Search Results - "Hsin‐Ling Yang"

Anti-EMT properties of CoQ0 attributed to PI3K/AKT/NFKB/MMP-9 signaling pathway through ROS-mediated apoptosis by Yang, Hsin-Ling, Thiyagarajan, Varadharajan, Shen, Pei-Chun, Mathew, Dony Chacko, Lin, Kai-Yuan, Liao, Jiunn-Wang, Hseu, You-Cheng

“…Breast cancer is the most prevalent cancer among women. In triple-negative breast cancer (TNBC) cells, a novel quinone derivative, coenzyme Q (CoQ ), promotes…”
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Improved Wound Healing by Naringin Associated with MMP and the VEGF Pathway by Yen, Jia-Hau, Chio, Wan-Ting, Chuang, Chia-Ju, Yang, Hsin-Ling, Huang, Sheng-Teng

“…This study aims to investigate the wound-healing effectiveness of the phenolic compound, naringin, both in vitro and in vivo. Male mice were shaved on their…”
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Anticancer activities of chalcone flavokawain B from Alpinia pricei Hayata in human lung adenocarcinoma (A549) cells via induction of reactive oxygen species‐mediated apoptotic and autophagic cell death by Hseu, You‐Cheng, Huang, Yu‐Chi, Thiyagarajan, Varadharajan, Mathew, Dony Chacko, Lin, Kai‐Yuan, Chen, Ssu‐Ching, Liu, Jer‐Yuh, Hsu, Li‐Sung, Li, Mei‐Ling, Yang, Hsin‐Ling

“…Chalcones found in fruits and vegetables have promising cancer chemopreventive properties. This study attempts to identify the anticancer efficacies of…”
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Dermato-protective properties of ergothioneine through induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated Human keratinocytes by Hseu, You-Cheng, Lo, Heng-Wei, Korivi, Mallikarjuna, Tsai, Yu-Cheng, Tang, Meng-Ju, Yang, Hsin-Ling

“…UVA irradiation-induced skin damage and redox imbalance have been shown to be ameliorated by ergothioneine (EGT), a naturally occurring sulfur-containing amino…”
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Antrodia camphorata and coenzyme Q0, a novel quinone derivative of Antrodia camphorata, impede HIF‐1α and epithelial‐mesenchymal transition/metastasis in human glioblastoma cells by Yang, Hsin‐Ling, Chang, Yao‐Hsien, Pandey, Sudhir, Bhat, Asif Ali, Vadivalagan, Chithravel, Lin, Kai‐Yuan, Hseu, You‐Cheng

“…Antrodia camphorata (AC) and Coenzyme Q0 (CoQ0), a novel quinone derivative of AC, exhibits antitumor activities. The present study evaluated EMT/metastasis…”
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Zerumbone protects human skin keratinocytes against UVA-irradiated damages through Nrf2 induction by Yang, Hsin-Ling, Lee, Chin-Ling, Korivi, Mallikarjuna, Liao, Jiunn-Wang, Rajendran, Peramaiyan, Wu, Jia-Jiuan, Hseu, You-Cheng

“…[Display omitted] Ultraviolet A (UVA) irradiation is toxic to skin as it penetrates deep into the dermis and damages cellular components through excessive…”
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CoQ0-induced mitochondrial PTP opening triggers apoptosis via ROS-mediated VDAC1 upregulation in HL-60 leukemia cells and suppresses tumor growth in athymic nude mice/xenografted nude mice by Hseu, You-Cheng, Thiyagarajan, Varadharajan, Ou, Ting-Tsz, Yang, Hsin-Ling

“…Coenzyme Q (CoQ) analogs with variable numbers of isoprenoid units have been demonstrated as anticancer and antioxidant/pro-oxidant molecules. This study…”
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The Antiaging Activity of Ergothioneine in UVA-Irradiated Human Dermal Fibroblasts via the Inhibition of the AP-1 Pathway and the Activation of Nrf2-Mediated Antioxidant Genes by Yang, Yi-Chen, Chen, Xuan-Zao, Gowrisankar, Yugandhar Vudhya, Hseu, You Cheng, Yang, Hsin-Ling

“…UVA irradiation induced ROS-mediated photo damage to the human skin leading to coarseness, wrinkling, pigmentation, and cutaneous malignancies. We investigated…”
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Antitumor properties of Coenzyme Q0 against human ovarian carcinoma cells via induction of ROS-mediated apoptosis and cytoprotective autophagy by Hseu, You-Cheng, Tsai, Tai-Jung, Korivi, Mallikarjuna, Liu, Jer-Yuh, Chen, Hui-Jye, Lin, Chung-Ming, Shen, Yi-Chun, Yang, Hsin-Ling

“…Coenzyme Q 0 (CoQ 0 , 2,3-dimethoxy-5-methyl-1,4-benzoquinone) has been reported to exert anticancer properties against human breast/lung cancer cells. This…”
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Trans-cinnamic acid attenuates UVA-induced photoaging through inhibition of AP-1 activation and induction of Nrf2-mediated antioxidant genes in human skin fibroblasts by Hseu, You-Cheng, Korivi, Mallikarjuna, Lin, Fang-Ying, Li, Mei-Ling, Lin, Ruei-Wan, Wu, Jia-Jiuan, Yang, Hsin-Ling

“…[Display omitted] •t-CA reverses UVA-induced ROS-mediated MMP-1/-3 induction and procollagen reduction.•t-CA attenuates AP-1 nuclear localization against UVA…”
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Ellagic acid protects human keratinocyte (HaCaT) cells against UVA-induced oxidative stress and apoptosis through the upregulation of the HO-1 and Nrf-2 antioxidant genes by Hseu, You-Cheng, Chou, Chih-Wei, Senthil Kumar, K.J., Fu, Ke-Ting, Wang, Hui-Min, Hsu, Li-Sung, Kuo, Yueh-Hsiung, Wu, Chi-Rei, Chen, Ssu-Ching, Yang, Hsin-Ling

“…► Ellagic acid treatment suppressed UVA-induced ROS generation and MDA formation. ► Ellagic acid treatment inhibited UVA-induced apoptosis in HaCaT cells. ►…”
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Induction of autophagic cell death in human ovarian carcinoma cells by Antrodia salmonea through increased reactive oxygen species generation by Yang, Hsin‐Ling, Lin, Ruei‐Wan, Karuppaiya, Palaniyandi, Mathew, Dony Chacko, Way, Tzong‐Der, Lin, Hui‐Chang, Lee, Chuan‐Chen, Hseu, You‐Cheng

“…We reported in our previously executed studies that the fermented culture broth of Antrodia salmonea (AS), a mushroom used in Taiwanese folk medicine induced…”
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The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways by Hseu, You-Cheng, Vudhya Gowrisankar, Yugandhar, Wang, Li-Wei, Zhang, Yan-Zhen, Chen, Xuan-Zao, Huang, Pei-Jane, Yen, Hung-Rong, Yang, Hsin-Ling

“…Pterostilbene (Pt) is a natural polyphenol found in blueberries and several grape varieties. Pt's pharmacological importance was well documented. Nevertheless,…”
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Chalcone flavokawain A attenuates TGF‐β1‐induced fibrotic pathology via inhibition of ROS/Smad3 signaling pathways and induction of Nrf2/ARE‐mediated antioxidant genes in vascular smooth muscle cells by Hseu, You‐Cheng, Yang, Ting‐Yu, Li, Mei‐Ling, Rajendran, Peramaiyan, Mathew, Dony Chacko, Tsai, Chia‐Hsuan, Lin, Ruei‐Wan, Lee, Chuan‐Chen, Yang, Hsin‐Ling

“…TGF‐β1 plays a crucial role in the pathogenesis of vascular fibrotic diseases. Chalcones are reportedly cancer chemo‐preventive food components that are rich…”
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Tranexamic acid improves psoriasis-like skin inflammation: Evidence from in vivo and in vitro studies by Hseu, Jhih-Hsuan, Chan, Chon-I., Vadivalagan, Chithravel, Chen, Siang-Jyun, Yen, Hung-Rong, Hseu, You-Cheng, Yang, Hsin-Ling, Wu, Po-Yuan

“…The chronic disease psoriasis is associated with severe inflammation and abnormal keratinocyte propagation in the skin. Tranexamic acid (TXA), a plasmin…”
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The in vitro and in vivo depigmentation activity of coenzyme Q0, a major quinone derivative from Antrodia camphorata, through autophagy induction in human melanocytes and keratinocytes by Hseu, You-Cheng, Yeh, Jou-Tsen, Vadivalagan, Chithravel, Chen, Siang-Jyun, Gowrisankar, Yugandhar Vudhya, Pandey, Sudhir, Hsu, Yuan-Tai, Yen, Hung-Rong, Huang, Hui-Chi, Hseu, Jhih-Hsuan, Yang, Hsin-Ling

“…Coenzyme Q.sub.0 (CoQ.sub.0), a novel quinone derivative of Antrodia camphorata, has been utilized as a therapeutic agent (including antioxidant,…”
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Antrodia camphorata inhibits epithelial‐to‐mesenchymal transition by targeting multiple pathways in triple‐negative breast cancers by Hseu, You‐Cheng, Chang, Geng‐Ruei, Pan, Jian‐You, Rajendran, Peramaiyan, Mathew, Dony Chacko, Li, Mei‐Ling, Liao, Jiunn‐Wang, Chen, William Tzu‐Liang, Yang, Hsin‐Ling

“…Antrodia camphorata (AC) exhibits potential for engendering cell‐cycle arrest as well as prompting apoptosis and metastasis inhibition in triple‐negative…”
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Antrodia salmonea‐induced oxidative stress abrogates HER‐2 signaling cascade and enhanced apoptosis in ovarian carcinoma cells by Yang, Hsin‐Ling, Lin, Ruei‐Wan, Rajendran, Peramaiyan, Mathew, Dony Chacko, Thigarajan, Varadharajan, Lee, Chuan‐Chen, Hsu, Chih‐Jung, Hseu, You‐Cheng

“…Antrodia salmonea is well known in Taiwan as a traditional Chinese medicinal fungus and has demonstrated antioxidant, anti‐inflammatory, and anticancer…”
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The Skin-Whitening Effects of Ectoine via the Suppression of α-MSH-Stimulated Melanogenesis and the Activation of Antioxidant Nrf2 Pathways in UVA-Irradiated Keratinocytes by Hseu, You-Cheng, Chen, Xuan-Zao, Vudhya Gowrisankar, Yugandhar, Yen, Hung-Rong, Chuang, Jing-Yuan, Yang, Hsin-Ling

“…Ultraviolet A (UVA)-irradiation induced reactive oxygen species (ROS) production mediates excessive melanogenesis in skin cells leading to pigmentation. We…”
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Suppression of LPS-Induced Inflammation by Chalcone Flavokawain A through Activation of Nrf2/ARE-Mediated Antioxidant Genes and Inhibition of ROS/NFκB Signaling Pathways in Primary Splenocytes by Hseu, You Cheng, Liao, Jiunn-Wang, Liao, Chun-Huei, Gowrisankar, Yugandhar Vudhya, Yang, Ting-Yu, Yang, Hsin-Ling, Huang, Pei-Jane

“…Oxidative stress is an important contributing factor for inflammation. Piper methysticum, also known as Kava-kava, is a shrub whose root extract has been…”
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