Search Results - "Hsiung, Chia‐Ni"

Population structure of Han Chinese in the modern Taiwanese population based on 10,000 participants in the Taiwan Biobank project by Chen, Chien-Hsiun, Yang, Jenn-Hwai, Chiang, Charleston W K, Hsiung, Chia-Ni, Wu, Pei-Ei, Chang, Li-Ching, Chu, Hou-Wei, Chang, Josh, Song, I-Wen, Yang, Show-Ling, Chen, Yuan-Tsong, Liu, Fu-Tong, Shen, Chen-Yang

“…The Taiwan Biobank (TWB) aims to build a nationwide research database that integrates genomic/epigenomic profiles, lifestyle patterns, dietary habits,…”
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A functional variant near XCL1 gene improves breast cancer survival via promoting cancer immunity by Chou, Wen‐Cheng, Hsiung, Chia‐Ni, Chen, Wei‐Ting, Tseng, Ling‐Ming, Wang, Hui‐Chun, Chu, Hou‐Wei, Hou, Ming‐Feng, Yu, Jyh‐Cherng, Shen, Chen‐Yang

“…Most genome‐wide association studies (GWASs) identify genetic variants for breast cancer occurrence. In contrast, few are for recurrence and mortality. We…”
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Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1 by Cai, Qiuyin, Zhang, Ben, Sung, Hyuna, Low, Siew-Kee, Kweon, Sun-Seog, Lu, Wei, Shi, Jiajun, Long, Jirong, Wen, Wanqing, Choi, Ji-Yeob, Noh, Dong-Young, Shen, Chen-Yang, Matsuo, Keitaro, Teo, Soo-Hwang, Kim, Mi Kyung, Khoo, Ui Soon, Iwasaki, Motoki, Hartman, Mikael, Takahashi, Atsushi, Ashikawa, Kyota, Matsuda, Koichi, Shin, Min-Ho, Park, Min Ho, Zheng, Ying, Xiang, Yong-Bing, Ji, Bu-Tian, Park, Sue K, Wu, Pei-Ei, Hsiung, Chia-Ni, Ito, Hidemi, Kasuga, Yoshio, Kang, Peter, Mariapun, Shivaani, Ahn, Sei Hyun, Kang, Han Sung, Chan, Kelvin Y K, Man, Ellen P S, Iwata, Hiroji, Tsugane, Shoichiro, Miao, Hui, Liao, Jiemin, Nakamura, Yusuke, Kubo, Michiaki, Delahanty, Ryan J, Zhang, Yanfeng, Li, Bingshan, Li, Chun, Gao, Yu-Tang, Shu, Xiao-Ou, Kang, Daehee, Zheng, Wei

“…Qiuyin Cai and colleagues report a genome-wide association analysis for breast cancer in 22,780 cases and 24,181 controls from 14 studies as part of the Asia…”
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A genome-wide association study for melatonin secretion by Liu, Pi-Hua, Chuang, Gwo-Tsann, Hsiung, Chia-Ni, Yang, Wei-Shun, Ku, Hsiao-Chia, Lin, Yi-Ching, Chen, Yi-Shun, Huang, Yu-Yao, Lin, Chia-Hung, Li, Wen-Yi, Lin, Jou-Wei, Hsu, Chih-Neng, Hwang, Juey-Jen, Liao, Karen Chia-Wen, Hsieh, Meng-Lun, Lee, Hsiao-Lin, Shen, Chen-Yang, Chang, Yi-Cheng

“…Melatonin exerts a wide range of effects among various tissues and organs. However, there is currently no study to investigate the genetic determinants of…”
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The Causal Relationship of Circulating Triglyceride and Glycated Hemoglobin: A Mendelian Randomization Study by Hsiung, Chia-Ni, Chang, Yi-Cheng, Lin, Chien-Wei, Chang, Chia-Wei, Chou, Wen-Cheng, Chu, Hou-Wei, Su, Ming-Wei, Wu, Pei-Ei, Shen, Chen-Yang

“…Abstract Context The association between circulating triglyceride (TG) and glycated hemoglobin A1c (HbA1c), a biomarker for type 2 diabetes, has been widely…”
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B-Myb Induces APOBEC3B Expression Leading to Somatic Mutation in Multiple Cancers by Chou, Wen-Cheng, Chen, Wei-Ting, Hsiung, Chia-Ni, Hu, Ling-Yueh, Yu, Jyh-Cherng, Hsu, Huan-Ming, Shen, Chen-Yang

“…The key signature of cancer genomes is the accumulation of DNA mutations, the most abundant of which is the cytosine-to-thymine (C-to-T) transition that…”
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Blood multiomics reveal insights into population clusters with low prevalence of diabetes, dyslipidemia and hypertension by Su, Ming-Wei, Chang, Chung-Ke, Lin, Chien-Wei, Ling, Shiu-Jie, Hsiung, Chia-Ni, Chu, Hou-Wei, Wu, Pei-Ei, Shen, Chen-Yang

“…Diabetes, dyslipidemia and hypertension are important metabolic diseases that impose a great burden on many populations worldwide. However, certain population…”
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The Effect of MicroRNA-124 Overexpression on Anti-Tumor Drug Sensitivity by Chen, Shiau-Mei, Chou, Wen-Cheng, Hu, Ling-Yueh, Hsiung, Chia-Ni, Chu, Hou-Wei, Huang, Yuan-Ling, Hsu, Huan-Ming, Yu, Jyh-Cherng, Shen, Chen-Yang

“…MicroRNAs play critical roles in regulating various physiological processes, including growth and development. Previous studies have shown that microRNA-124…”
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A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study by Kim, Hyung-cheol, Lee, Ji-Young, Sung, Hyuna, Choi, Ji-Yeob, Park, Sue K, Lee, Kyoung-Mu, Kim, Young Jin, Go, Min Jin, Li, Lian, Cho, Yoon Shin, Park, Miey, Kim, Dong-Joon, Oh, Ji Hee, Kim, Jun-Woo, Jeon, Jae-Pil, Jeon, Soon-Young, Min, Haesook, Kim, Hyo Mi, Park, Jaekyung, Yoo, Keun-Young, Noh, Dong-Young, Ahn, Sei-Hyun, Lee, Min Hyuk, Kim, Sung-Won, Lee, Jong Won, Park, Byeong-Woo, Park, Woong-Yang, Kim, Eun-Hye, Kim, Mi Kyung, Han, Wonshik, Lee, Sang-Ah, Matsuo, Keitaro, Shen, Chen-Yang, Wu, Pei-Ei, Hsiung, Chia-Ni, Lee, Jong-Young, Kim, Hyung-Lae, Han, Bok-Ghee, Kang, Daehee

“…Although approximately 25 common genetic susceptibility loci have been identified to be independently associated with breast cancer risk through genome-wide…”
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Genome-wide association study for circulating fibroblast growth factor 21 and 23 by Chuang, Gwo-Tsann, Liu, Pi-Hua, Chyan, Tsui-Wei, Huang, Chen-Hao, Huang, Yu-Yao, Lin, Chia-Hung, Lin, Jou-Wei, Hsu, Chih-Neng, Tsai, Ru-Yi, Hsieh, Meng-Lun, Lee, Hsiao-Lin, Yang, Wei-shun, Robinson-Cohen, Cassianne, Hsiung, Chia-Ni, Shen, Chen-Yang, Chang, Yi-Cheng

“…Fibroblast growth factors (FGFs) 21 and 23 are recently identified hormones regulating metabolism of glucose, lipid, phosphate and vitamin D. Here we conducted…”
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SUMOylation of XRCC1 activated by poly (ADP-ribosyl)ation regulates DNA repair by Hu, Ling-Yueh, Chang, Che-Chang, Huang, Yen-Sung, Chou, Wen-Cheng, Lin, Ying-Mei, Ho, Chun-Chen, Chen, Wei-Ting, Shih, Hsiu-Ming, Hsiung, Chia-Ni, Wu, Pei-Ei, Shen, Chen-Yang

“…Abstract XRCC1 is an essential scaffold protein for base excision repair (BER) and helps to maintain genomic stability. XRCC1 has been indicated as a substrate…”
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Modifications of lipid pathways restrict SARS-CoV-2 propagation in human induced pluripotent stem cell-derived 3D airway organoids by Tsai, Ping-Hsing, Sun, Jun-Ren, Chien, Yueh, Chan, Man Sheung, Khor, Winnie, Yang, Hsin-Chou, Huang, Chih-Heng, Hsiung, Chia-Ni, Hwa, Teh-Yang, Lin, Yi-Ying, Yeh, Chih-Ling, Wang, Mong-Lien, Yang, Yi-Ping, Chen, Yuh-Min, Tsai, Fu-Ting, Lee, Meng-Shiue, Cheng, Yun-Hsiang, Tsai, Shan-Ko, Liu, Ping-Cheng, Chou, Shih-Jie, Chiou, Shih-Hwa

“…Human iPSC-derived airway organoids (iPSC-AOs) exhibit cellular heterogenicity resembling the human native airway. Bioinformatics analysis revealed a robust…”
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Susceptibility to Colorectal Cancer Based on HSD17B4 rs721673 and rs721675 Polymorphisms and Alcohol Intake among Taiwan Biobank Participants: A Retrospective Case Control Study Using the Nationwide Claims Data by Lin, Tzu-Chiao, Chuang, Min-Hua, Hsiung, Chia-Ni, Chang, Pi-Kai, Sun, Chien-An, Yang, Tsan, Chou, Yu-Ching, Hu, Je-Ming, Hsu, Chih-Hsiung

“…Colorectal cancer (CRC) is a major public health issue, and there are limited studies on the association between 17β-hydroxysteroid dehydrogenase type 4…”
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Fanconi anemia genes in lung adenocarcinoma- a pathway-wide study on cancer susceptibility by Yang, Shi-Yi, Hsiung, Chia-Ni, Li, Yao-Jen, Chang, Gee-Chen, Tsai, Ying-Huang, Chen, Kuan-Yu, Huang, Ming-Shyan, Su, Wu-Chou, Chen, Yuh-Min, Hsiung, Chao A, Yang, Pan-Chyr, Chen, Chien-Jen, Wu, Pei-Ei, Yu, Jyh-Cherng, Shen, Chen-Yang, Hsu, Huan-Ming

“…Carcinogens in cigarette smoke can induce the formation of DNA-DNA cross-links, which are repaired by the Fanconi anemia (FA) pathway, and it is tempting to…”
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High Prevalence of the BIM Deletion Polymorphism in Young Female Breast Cancer in an East Asian Country by Lin, Ching-Hung, Shen, Chen-Yang, Lee, Jih-Hsiang, Huang, Chiun-Sheng, Yang, Chih-Hsin, Kuo, Wen-Hung, Chang, Dwan-Ying, Hsiung, Chia-Ni, Kuo, Kuan-Ting, Chen, Wei-Wu, Chen, I-Chun, Wu, Pei-Fang, Kuo, Sung-Hsin, Chen, Chien-Jen, Lu, Yen-Shen, Cheng, Ann-Lii

“…A rapid surge of female breast cancer has been observed in young women in several East Asian countries. The BIM deletion polymorphism, which confers cell…”
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Serum Urate and Risk of Chronic Kidney Disease: A Mendelian Randomization Study Using Taiwan Biobank by Tsao, Hsiao-Mei, Lai, Tai-Shuan, Chang, Yi-Cheng, Hsiung, Chia-Ni, Chou, Yu-Hsiang, Wu, Vin-Cent, Lin, Shuei-Liong, Chen, Yung-Ming

“…To evaluate the association between serum urate and risk of incident chronic kidney disease (CKD) and to assess whether serum urate plays a causal role in CKD…”
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Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway by Chou, Wen-Cheng, Hu, Ling-Yueh, Hsiung, Chia-Ni, Shen, Chen-Yang

“…The DNA damage response (DDR) is activated by various genotoxic stresses. Base lesions, which are structurally simple and predominantly fixed by base excision…”
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Genome-wide association analysis identifies three new breast cancer susceptibility loci by Fletcher, Olivia, Turnbull, Clare, Dicks, Ed, Dennis, Joe, Luccarini, Craig, Baynes, Caroline, Driver, Kristy, Orr, Nicholas, dos Santos Silva, Isabel, Uitterlinden, Andre G, Rivadeneira, Fernando, Hall, Per, Czene, Kamila, Aittomäki, Kristiina, Meindl, Alfons, Lichtner, Peter, Nickels, Stefan, Flesch-Janys, Dieter, Tsimiklis, Helen, Schmidt, Daniel, Bui, Minh, Apicella, Carmel, Park, Daniel J, Chanock, Stephen J, Verhoef, Senno, Hogervorst, Frans B L, Fasching, Peter A, Beckmann, Matthias W, Ekici, Arif B, Tomlinson, Ian, Kerin, Michael, Sohn, Christof, Burwinkel, Barbara, Guénel, Pascal, Truong, Thérèse, Menegaux, Florence, Nordestgaard, Børge G, Flyger, Henrik, Milne, Roger L, Alonso, M Rosario, Benítez, Javier, Anton-Culver, Hoda, Ziogas, Argyrios, Brenner, Hermann, Stegmaier, Christa, Brauch, Hiltrud, Brüning, Thomas, Eilber, Ursula, Bremer, Michael, Hillemanns, Peter, Antonenkova, Natalia N, Rogov, Yuri I, Karstens, Johann H, Bermisheva, Marina, Khusnutdinova, Elza, Lindblom, Annika, Margolin, Sara, Mannermaa, Arto, Hartikainen, Jaana M, Floris, Giuseppe, Fortuzzi, Stefano, Peterlongo, Paolo, Couch, Fergus J, Stevens, Kristen, Giles, Graham G, Baglietto, Laura, Severi, Gianluca, Alnæs, Grethe Grenaker, Kristensen, Vessela, Børrensen-Dale, Anne-Lise, John, Esther M, Miron, Alexander, Andrulis, Irene L, Devilee, Peter, Seynaeve, Caroline, Figueroa, Jonine D, Garcia-Closas, Montserrat, Brinton, Louise, Hooning, Maartje J, van den Ouweland, Ans M W, Reed, Malcolm W R, Shah, Mitul, Jakubowska, Ania, Lubinski, Jan, Durda, Katarzyna, Jones, Michael, Schoemaker, Minouk, Swerdlow, Anthony, Beesley, Jonathan, Chen, Xiaoqing, Lophatananon, Artitaya, Rattanamongkongul, Suthee, Noh, Dong-Young, Velentzis, Louiza, Tapper, Will J, Gerty, Susan M, Graham, Nikki J, Ponder, Bruce A J, Dunning, Alison M, Peto, Julian

“…Douglas Easton and colleagues report a genome-wide association analyses for breast cancer in ~70,000 cases and ~68,000 controls. They identify three new breast…”
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Detecting Genetic Ancestry and Adaptation in the Taiwanese Han People by Lo, Yun-Hua, Cheng, Hsueh-Chien, Hsiung, Chia-Ni, Yang, Show-Ling, Wang, Han-Yu, Peng, Chia-Wei, Chen, Chun-Yu, Lin, Kung-Ping, Kang, Mei-Ling, Chen, Chien-Hsiun, Chu, Hou-Wei, Lin, Chiao-Feng, Lee, Mei-Hsuan, Liu, Quintin, Satta, Yoko, Lin, Cheng-Jui, Lin, Marie, Chaw, Shu-Miaw, Loo, Jun-Hun, Shen, Chen-Yang, Ko, Wen-Ya

“…Abstract The Taiwanese people are composed of diverse indigenous populations and the Taiwanese Han. About 95% of the Taiwanese identify themselves as Taiwanese…”
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A novel estrogen receptor-microRNA 190a-PAR-1-pathway regulates breast cancer progression, a finding initially suggested by genome-wide analysis of loci associated with lymph-node metastasis by Chu, Hou-Wei, Cheng, Chun-Wen, Chou, Wen-Cheng, Hu, Ling-Yueh, Wang, Hsiao-Wei, Hsiung, Chia-Ni, Hsu, Huan-Ming, Wu, Pei-Ei, Hou, Ming-Feng, Shen, Chen-Yang, Yu, Jyh-Cherng

“…To identify microRNAs that are important in regulating breast cancer progression, the present study used data for the 199 961 single-nucleotide polymorphisms…”
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