Search Results - "Hsieh, Adam H"

Effect of Dynamic Culture and Periodic Compression on Human Mesenchymal Stem Cell Proliferation and Chondrogenesis by Guo, Ting, Yu, Li, Lim, Casey G., Goodley, Addison S., Xiao, Xuan, Placone, Jesse K., Ferlin, Kimberly M., Nguyen, Bao-Ngoc B., Hsieh, Adam H., Fisher, John P.

“…We have recently developed a bioreactor that can apply both shear and compressive forces to engineered tissues in dynamic culture. In our system, alginate…”
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Degenerative Anular Changes Induced by Puncture Are Associated With Insufficiency of Disc Biomechanical Function by HSIEH, Adam H, HWANG, David, RYAN, David A, FREEMAN, Anike K, KIM, Hyunchul

“…In vivo experiments to examine physiologic consequences and in vitro tests to determine immediate biomechanical effects of anular injury by needle puncture. To…”
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Pressure and Distortion Regulate Human Mesenchymal Stem Cell Gene Expression by Haudenschild, Anne K, Hsieh, Adam H, Kapila, Sunil, Lotz, Jeffrey C

“…While the concept that physical forces such as tension and compression are involved in mature tissue modeling is widely accepted, the role of these specific…”
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Biomechanical comparison of the pullout strengths of C1 lateral mass screws and C1 posterior arch screws by Zarro, Christopher M., MD, Ludwig, Steven C., MD, Hsieh, Adam H., PhD, Seal, Charles N., MD, Gelb, Daniel E., MD

“…Abstract Background context Conditions of the atlantoaxial complex requiring internal stabilization can result from trauma, malignancy, inflammatory diseases,…”
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Enhancing Biocompatibility of D‑Oligopeptide Hydrogels by Negative Charges by Hyland, Laura L, Twomey, Julianne D, Vogel, Savannah, Hsieh, Adam H, Yu, Y. Bruce

“…Oligopeptide hydrogels are emerging as useful matrices for cell culture with commercial products on the market, but L-oligopeptides are labile to proteases. An…”
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Environmental regulation of notochordal gene expression in nucleus pulposus cells by Rastogi, Anshu, Thakore, Pratiksha, Leung, Aileen, Benavides, Magda, Machado, Monica, Morschauser, Michael A., Hsieh, Adam H.

“…Cells of the nucleus pulposus (NP) in the intervertebral disc are derived directly from the embryonic notochord. In humans, a shift in NP cell population…”
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Effects of proinflammatory cytokines on axonal outgrowth from adult rat lumbar dorsal root ganglia using a novel three-dimensional culture system by Kim, Hyunchul, MS, W. Caspar, Tyler, BS, Shah, Sameer B., PhD, Hsieh, Adam H., PhD

“…Abstract Background context Degeneration of the intervertebral disc is often associated with low back pain and increased infiltration of nerve fibers…”
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A biomechanical comparison of multidirectional nail and locking plate fixation in unstable olecranon fractures by Argintar, Evan, MD, Martin, Benjamin D., MD, Singer, Andrea, MD, Hsieh, Adam H., PhD, Edwards, Scott, MD

“…Background The main theoretic advantage of proximal olecranon fracture intramedullary fixation is decreased soft-tissue irritation and, potentially, less…”
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Downregulation of vimentin intermediate filaments affect human mesenchymal stem cell adhesion and formation of cellular projections by Sharma, Poonam, Burch, Shalise, Peesay, Tejasvi, M. Hamilla, Susan, H. Hsieh, Adam, Luna Lopez, Carlos

“…Mesenchymal stem cells hold great promise as a therapeutic cell source for a variety of diseases such as osteoarthritis and degenerative disc disease. Their…”
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Prolonged spinal loading induces matrix metalloproteinase-2 activation in intervertebral discs by Hsieh, Adam H, Lotz, Jeffrey C

“…An established in vivo mouse model of compression-induced disc degeneration was used to investigate the effects of load on matrix catabolism. To determine…”
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Effects of Angular Frequency During Clinorotation on Mesenchymal Stem Cell Morphology and Migration by Luna, Carlos, Yew, Alvin G, Hsieh, Adam H

“…Background/Objectives: Ground-based microgravity simulation can reproduce the apparent effects of weightlessness in spaceflight using clinostats that…”
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The vacuolated morphology of chordoma cells is dependent on cytokeratin intermediate filaments by Resutek, Lauren, Hsieh, Adam H.

“…Notochordal cells (NCs), characterized by their vacuolated morphology and coexpression of cytokeratin and vimentin intermediate filaments (IFs), form the…”
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Bar Diameter Is an Important Component of Knee-Spanning External Fixator Stiffness and Cost by Kim, Hyunchul, Russell, Joseph P, Hsieh, Adam H, O'Toole, Robert V

“…The authors’ objective was to determine the effects of bar diameter on the stiffness and cost of a knee-spanning external fixator. The authors studied 2…”
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Deformability of Human Mesenchymal Stem Cells Is Dependent on Vimentin Intermediate Filaments by Sharma, Poonam, Bolten, Zachary T., Wagner, Diane R., Hsieh, Adam H.

“…Mesenchymal stem cells (MSCs) are being studied extensively due to their potential as a therapeutic cell source for many load-bearing tissues. Compression of…”
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Cellular mechanobiology of the intervertebral disc: New directions and approaches by Hsieh, Adam H, Twomey, Julianne D

“…Abstract The more we learn about the intervertebral disc (IVD), the more we come to appreciate the intricacies involved in transmission of forces through the…”
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Axial strain enhances osteotomy repair with a concomitant increase in connexin43 expression by Gupta, Rishi R, Kim, Hyunchul, Chan, Yu-Kwan, Hebert, Carla, Gitajn, Leah, Yoo, David J, O'Toole, Robert V, Hsieh, Adam H, Stains, Joseph P

“…The mechanical environment is known to influence fracture healing. We speculated that connexin43 (Cx43) gap junctions, which impact skeletal homeostasis,…”
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MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc by Rastogi, Anshu, Kim, Hyunchul, Twomey, Julianne D, Hsieh, Adam H

“…Degeneration of the intervertebral disc (IVD) is characterized by marked degradation and restructuring of the annulus fibrosus (AF). Although several matrix…”
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The Effect of Distal Radius Locking Plates on Articular Contact Pressures by Walker, Matthew H., MD, Kim, Hyunchul, MS, Hsieh, Adam H., PhD, O'Toole, Robert V., MD, Eglseder, W. Andrew, MD

“…Purpose Fractures of the distal radius are among the most common injuries treated in hand surgery practice, and distal radius locking plates have become an…”
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Ultrasonic Structural Health Monitoring to Assess the Integrity of Spinal Growing Rods In Vitro by Oetgen, Matthew E, Goodley, Addison, Yoo, Byungseok, Pines, Darryll J, Hsieh, Adam H

“…Rod fracture is a common complication of growing rods and can result in loss of correction, patient discomfort, and unplanned revision surgery. The ability to…”
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A Biomechanical Comparison of Allograft Tendons for Ligament Reconstruction by Palmer, Jeremiah E., Russell, Joseph P., Grieshober, Jason, Iacangelo, Abigail, Ellison, Benjamin A., Lease, T. Dylan, Kim, Hyunchul, Henn, R. Frank, Hsieh, Adam H.

“…Background: Allograft tendons are frequently used for ligament reconstruction about the knee, but they entail availability and cost challenges. The…”
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