging due to the limited regenerative capacity of hyaline cartilage. In this study, we fabricated a bilayered…”
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4
Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-10-2012)“…Objective Thrombin is a key factor involved in the stimulation of fibrin deposition, angiogenesis, and proinflammatory processes. Abnormalities in these…”
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5
Enzyme-crosslinked gene-activated matrix for the induction of mesenchymal stem cells in osteochondral tissue regeneration
Published in Acta biomaterialia (01-11-2017)“…[Display omitted] The development of osteochondral tissue engineering is an important issue for the treatment of traumatic injury or aging associated joint…”
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Effects of computer-assisted navigation versus conventional total knee arthroplasty on the levels of inflammation markers: A prospective study
Published in PloS one (14-05-2018)“…Total knee arthroplasty (TKA) is a well-established modality for the treatment of advanced knee osteoarthritis (OA). However, the detrimental effects of…”
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Resistin promotes tumor metastasis by down-regulation of miR-519d through the AMPK/p38 signaling pathway in human chondrosarcoma cells
Published in Oncotarget (01-01-2015)“…Resistin is a recently discovered adipocyte-secreting adipokine, which may play a critical role in modulating cancer pathogenesis. Chondrosarcoma is a highly…”
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8
Makoplasty medial unicondylar knee replacement: Correction or postoperative angle matters?
Published in The international journal of medical robotics + computer assisted surgery (01-04-2022)“…Introduction Various considerations prevail around optimal postoperative varus deformity, correction angle and physiological constitutional varus deformity…”
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9
Integration of statistical shape modeling and alternating interpolation-based model tracking technique for measuring knee kinematics in vivo using clinical interleaved bi-plane fluoroscopy
Published in PeerJ (San Francisco, CA) (14-06-2023)“…A 2D fluoroscopy/3D model-based registration with statistical shape modeling (SSM)-reconstructed subject-specific bone models will help reduce radiation…”
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Anti-neuroinflammatory effects of the calcium channel blocker nicardipine on microglial cells: implications for neuroprotection
Published in PloS one (12-03-2014)“…Nicardipine is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke,…”
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11
Continuous Passive Motion Promotes and Maintains Chondrogenesis in Autologous Endothelial Progenitor Cell-Loaded Porous PLGA Scaffolds during Osteochondral Defect Repair in a Rabbit Model
Published in International journal of molecular sciences (10-01-2019)“…Continuous passive motion (CPM) is widely used after total knee replacement. In this study, we investigated the effect of CPM combined with cell-based…”
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12
Adiponectin increases BMP-2 expression in osteoblasts via AdipoR receptor signaling pathway
Published in Journal of cellular physiology (01-08-2010)“…Adiponectin is a protein hormone secreted predominantly by differentiated adipocytes and involved in energy homeostasis. Bone morphogenetic protein (BMP) plays…”
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13
Osteopontin increases migration and MMP-9 up-regulation via αvβ3 integrin, FAK, ERK, and NF-κB-dependent pathway in human chondrosarcoma cells
Published in Journal of cellular physiology (01-10-2009)“…Tumor malignancy is associated with several features such as proliferation ability and frequency of metastasis. Osteopontin (OPN), which abundantly expressed…”
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14
Intra-articular injection of N-acetylglucosamine and hyaluronic acid combined with PLGA scaffolds for osteochondral repair in rabbits
Published in PloS one (31-12-2018)“…Repairing damaged articular cartilage is particularly challenging because of the limited ability of cartilage to perform self-repair. Intra-articular…”
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15
Thrombin Promotes Matrix Metalloproteinase-13 Expression through the PKCδ/c-Src/EGFR/PI3K/Akt/AP-1 Signaling Pathway in Human Chondrocytes
Published in Mediators of Inflammation (01-01-2013)“…Thrombin is a key mediator of fibrin deposition, angiogenesis, and proinflammatory processes. Abnormalities in these processes are primary features of…”
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16
Peptidoglycan Enhances IL-6 Production in Human Synovial Fibroblasts via TLR2 Receptor, Focal Adhesion Kinase, Akt, and AP-1- Dependent Pathway
Published in The Journal of immunology (1950) (15-08-2009)“…Peptidoglycan (PGN), the major component of the cell wall of Gram-positive bacteria, activates the innate immune system of the host and induces the release of…”
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17
Pro-Inflammatory Stimuli Influence Expression of Intercellular Adhesion Molecule 1 in Human Anulus Fibrosus Cells through FAK/ERK/GSK3 and PKCδ Signaling Pathways
Published in International journal of molecular sciences (25-12-2018)“…Intervertebral disc (IVD) degeneration and disc herniation are major causes of lower back pain, which involve the presence of inflammatory mediators and tissue…”
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18
CCN3 increases cell motility and MMP-13 expression in human chondrosarcoma through integrin-dependent pathway
Published in Journal of cellular physiology (01-12-2011)“…Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant metastasis. Chondrosarcoma shows a predilection…”
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Resistin protects against 6-hydroxydopamine-induced cell death in dopaminergic-like MES23.5 cells
Published in Journal of cellular physiology (01-03-2013)“…Resistin is originally reported as an adipose tissue‐specific hormone and is thought to represent a link between obesity and insulin‐resistant diabetes…”
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20
Strategies for obstacle crossing in older adults with high and low risk of falling
Published in Journal of Physical Therapy Science (01-05-2016)“…[Purpose] Tripping is a frequent cause of falls among aging adults. Appropriate limb movements while negotiating obstacles are critical to trip avoidance. The…”
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