Search Results - "Hsu, Christy"
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CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells
Published in Blood (04-02-2021)“…A number of clinically validated drugs have been developed by repurposing the CUL4-DDB1-CRBN-RBX1 (CRL4CRBN) E3 ubiquitin ligase complex with molecular glue…”
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Journal Article -
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Genetic and pharmacological interrogation of cancer vulnerability using a multiplexed cell line screening platform
Published in Communications biology (02-07-2021)“…The multiplexed cancer cell line screening platform PRISM demonstrated its utility in testing hundreds of cell lines in a single run, possessing the potential…”
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Journal Article